AU2007240491A1 - Tetramerizing polypeptides and methods of use - Google Patents

Tetramerizing polypeptides and methods of use Download PDF

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Publication number
AU2007240491A1
AU2007240491A1 AU2007240491A AU2007240491A AU2007240491A1 AU 2007240491 A1 AU2007240491 A1 AU 2007240491A1 AU 2007240491 A AU2007240491 A AU 2007240491A AU 2007240491 A AU2007240491 A AU 2007240491A AU 2007240491 A1 AU2007240491 A1 AU 2007240491A1
Authority
AU
Australia
Prior art keywords
protein
vasp
cells
heterologous
fusion protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007240491A
Other languages
English (en)
Inventor
Cameron S. Brandt
James W. West
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU2007240491A1 publication Critical patent/AU2007240491A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70532B7 molecules, e.g. CD80, CD86
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU2007240491A 2006-04-13 2007-04-13 Tetramerizing polypeptides and methods of use Abandoned AU2007240491A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79162606P 2006-04-13 2006-04-13
US60/791,626 2006-04-13
PCT/US2007/066607 WO2007124283A2 (en) 2006-04-13 2007-04-13 Tetramerizing polypeptides and methods of use

Publications (1)

Publication Number Publication Date
AU2007240491A1 true AU2007240491A1 (en) 2007-11-01

Family

ID=38617337

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007240491A Abandoned AU2007240491A1 (en) 2006-04-13 2007-04-13 Tetramerizing polypeptides and methods of use

Country Status (7)

Country Link
US (1) US20070254339A1 (https=)
EP (1) EP2004682A2 (https=)
JP (1) JP2009538120A (https=)
AU (1) AU2007240491A1 (https=)
CA (1) CA2648915A1 (https=)
IL (1) IL194161A0 (https=)
WO (1) WO2007124283A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040121370A1 (en) 2002-09-11 2004-06-24 Genentech, Inc. Novel composition and methods for the treatment of immune related diseases
EP1997887B1 (en) 2006-03-03 2013-09-04 Ono Pharmaceutical Co., Ltd. Multimer of extracellular domain of cell surface functional molecule
US20070243584A1 (en) * 2006-04-13 2007-10-18 West James W Tetramerizing polypeptides and methods of use
KR101662622B1 (ko) 2007-10-04 2016-10-05 지모제넥틱스, 인코포레이티드 B7 패밀리 구성원 zB7H6 및 관련된 조성물 및 방법
EP3208612B1 (en) 2008-04-09 2019-09-18 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US8822642B2 (en) 2010-06-09 2014-09-02 Zymogenetics, Inc. Dimeric fusion proteins and related compositions and methods
CA2916681A1 (en) 2013-07-16 2015-01-22 Genentech, Inc. Methods of treating cancer using pd-1 axis binding antagonists and tigit inhibitors
US10227408B2 (en) 2015-02-19 2019-03-12 Compugen Ltd. Anti-PVRIG antibodies and methods of use
EP3978929A1 (en) 2015-02-19 2022-04-06 Compugen Ltd. Pvrig polypeptides and methods of treatment
CA2994858C (en) 2015-09-25 2024-01-23 Genentech, Inc. Anti-tigit antibodies and methods of use
CN106565836B (zh) * 2015-10-10 2020-08-18 中国科学院广州生物医药与健康研究院 高亲和力的可溶性pdl-1分子
WO2017152088A1 (en) 2016-03-04 2017-09-08 JN Biosciences, LLC Antibodies to tigit
CN110088132B (zh) 2016-08-17 2020-10-27 康姆普根有限公司 抗tigit抗体,抗pvrig抗体及其组合
US11142558B2 (en) 2017-04-06 2021-10-12 Universität Stuttgart Tumor necrosis factor receptor (TNFR) binding protein complex with improved binding and bioactivity
CN110799213A (zh) 2017-06-01 2020-02-14 康姆普根有限公司 三联组合抗体疗法
JP2021534196A (ja) 2018-08-23 2021-12-09 シージェン インコーポレイテッド 抗tigit抗体
EP4582442A3 (en) 2019-06-24 2025-10-29 Universität Stuttgart Tnfr2 agonists with improved stability
BR112022024221A2 (pt) 2020-06-02 2022-12-20 Arcus Biosciences Inc Anticorpos para tigit

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803192B1 (en) * 1999-11-30 2004-10-12 Mayo Foundation For Medical Education And Research B7-H1, a novel immunoregulatory molecule
US20020107363A1 (en) * 2000-09-20 2002-08-08 Amgen, Inc. B7-Like molecules and uses thereof
PL368972A1 (en) * 2001-08-29 2005-04-04 Genentech, Inc. Bv8 nucleic acids and polypeptides with mitogenic activity
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
US20040121370A1 (en) * 2002-09-11 2004-06-24 Genentech, Inc. Novel composition and methods for the treatment of immune related diseases
EP3214095B1 (en) * 2005-05-12 2019-12-11 ZymoGenetics, Inc. Compositions and methods for modulating immune responses

Also Published As

Publication number Publication date
WO2007124283A3 (en) 2008-01-17
CA2648915A1 (en) 2007-11-01
JP2009538120A (ja) 2009-11-05
US20070254339A1 (en) 2007-11-01
IL194161A0 (en) 2011-08-01
EP2004682A2 (en) 2008-12-24
WO2007124283A2 (en) 2007-11-01

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period