CA2648327A1 - Tissue engineering with human embryonic stem cells - Google Patents
Tissue engineering with human embryonic stem cells Download PDFInfo
- Publication number
- CA2648327A1 CA2648327A1 CA002648327A CA2648327A CA2648327A1 CA 2648327 A1 CA2648327 A1 CA 2648327A1 CA 002648327 A CA002648327 A CA 002648327A CA 2648327 A CA2648327 A CA 2648327A CA 2648327 A1 CA2648327 A1 CA 2648327A1
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- constructs
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- embryoid bodies
- embryonic stem
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
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Landscapes
- Health & Medical Sciences (AREA)
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- Developmental Biology & Embryology (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
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| US78985106P | 2006-04-05 | 2006-04-05 | |
| US78985506P | 2006-04-05 | 2006-04-05 | |
| US78985306P | 2006-04-05 | 2006-04-05 | |
| US60/789,853 | 2006-04-05 | ||
| US60/789,851 | 2006-04-05 | ||
| US60/789,855 | 2006-04-05 | ||
| PCT/US2007/066092 WO2007115337A2 (en) | 2006-04-05 | 2007-04-05 | Chondrocyte differentiation from human embryonic stem cells and their use in tissue engineering |
Publications (1)
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| CA2648327A1 true CA2648327A1 (en) | 2007-10-11 |
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| CA002648332A Abandoned CA2648332A1 (en) | 2006-04-05 | 2007-04-05 | A shape-based approach for scaffoldless tissue engineering |
| CA002648648A Abandoned CA2648648A1 (en) | 2006-04-05 | 2007-04-05 | Dermis-derived cells for tissue engineering applications |
| CA002648327A Abandoned CA2648327A1 (en) | 2006-04-05 | 2007-04-05 | Tissue engineering with human embryonic stem cells |
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| CA002648332A Abandoned CA2648332A1 (en) | 2006-04-05 | 2007-04-05 | A shape-based approach for scaffoldless tissue engineering |
| CA002648648A Abandoned CA2648648A1 (en) | 2006-04-05 | 2007-04-05 | Dermis-derived cells for tissue engineering applications |
Country Status (4)
| Country | Link |
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| EP (3) | EP2007312A4 (de) |
| AU (3) | AU2007234366A1 (de) |
| CA (3) | CA2648332A1 (de) |
| WO (3) | WO2007115337A2 (de) |
Families Citing this family (22)
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| WO2005058207A1 (en) | 2003-12-11 | 2005-06-30 | Isto Technologies, Inc. | Particulate cartilage system |
| US8241905B2 (en) | 2004-02-24 | 2012-08-14 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
| WO2010022074A1 (en) * | 2008-08-18 | 2010-02-25 | William Marsh Rice University | A decellularization method for scaffoldless tissue engineered articular cartilage or native cartilage tissue |
| WO2009111390A1 (en) * | 2008-03-03 | 2009-09-11 | William Marsh Rice University | Methods of fabricating enhanced tissue-engineered cartilage |
| US20110212894A1 (en) * | 2004-07-09 | 2011-09-01 | Athanasiou Kyriacos A | Decellularization method for scaffoldless tissue engineered articular cartilage or native cartilage tissue |
| US8480757B2 (en) | 2005-08-26 | 2013-07-09 | Zimmer, Inc. | Implants and methods for repair, replacement and treatment of disease |
| US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
| CA2684040C (en) | 2007-04-12 | 2016-12-06 | Isto Technologies, Inc. | Method of forming an implant using a mold that mimics the shape of the tissue defect site and implant formed therefrom |
| WO2009154466A1 (en) * | 2008-06-20 | 2009-12-23 | Universiteit Twente | Self-assembling tissue modules |
| US8143055B2 (en) | 2008-06-24 | 2012-03-27 | The Curators Of The University Of Missouri | Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same |
| CN102844036B (zh) * | 2009-07-16 | 2016-01-20 | 生物时代股份有限公司 | 用于体外和体内软骨发生的方法和组合物 |
| DK2629975T3 (da) | 2010-10-21 | 2022-05-09 | Organovo Inc | Anordninger til fremstilling af væv |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| US9499779B2 (en) | 2012-04-20 | 2016-11-22 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking |
| US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
| US9442105B2 (en) | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
| AU2014296246B2 (en) | 2013-07-31 | 2021-01-21 | Organovo, Inc. | Automated devices, systems, and methods for the fabrication of tissue |
| CA2944723C (en) | 2014-04-04 | 2023-03-14 | Organovo, Inc. | Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model |
| US9670443B2 (en) | 2014-06-25 | 2017-06-06 | University Of Leeds | Tissue engineered constructs |
| JP2017529877A (ja) | 2014-10-06 | 2017-10-12 | オルガノボ インコーポレイテッド | 人工の腎臓組織、そのアレイ、およびその作製方法 |
| US20160122723A1 (en) | 2014-11-05 | 2016-05-05 | Organovo, Inc. | Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same |
| AU2016352873B2 (en) | 2015-11-09 | 2023-01-05 | Organovo, Inc. | Improved methods for tissue fabrication |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997017038A1 (en) * | 1995-11-09 | 1997-05-15 | University Of Massachusetts | Tissue re-surfacing with hydrogel-cell compositions |
| AU3391300A (en) * | 1999-03-02 | 2000-09-21 | University Of Massachusetts | Embryonic or stem-like cell lines produced by cross species nuclear transplantation |
| JP2004504834A (ja) * | 2000-08-01 | 2004-02-19 | イスム リサーチ ディベロップメント カンパニー | 胚性細胞の定方向分化 |
| AU2002258477A1 (en) * | 2001-03-08 | 2002-09-24 | Advanced Cell Technology, Inc. | Use of rna interference for the creation of lineage specific es and other undifferentiated cells and production of differentiated cells in vitro by co-culture |
| WO2003050250A2 (en) * | 2001-12-07 | 2003-06-19 | Geron Corporation | Chondrocyte precursors derived from human embryonic stem cells |
| US20020106625A1 (en) * | 2002-02-07 | 2002-08-08 | Hung Clark T. | Bioreactor for generating functional cartilaginous tissue |
| US20030215426A1 (en) * | 2002-04-02 | 2003-11-20 | William Marsh Rice University | Redifferentiated cells for repairing cartilage defects |
| US20040082063A1 (en) * | 2002-10-18 | 2004-04-29 | Reliance Life Sciences Pvt. Ltd. | Tissue-like organization of cells and macroscopic tissue-like constructs, generated by macromass culture of cells, and the method of macromass culture |
| EP1819290B1 (de) * | 2004-07-09 | 2011-03-02 | William Marsh Rice University | Gerüstlose konstrukte für die erzeugung von gelenkknorpel aus gewebe |
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- 2007-04-05 CA CA002648332A patent/CA2648332A1/en not_active Abandoned
- 2007-04-05 AU AU2007234366A patent/AU2007234366A1/en not_active Abandoned
- 2007-04-05 EP EP07760211A patent/EP2007881A4/de not_active Withdrawn
- 2007-04-05 CA CA002648648A patent/CA2648648A1/en not_active Abandoned
- 2007-04-05 WO PCT/US2007/066092 patent/WO2007115337A2/en active Application Filing
- 2007-04-05 CA CA002648327A patent/CA2648327A1/en not_active Abandoned
- 2007-04-05 AU AU2007234365A patent/AU2007234365A1/en not_active Abandoned
- 2007-04-05 AU AU2007254048A patent/AU2007254048A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2007881A2 (de) | 2008-12-31 |
| WO2007115336A2 (en) | 2007-10-11 |
| AU2007254048A1 (en) | 2007-11-29 |
| EP2007312A2 (de) | 2008-12-31 |
| EP2007875A2 (de) | 2008-12-31 |
| EP2007312A4 (de) | 2012-08-22 |
| WO2007115337A3 (en) | 2008-07-03 |
| EP2007881A4 (de) | 2009-07-08 |
| CA2648648A1 (en) | 2007-11-29 |
| AU2007234365A1 (en) | 2007-10-11 |
| WO2007136936A3 (en) | 2008-10-23 |
| EP2007875A4 (de) | 2009-12-16 |
| WO2007115337A8 (en) | 2007-12-13 |
| CA2648332A1 (en) | 2007-10-11 |
| WO2007115336A3 (en) | 2008-05-22 |
| WO2007115337A2 (en) | 2007-10-11 |
| AU2007234366A1 (en) | 2007-10-11 |
| WO2007136936A2 (en) | 2007-11-29 |
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