CA2647843A1 - Detection of proteins from circulating neoplastic cells - Google Patents

Detection of proteins from circulating neoplastic cells Download PDF

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Publication number
CA2647843A1
CA2647843A1 CA002647843A CA2647843A CA2647843A1 CA 2647843 A1 CA2647843 A1 CA 2647843A1 CA 002647843 A CA002647843 A CA 002647843A CA 2647843 A CA2647843 A CA 2647843A CA 2647843 A1 CA2647843 A1 CA 2647843A1
Authority
CA
Canada
Prior art keywords
protein
cancer cells
immunoassay
detecting
egfr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002647843A
Other languages
English (en)
French (fr)
Inventor
Robert M. Lorence
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellstat Biologics Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2647843A1 publication Critical patent/CA2647843A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002647843A 2006-04-18 2007-04-18 Detection of proteins from circulating neoplastic cells Abandoned CA2647843A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74501606P 2006-04-18 2006-04-18
US60/745,016 2006-04-18
PCT/US2007/066857 WO2007121465A2 (en) 2006-04-18 2007-04-18 Detection of proteins from circulating neoplastic cells

Publications (1)

Publication Number Publication Date
CA2647843A1 true CA2647843A1 (en) 2007-10-25

Family

ID=38610457

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002647843A Abandoned CA2647843A1 (en) 2006-04-18 2007-04-18 Detection of proteins from circulating neoplastic cells

Country Status (6)

Country Link
US (1) US8012480B2 (enExample)
EP (1) EP2008102A4 (enExample)
JP (1) JP5025724B2 (enExample)
CA (1) CA2647843A1 (enExample)
MX (1) MX2008013332A (enExample)
WO (1) WO2007121465A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4798801B2 (ja) * 2004-10-06 2011-10-19 ウェルスタット バイオロジクス コーポレイション 循環する癌細胞におけるHer−2/neuタンパク質のレベルの上昇の検出および処置
JP2010525326A (ja) * 2007-04-19 2010-07-22 ウェルスタット バイオロジックス コーポレイション 分離されていない循環癌細胞由来のHer−2/neuタンパク質の上昇したレベルの検出および治療
US11072655B2 (en) 2008-01-15 2021-07-27 The Board Of Trustees Of The Leland Stanford Junior University Markers of acute myeloid leukemia stem cells
PT3056515T (pt) 2008-01-15 2019-07-19 Univ Leland Stanford Junior Métodos para manipulação da fagocitose mediada por cd47
PT4160212T (pt) 2008-01-15 2024-06-25 Univ Leland Stanford Junior Marcadores de células estaminais de leucemia mielóide aguda
US20120093733A1 (en) * 2010-05-24 2012-04-19 Marek Malecki Multidomain biotags for cancer detection, diagnosis and therapy and methods of their use
EP2628008B1 (en) * 2010-10-14 2017-05-31 Janssen Diagnostics, LLC Methods and kits for the detection of circulating tumor cells in pancreatic patients using polyspecific capture and cocktail detection reagents
CN102680456B (zh) * 2011-03-16 2015-07-08 北京联众泰克科技有限公司 一种电化学发光免疫测定方法
WO2013003624A2 (en) 2011-06-29 2013-01-03 Academia Sinica The capture, purification and release of biological substance using a surface coating
CN103842813B (zh) * 2011-09-06 2018-04-17 贝克顿·迪金森公司 用于对样品中的稀少目标细胞进行细胞计数检测的方法和组合物
WO2014147631A1 (en) 2013-03-22 2014-09-25 Natco Pharma Limited Formulation comprising gefitinib as oral suspension
EP3126814B1 (en) 2014-04-01 2019-06-12 Academia Sinica Methods and systems for cancer diagnosis and prognosis
US10112198B2 (en) 2014-08-26 2018-10-30 Academia Sinica Collector architecture layout design
JP7057668B2 (ja) * 2014-09-18 2022-04-20 アドナーゲン ゲーエムベーハー 治療剤に対する抵抗性の診断に使用するためのERCC1アイソフォーム3のmRNAおよび/またはタンパク質ならびにこのmRNAおよび/またはタンパク質を使用する治療剤に対する抵抗性を診断するための方法
US10107726B2 (en) 2016-03-16 2018-10-23 Cellmax, Ltd. Collection of suspended cells using a transferable membrane
CN109991410B (zh) * 2017-12-29 2022-07-05 上海白泽医学检验所有限公司 一种含抗cd45单抗的组合物及其使用方法
CN114487059B (zh) * 2021-12-29 2022-11-25 苏州大学 一种电化学发光免疫传感器及其制备和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991005264A1 (en) * 1989-09-29 1991-04-18 Oncogenetics Partners Detection and quantification of neu related proteins in the biological fluids of humans
CA2223027A1 (en) * 1995-06-07 1996-12-19 Igen, Inc. Electrochemiluminescent enzyme immunoassay
WO2000047998A1 (en) * 1999-02-10 2000-08-17 Cell Works Inc. Class characterization of circulating cancer cells isolated from body fluids and methods of use
US7537938B2 (en) 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
EP1360496A4 (en) 2001-02-16 2005-03-09 Immunivest Corp METHOD AND REAGENTS FOR THE QUICK AND EFFICIENT INSULATION OF CIRCULATING CANCER CELLS
CA2465274A1 (en) * 2001-10-26 2003-05-01 Immunivest Corporation Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample
DE60331310D1 (de) * 2002-06-26 2010-04-01 Univ Louisville Res Found Verfahren zum apoptosenachweis
EP2263691B1 (en) 2002-07-15 2012-08-29 F.Hoffmann-La Roche Ag Treatment of cancer with the recombinant humanized monoclonal anti-erbb2 antibody 2C4 (rhuMAb 2C4)
WO2004087887A2 (en) * 2003-04-01 2004-10-14 Monogram Biosciences, Inc. Intracellular complexes as biomarkers
EP1668360A4 (en) * 2003-08-15 2007-08-08 Univ Pittsburgh MULTI FACTOR CANCER DETECTION TEST
ES2553264T3 (es) * 2004-05-27 2015-12-07 The Regents Of The University Of Colorado Métodos para la predicción del resultado clínico para inhibidores del receptor del factor de crecimiento epidérmico para pacientes de cáncer
EP1799857B1 (en) 2004-09-14 2013-11-06 John Wayne Cancer Institute Detection of cancer cells in body fluids
JP4798801B2 (ja) 2004-10-06 2011-10-19 ウェルスタット バイオロジクス コーポレイション 循環する癌細胞におけるHer−2/neuタンパク質のレベルの上昇の検出および処置

Also Published As

Publication number Publication date
EP2008102A2 (en) 2008-12-31
MX2008013332A (es) 2008-11-10
WO2007121465B1 (en) 2008-09-12
WO2007121465A3 (en) 2008-06-19
US8012480B2 (en) 2011-09-06
JP2009534667A (ja) 2009-09-24
JP5025724B2 (ja) 2012-09-12
EP2008102A4 (en) 2009-07-08
US20090098138A1 (en) 2009-04-16
WO2007121465A2 (en) 2007-10-25

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Effective date: 20140422