CA2635316A1 - Radiation applicator and method of radiating tissue - Google Patents
Radiation applicator and method of radiating tissue Download PDFInfo
- Publication number
- CA2635316A1 CA2635316A1 CA002635316A CA2635316A CA2635316A1 CA 2635316 A1 CA2635316 A1 CA 2635316A1 CA 002635316 A CA002635316 A CA 002635316A CA 2635316 A CA2635316 A CA 2635316A CA 2635316 A1 CA2635316 A1 CA 2635316A1
- Authority
- CA
- Canada
- Prior art keywords
- ferrule
- microwave applicator
- sleeve
- dipole microwave
- inner conductor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/02—Radiation therapy using microwaves
- A61N5/04—Radiators for near-field treatment
- A61N5/045—Radiators for near-field treatment specially adapted for treatment inside the body
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00059—Material properties
- A61B2018/00071—Electrical conductivity
- A61B2018/00077—Electrical conductivity high, i.e. electrically conducting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00059—Material properties
- A61B2018/00071—Electrical conductivity
- A61B2018/00083—Electrical conductivity low, i.e. electrically insulating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00172—Connectors and adapters therefor
- A61B2018/00178—Electrical connectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/183—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves characterised by the type of antenna
- A61B2018/1838—Dipole antennas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/1869—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument interstitially inserted into the body, e.g. needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/1892—Details of electrical isolations of the antenna
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Electromagnetism (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Plasma & Fusion (AREA)
- Computer Vision & Pattern Recognition (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Surgical Instruments (AREA)
- Radiation-Therapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0600018.6 | 2006-01-03 | ||
| GB0600018A GB2434314B (en) | 2006-01-03 | 2006-01-03 | Microwave applicator with dipole antenna |
| PCT/EP2006/012144 WO2007076924A2 (en) | 2006-01-03 | 2006-12-15 | Radiation applicator and method of radiating tissue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2635316A1 true CA2635316A1 (en) | 2007-07-12 |
Family
ID=35841437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002635316A Abandoned CA2635316A1 (en) | 2006-01-03 | 2006-12-15 | Radiation applicator and method of radiating tissue |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20080294155A1 (enExample) |
| EP (1) | EP1968469B8 (enExample) |
| JP (1) | JP5318581B2 (enExample) |
| KR (1) | KR20080092402A (enExample) |
| CN (1) | CN101631506B (enExample) |
| AU (1) | AU2006332213B2 (enExample) |
| BR (1) | BRPI0620875A2 (enExample) |
| CA (1) | CA2635316A1 (enExample) |
| GB (1) | GB2434314B (enExample) |
| IL (1) | IL192469A0 (enExample) |
| TW (1) | TW200740407A (enExample) |
| WO (1) | WO2007076924A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023180355A1 (en) | 2022-03-24 | 2023-09-28 | Huber+Suhner Ag | Cable assembly |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7128739B2 (en) | 2001-11-02 | 2006-10-31 | Vivant Medical, Inc. | High-strength microwave antenna assemblies and methods of use |
| US6878147B2 (en) | 2001-11-02 | 2005-04-12 | Vivant Medical, Inc. | High-strength microwave antenna assemblies |
| GB2403148C2 (en) | 2003-06-23 | 2013-02-13 | Microsulis Ltd | Radiation applicator |
| US7311703B2 (en) | 2003-07-18 | 2007-12-25 | Vivant Medical, Inc. | Devices and methods for cooling microwave antennas |
| GB2415630C2 (en) | 2004-07-02 | 2007-03-22 | Microsulis Ltd | Radiation applicator and method of radiating tissue |
| US7799019B2 (en) * | 2005-05-10 | 2010-09-21 | Vivant Medical, Inc. | Reinforced high strength microwave antenna |
| US7826904B2 (en) | 2006-02-07 | 2010-11-02 | Angiodynamics, Inc. | Interstitial microwave system and method for thermal treatment of diseases |
| EP3797721A1 (en) | 2006-03-24 | 2021-03-31 | Neuwave Medical, Inc. | Transmission line with heat transfer ability |
| US11389235B2 (en) | 2006-07-14 | 2022-07-19 | Neuwave Medical, Inc. | Energy delivery systems and uses thereof |
| US10376314B2 (en) | 2006-07-14 | 2019-08-13 | Neuwave Medical, Inc. | Energy delivery systems and uses thereof |
| GB0624658D0 (en) | 2006-12-11 | 2007-01-17 | Medical Device Innovations Ltd | Electrosurgical ablation apparatus and a method of ablating biological tissue |
| US7998139B2 (en) * | 2007-04-25 | 2011-08-16 | Vivant Medical, Inc. | Cooled helical antenna for microwave ablation |
| US8353901B2 (en) | 2007-05-22 | 2013-01-15 | Vivant Medical, Inc. | Energy delivery conduits for use with electrosurgical devices |
| US9023024B2 (en) | 2007-06-20 | 2015-05-05 | Covidien Lp | Reflective power monitoring for microwave applications |
| US20090005766A1 (en) * | 2007-06-28 | 2009-01-01 | Joseph Brannan | Broadband microwave applicator |
| US20090082762A1 (en) * | 2007-09-20 | 2009-03-26 | Ormsby Theodore C | Radio frequency energy transmission device for the ablation of biological tissues |
| US8221409B2 (en) * | 2007-12-21 | 2012-07-17 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Thermally insulated irrigation catheter assembly |
| US8945111B2 (en) | 2008-01-23 | 2015-02-03 | Covidien Lp | Choked dielectric loaded tip dipole microwave antenna |
| US8965536B2 (en) | 2008-03-03 | 2015-02-24 | Covidien Lp | Intracooled percutaneous microwave ablation probe |
| US9198723B2 (en) | 2008-03-31 | 2015-12-01 | Covidien Lp | Re-hydration antenna for ablation |
| US8059059B2 (en) * | 2008-05-29 | 2011-11-15 | Vivant Medical, Inc. | Slidable choke microwave antenna |
| US8251987B2 (en) | 2008-08-28 | 2012-08-28 | Vivant Medical, Inc. | Microwave antenna |
| US8403924B2 (en) | 2008-09-03 | 2013-03-26 | Vivant Medical, Inc. | Shielding for an isolation apparatus used in a microwave generator |
| US8394086B2 (en) * | 2008-09-03 | 2013-03-12 | Vivant Medical, Inc. | Microwave shielding apparatus |
| US9113924B2 (en) | 2008-10-17 | 2015-08-25 | Covidien Lp | Choked dielectric loaded tip dipole microwave antenna |
| US8118808B2 (en) | 2009-03-10 | 2012-02-21 | Vivant Medical, Inc. | Cooled dielectrically buffered microwave dipole antenna |
| US8632534B2 (en) | 2009-04-03 | 2014-01-21 | Angiodynamics, Inc. | Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD) |
| US10022202B2 (en) | 2013-03-15 | 2018-07-17 | Triagenics, Llc | Therapeutic tooth bud ablation |
| EP2429444B1 (en) | 2009-05-11 | 2024-02-28 | TriAgenics, Inc. | Therapeutic tooth bud ablation |
| WO2014143014A1 (en) | 2013-03-15 | 2014-09-18 | Triagenics, Llc | Therapeutic tooth bud ablation |
| WO2010138919A2 (en) | 2009-05-28 | 2010-12-02 | Angiodynamics, Inc. | System and method for synchronizing energy delivery to the cardiac rhythm |
| US9895189B2 (en) | 2009-06-19 | 2018-02-20 | Angiodynamics, Inc. | Methods of sterilization and treating infection using irreversible electroporation |
| WO2011017168A2 (en) | 2009-07-28 | 2011-02-10 | Neuwave Medical, Inc. | Energy delivery systems and uses thereof |
| US8328801B2 (en) * | 2009-08-17 | 2012-12-11 | Vivant Medical, Inc. | Surface ablation antenna with dielectric loading |
| TWI397399B (zh) * | 2009-08-26 | 2013-06-01 | Univ Nat Cheng Kung | 兩段式電磁熱療法治療裝置 |
| US9113925B2 (en) * | 2009-09-09 | 2015-08-25 | Covidien Lp | System and method for performing an ablation procedure |
| US8069553B2 (en) * | 2009-09-09 | 2011-12-06 | Vivant Medical, Inc. | Method for constructing a dipole antenna |
| US8568398B2 (en) | 2009-09-29 | 2013-10-29 | Covidien Lp | Flow rate monitor for fluid cooled microwave ablation probe |
| US9113926B2 (en) | 2009-09-29 | 2015-08-25 | Covidien Lp | Management of voltage standing wave ratio at skin surface during microwave ablation |
| GB2474233A (en) | 2009-10-06 | 2011-04-13 | Uk Investments Associates Llc | Cooling pump comprising a detachable head portion |
| US9993294B2 (en) * | 2009-11-17 | 2018-06-12 | Perseon Corporation | Microwave coagulation applicator and system with fluid injection |
| US8551083B2 (en) | 2009-11-17 | 2013-10-08 | Bsd Medical Corporation | Microwave coagulation applicator and system |
| US8882759B2 (en) | 2009-12-18 | 2014-11-11 | Covidien Lp | Microwave ablation system with dielectric temperature probe |
| KR101173455B1 (ko) | 2010-01-26 | 2012-08-14 | 서울대학교산학협력단 | 복수의 서로 다른 크기의 슬롯을 구비한 어플리케이터 |
| US8568404B2 (en) | 2010-02-19 | 2013-10-29 | Covidien Lp | Bipolar electrode probe for ablation monitoring |
| EP2563256B1 (en) | 2010-04-26 | 2019-08-28 | Medtronic Holding Company Sàrl | Electrosurgical device |
| US12076074B2 (en) | 2010-04-26 | 2024-09-03 | Medtronic Holding Company Sàrl | Electrosurgical device and methods |
| ES2856026T3 (es) | 2010-05-03 | 2021-09-27 | Neuwave Medical Inc | Sistemas de suministro de energía |
| US8740893B2 (en) | 2010-06-30 | 2014-06-03 | Covidien Lp | Adjustable tuning of a dielectrically loaded loop antenna |
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| US9770294B2 (en) | 2011-01-05 | 2017-09-26 | Covidien Lp | Energy-delivery devices with flexible fluid-cooled shaft, inflow/outflow junctions suitable for use with same, and systems including same |
| US8932281B2 (en) * | 2011-01-05 | 2015-01-13 | Covidien Lp | Energy-delivery devices with flexible fluid-cooled shaft, inflow/outflow junctions suitable for use with same, and systems including same |
| US9011421B2 (en) * | 2011-01-05 | 2015-04-21 | Covidien Lp | Energy-delivery devices with flexible fluid-cooled shaft, inflow/outflow junctions suitable for use with same, and systems including same |
| US9017319B2 (en) | 2011-01-05 | 2015-04-28 | Covidien Lp | Energy-delivery devices with flexible fluid-cooled shaft, inflow/outflow junctions suitable for use with same, and systems including same |
| US9198724B2 (en) | 2011-04-08 | 2015-12-01 | Covidien Lp | Microwave tissue dissection and coagulation |
| US20120310230A1 (en) * | 2011-06-01 | 2012-12-06 | Angiodynamics, Inc. | Coaxial dual function probe and method of use |
| US9078665B2 (en) | 2011-09-28 | 2015-07-14 | Angiodynamics, Inc. | Multiple treatment zone ablation probe |
| US9192438B2 (en) | 2011-12-21 | 2015-11-24 | Neuwave Medical, Inc. | Energy delivery systems and uses thereof |
| US9414881B2 (en) | 2012-02-08 | 2016-08-16 | Angiodynamics, Inc. | System and method for increasing a target zone for electrical ablation |
| US9095360B2 (en) | 2012-04-06 | 2015-08-04 | Wisconsin Alumni Research Foundation | Feeding structure for dual slot microwave ablation probe |
| US9529025B2 (en) | 2012-06-29 | 2016-12-27 | Covidien Lp | Systems and methods for measuring the frequency of signals generated by high frequency medical devices |
| US9901398B2 (en) | 2012-06-29 | 2018-02-27 | Covidien Lp | Microwave antenna probes |
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| WO2014047355A1 (en) | 2012-09-19 | 2014-03-27 | Denervx LLC | Cooled microwave denervation |
| US9901399B2 (en) * | 2012-12-17 | 2018-02-27 | Covidien Lp | Ablation probe with tissue sensing configuration |
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| AU2014229253B2 (en) | 2013-03-15 | 2018-10-04 | Medtronic Holding Company Sàrl | Electrosurgical mapping tools and methods |
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| US9655670B2 (en) | 2013-07-29 | 2017-05-23 | Covidien Lp | Systems and methods for measuring tissue impedance through an electrosurgical cable |
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| CN104905874A (zh) * | 2015-06-16 | 2015-09-16 | 翟博 | 一种具有活检功能的微波消融针及其刺头的制造方法 |
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| CN108366820B (zh) | 2015-10-26 | 2021-04-02 | 纽韦弗医疗设备公司 | 能量递送系统及其用途 |
| US10441339B2 (en) | 2015-11-17 | 2019-10-15 | Medtronic Holding Company Sárl | Spinal tissue ablation apparatus, system, and method |
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| CN112638300B (zh) * | 2018-07-19 | 2024-05-31 | 悉尼大学 | 消融病变装置 |
| EP3695798A1 (en) * | 2019-02-13 | 2020-08-19 | National University of Ireland Galway | An ablation probe |
| US11832879B2 (en) | 2019-03-08 | 2023-12-05 | Neuwave Medical, Inc. | Systems and methods for energy delivery |
| EP4413935A3 (en) * | 2019-06-06 | 2024-09-18 | TriAgenics, Inc. | Ablation probe systems |
| US11737824B2 (en) * | 2019-08-07 | 2023-08-29 | Biocompatibles Uk Limited | Microwave ablation probe |
| US12226143B2 (en) | 2020-06-22 | 2025-02-18 | Covidien Lp | Universal surgical footswitch toggling |
| USD1084316S1 (en) | 2023-11-20 | 2025-07-15 | Angiodynamics, Inc. | Ferrule |
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2006
- 2006-01-03 GB GB0600018A patent/GB2434314B/en not_active Expired - Fee Related
- 2006-12-15 KR KR1020087019019A patent/KR20080092402A/ko not_active Ceased
- 2006-12-15 BR BRPI0620875-4A patent/BRPI0620875A2/pt not_active IP Right Cessation
- 2006-12-15 WO PCT/EP2006/012144 patent/WO2007076924A2/en not_active Ceased
- 2006-12-15 JP JP2008547872A patent/JP5318581B2/ja active Active
- 2006-12-15 EP EP06829673.0A patent/EP1968469B8/en active Active
- 2006-12-15 AU AU2006332213A patent/AU2006332213B2/en not_active Ceased
- 2006-12-15 CN CN2006800502779A patent/CN101631506B/zh not_active Expired - Fee Related
- 2006-12-15 CA CA002635316A patent/CA2635316A1/en not_active Abandoned
- 2006-12-15 US US12/158,831 patent/US20080294155A1/en not_active Abandoned
- 2006-12-18 TW TW095147386A patent/TW200740407A/zh unknown
- 2006-12-27 US US11/646,141 patent/US20070203551A1/en not_active Abandoned
-
2008
- 2008-06-26 IL IL192469A patent/IL192469A0/en unknown
-
2015
- 2015-11-13 US US14/940,354 patent/US9907613B2/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023180355A1 (en) | 2022-03-24 | 2023-09-28 | Huber+Suhner Ag | Cable assembly |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1968469A2 (en) | 2008-09-17 |
| JP5318581B2 (ja) | 2013-10-16 |
| GB2434314A (en) | 2007-07-25 |
| CN101631506A (zh) | 2010-01-20 |
| JP2009521967A (ja) | 2009-06-11 |
| US20070203551A1 (en) | 2007-08-30 |
| WO2007076924A3 (en) | 2007-08-30 |
| WO2007076924A2 (en) | 2007-07-12 |
| CN101631506B (zh) | 2011-12-28 |
| AU2006332213B2 (en) | 2013-01-10 |
| TW200740407A (en) | 2007-11-01 |
| US20080294155A1 (en) | 2008-11-27 |
| KR20080092402A (ko) | 2008-10-15 |
| BRPI0620875A2 (pt) | 2011-11-29 |
| GB2434314B (en) | 2011-06-15 |
| EP1968469B1 (en) | 2016-11-02 |
| US20160262832A1 (en) | 2016-09-15 |
| EP1968469B8 (en) | 2017-01-11 |
| US9907613B2 (en) | 2018-03-06 |
| GB0600018D0 (en) | 2006-02-08 |
| AU2006332213A1 (en) | 2007-07-12 |
| IL192469A0 (en) | 2009-02-11 |
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