CA2630262C - The use of isothiocyanates compounds in treating prostatic diseases and skin cancer - Google Patents

The use of isothiocyanates compounds in treating prostatic diseases and skin cancer Download PDF

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Publication number
CA2630262C
CA2630262C CA2630262A CA2630262A CA2630262C CA 2630262 C CA2630262 C CA 2630262C CA 2630262 A CA2630262 A CA 2630262A CA 2630262 A CA2630262 A CA 2630262A CA 2630262 C CA2630262 C CA 2630262C
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CA
Canada
Prior art keywords
peitc
isothiocyanates
oil
isothiocyanate
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2630262A
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English (en)
French (fr)
Other versions
CA2630262A1 (en
Inventor
Jingcai Cheng
Jenwei Chiao
Haiya Jin
Chengjuan Zhong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuxi JC Pharmaceutical Tech Co Ltd
Original Assignee
Wuxi JC Pharmaceutical Tech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 200510095737 external-priority patent/CN1769268A/zh
Priority claimed from CNA2006100381121A external-priority patent/CN1840196A/zh
Application filed by Wuxi JC Pharmaceutical Tech Co Ltd filed Critical Wuxi JC Pharmaceutical Tech Co Ltd
Publication of CA2630262A1 publication Critical patent/CA2630262A1/en
Application granted granted Critical
Publication of CA2630262C publication Critical patent/CA2630262C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA2630262A 2005-11-15 2006-11-14 The use of isothiocyanates compounds in treating prostatic diseases and skin cancer Active CA2630262C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN 200510095737 CN1769268A (zh) 2005-11-15 2005-11-15 一种天然及人工合成的异硫氰酸酯类化合物jc-5411在制备转录因子sp1的抑制剂中的应用
CN200510095737.7 2005-11-15
CN200610038112.1 2006-01-27
CNA2006100381121A CN1840196A (zh) 2006-01-27 2006-01-27 一种适用于难溶性药物的分散剂
PCT/CN2006/003062 WO2007056941A1 (fr) 2005-11-15 2006-11-14 Utilisation de composes a base d'isothiocyanates dans le traitement de maladies prostatiques et du cancer de la peau

Publications (2)

Publication Number Publication Date
CA2630262A1 CA2630262A1 (en) 2007-05-24
CA2630262C true CA2630262C (en) 2011-11-08

Family

ID=38048290

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2630262A Active CA2630262C (en) 2005-11-15 2006-11-14 The use of isothiocyanates compounds in treating prostatic diseases and skin cancer

Country Status (7)

Country Link
US (2) US8039511B2 (de)
EP (2) EP1961418B1 (de)
JP (1) JP5308160B2 (de)
AT (1) ATE552000T1 (de)
CA (1) CA2630262C (de)
DK (2) DK1961418T3 (de)
WO (1) WO2007056941A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8665785B2 (en) * 2009-09-11 2014-03-04 Enversa Companies, Llc Systems and methods for establishing a telecommunications bridge between a user device and a node
CN102160872A (zh) * 2010-02-23 2011-08-24 天津天士力制药股份有限公司 复方丹参滴丸胶囊
US8414869B2 (en) * 2010-11-30 2013-04-09 N.V. Perricone Llc Melanin promoting topical composition
US11279674B2 (en) 2011-01-03 2022-03-22 The William M. Yarbrough Foundation Isothiocyanate functional surfactant and associated method of use
US8933119B2 (en) 2011-01-03 2015-01-13 The William M. Yarbrough Foundation Method for treating phytophotodermatitis
US9962361B2 (en) 2011-01-03 2018-05-08 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
US10308599B2 (en) 2011-01-03 2019-06-04 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
US10647668B2 (en) 2011-01-03 2020-05-12 The William M. Yarbrough Foundation Isothiocyanate functional surfactant and associated method of use
US11407713B2 (en) 2011-01-03 2022-08-09 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
US10273205B2 (en) 2011-01-03 2019-04-30 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms
US10640464B2 (en) 2011-01-03 2020-05-05 The William M. Yarbrough Foundation Use of isothiocyanate functional surfactants as Nrf2 inducers to treat epidermolysis bullosa simplex and related diseases
US8865765B2 (en) 2011-01-12 2014-10-21 The William M. Yarbrough Foundation Method for treating eczema
US9532969B2 (en) 2011-02-08 2017-01-03 The William M. Yarbrough Foundation Method for treating psoriasis
WO2014018874A1 (en) 2012-07-26 2014-01-30 The William M. Yarbrough Foundation Method for treating skin cancer
US10434081B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Inhibitors of macrophage migration inhibitory factor
US10080734B2 (en) 2012-07-26 2018-09-25 The William M. Yarbrough Foundation Method for treating autism and other neurodevelopmental disorders
US10434082B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms
US9949943B2 (en) 2012-07-26 2018-04-24 The William M. Yarbrough Foundation Method for treating neurodegenerative diseases
US10441561B2 (en) 2012-07-26 2019-10-15 The William M. Yanbrough Foundation Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer
US10335387B2 (en) 2012-07-26 2019-07-02 The William M. Yarbrough Foundation Method for treating infectious diseases with isothiocyanate functional compounds
US9839621B2 (en) 2012-07-26 2017-12-12 The William M. Yarbrough Foundation Method for treating bladder cancer
TWI495464B (zh) * 2013-02-08 2015-08-11 Univ Nat Taiwan 苦味化合物於活化glp-1分泌之用途
US10010520B2 (en) 2013-08-13 2018-07-03 Jc (Wuxi) Company, Inc. Combined application of isothiocyanate compound and anti-cancer medicine
US20160361380A1 (en) * 2015-06-12 2016-12-15 Nymox Corporation Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations
BR112020005006A2 (pt) * 2017-09-15 2020-09-15 Tyme, Inc. formulações transdérmicas
DE102018121251A1 (de) * 2018-08-30 2020-03-05 Shenstone Consultants Ltd. Isothiocyanate
MX2021013901A (es) 2019-05-14 2022-04-12 Tyme Inc Composiciones y métodos para el tratamiento del cáncer.
EP3996670A4 (de) * 2019-07-10 2023-08-30 Nanometics LLC (D.B.A. Phd Biosciences) Polyurethangele
JP2022546090A (ja) 2019-08-30 2022-11-02 グラント インダストリーズ,インコーポレーテッド 化粧品及びパーソナルケアのためのバイオベース及び生分解性のエラストマー
IT201900025840A1 (it) * 2019-12-31 2021-07-01 Univ Bologna Alma Mater Studiorum Composti isotiocianati e isoselencianati
US10905698B1 (en) 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003294778A1 (en) * 2002-12-06 2004-06-30 Dsm Ip Assets B.V. Novel use of lycopene
US20050070602A1 (en) * 2003-09-30 2005-03-31 Jen-Wei Chiao Method of modulating immune response by administration of immuno-activation agent
CN100448845C (zh) * 2005-06-30 2009-01-07 无锡杰西医药科技有限公司 一种天然及人工合成的异硫氰酸酯类化合物jc-5411在制备预防和治疗前列腺癌、肝癌、胃癌、肺癌、乳腺癌、宫颈癌、黑色素瘤和神经母细胞瘤的药物中的应用
EP2083840A4 (de) * 2006-10-17 2012-01-25 Summa Dev Ltd Verbesserte behandlung für benigne prostatahyperplasie

Also Published As

Publication number Publication date
DK2441454T3 (en) 2015-12-21
US20120046358A1 (en) 2012-02-23
EP1961418B1 (de) 2012-04-04
EP1961418A1 (de) 2008-08-27
ATE552000T1 (de) 2012-04-15
JP5308160B2 (ja) 2013-10-09
US8410170B2 (en) 2013-04-02
US8039511B2 (en) 2011-10-18
CA2630262A1 (en) 2007-05-24
US20090005438A1 (en) 2009-01-01
EP2441454A1 (de) 2012-04-18
EP1961418A4 (de) 2009-09-02
WO2007056941A1 (fr) 2007-05-24
JP2009515910A (ja) 2009-04-16
EP2441454B1 (de) 2015-09-16
DK1961418T3 (da) 2012-07-23

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