CA2629196A1 - 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations - Google Patents
17-allylamino-17-demethoxygeldanamycin polymorphs and formulations Download PDFInfo
- Publication number
- CA2629196A1 CA2629196A1 CA002629196A CA2629196A CA2629196A1 CA 2629196 A1 CA2629196 A1 CA 2629196A1 CA 002629196 A CA002629196 A CA 002629196A CA 2629196 A CA2629196 A CA 2629196A CA 2629196 A1 CA2629196 A1 CA 2629196A1
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- Prior art keywords
- aag
- polymorph
- purified
- particle size
- suspension formulation
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73922505P | 2005-11-23 | 2005-11-23 | |
| US60/739,225 | 2005-11-23 | ||
| US80952706P | 2006-05-30 | 2006-05-30 | |
| US60/809,527 | 2006-05-30 | ||
| US11/595,005 US7648976B2 (en) | 2005-11-23 | 2006-11-08 | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
| US11/595,005 | 2006-11-08 | ||
| PCT/US2006/044746 WO2007061878A2 (en) | 2005-11-23 | 2006-11-16 | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2629196A1 true CA2629196A1 (en) | 2007-05-31 |
Family
ID=38067791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002629196A Abandoned CA2629196A1 (en) | 2005-11-23 | 2006-11-16 | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7648976B2 (enExample) |
| EP (1) | EP1951223A4 (enExample) |
| JP (1) | JP2009517386A (enExample) |
| KR (1) | KR20080089357A (enExample) |
| AU (1) | AU2006318771A1 (enExample) |
| BR (1) | BRPI0618873A2 (enExample) |
| CA (1) | CA2629196A1 (enExample) |
| WO (1) | WO2007061878A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090042847A1 (en) * | 2005-11-23 | 2009-02-12 | Kosan Biosciences Incorporated | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
| US20070167422A1 (en) * | 2006-01-18 | 2007-07-19 | Yu Kwok S | Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin |
| GB0612928D0 (en) * | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
| EP2121957A4 (en) * | 2007-01-26 | 2010-11-10 | Kosan Biosciences Inc | MACROLACTAMES OBTAINED BY MODIFIED BIOSYNTHESIS |
| US20090258869A1 (en) * | 2008-02-08 | 2009-10-15 | The Regents Of The University Of California | Methods and compounds for treatment or prevention of substance-related disorders |
| CA3030142A1 (en) * | 2016-07-08 | 2018-01-11 | Ranedis Pharmaceuticals, Llc | Compositions and methods of treating and/or preventing lysosomal storage diseases and other monogenetic metabolic diseases |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4261989A (en) | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| US5932566A (en) | 1994-06-16 | 1999-08-03 | Pfizer Inc. | Ansamycin derivatives as antioncogene and anticancer agents |
| US5662883A (en) | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
| US5534270A (en) | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
| US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US6682758B1 (en) | 1998-12-22 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | Water-insoluble drug delivery system |
| EP1373215B1 (en) | 2001-03-30 | 2006-07-26 | THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH | Geldanamycin derivatives useful for treating cancer |
| US20040138160A1 (en) | 2001-04-27 | 2004-07-15 | Kenichiro Naito | Preventive/therapeutic method for cancer |
| US6872715B2 (en) | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| DE60225307T2 (de) | 2001-09-24 | 2009-03-19 | Conforma Therapeutics Corp., San Diego | Verfahren zur herstellung von 17-allyl-amino-geldanamycin (17-aag) und anderer ansamycine |
| JP2005528390A (ja) | 2002-04-10 | 2005-09-22 | コンフォーマ・セラピューティクス・コーポレイション | アンサマイシン製剤およびその製造ならびに使用方法 |
| US20060148776A1 (en) | 2003-03-13 | 2006-07-06 | Conforma Therapeutics Corporation | Drug formulations having long and medium chain triglycerides |
| US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| US20050020557A1 (en) | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors |
| US20050054625A1 (en) | 2003-05-30 | 2005-03-10 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with nuclear export inhibitors |
| US7691838B2 (en) | 2003-05-30 | 2010-04-06 | Kosan Biosciences Incorporated | Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics |
| US20050054589A1 (en) | 2003-05-30 | 2005-03-10 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with antibiotics |
| US20050026893A1 (en) | 2003-05-30 | 2005-02-03 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants |
| US20050020534A1 (en) | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites |
| US20050020556A1 (en) | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes |
| US6887993B1 (en) | 2003-11-12 | 2005-05-03 | Kosan Biosciences, Inc. | 11-O-methylgeldanamycin compounds |
| US20050256097A1 (en) | 2004-05-11 | 2005-11-17 | Kosan Biosciences, Inc. | Pharmaceutical solution formulations containing 17-AAG |
| WO2006034147A2 (en) | 2004-09-16 | 2006-03-30 | Abraxis Bioscience, Inc. | Compositions and methods for the preparation and administration of poorly water soluble drugs |
| US20060067953A1 (en) | 2004-09-29 | 2006-03-30 | Conforma Therapeutics Corporation | Oral pharmaceutical formulations and methods for producing and using same |
| CA2596867A1 (en) | 2005-02-28 | 2006-09-08 | Kosan Biosciences Incorporated | Pharmaceutical formulations containing 17-allylamino-17-demethoxygeldanamycin |
| US20060228405A1 (en) * | 2005-04-07 | 2006-10-12 | Conforma Therapeutics Corporation | Phospholipid-based pharmaceutical formulations and methods for producing and using same |
-
2006
- 2006-11-08 US US11/595,005 patent/US7648976B2/en not_active Expired - Fee Related
- 2006-11-16 JP JP2008542377A patent/JP2009517386A/ja not_active Abandoned
- 2006-11-16 KR KR1020087015304A patent/KR20080089357A/ko not_active Withdrawn
- 2006-11-16 CA CA002629196A patent/CA2629196A1/en not_active Abandoned
- 2006-11-16 BR BRPI0618873A patent/BRPI0618873A2/pt not_active IP Right Cessation
- 2006-11-16 WO PCT/US2006/044746 patent/WO2007061878A2/en not_active Ceased
- 2006-11-16 EP EP06837958A patent/EP1951223A4/en not_active Withdrawn
- 2006-11-16 AU AU2006318771A patent/AU2006318771A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009517386A (ja) | 2009-04-30 |
| EP1951223A2 (en) | 2008-08-06 |
| US20070203110A1 (en) | 2007-08-30 |
| AU2006318771A1 (en) | 2007-05-31 |
| WO2007061878A3 (en) | 2009-06-04 |
| EP1951223A4 (en) | 2010-04-21 |
| US7648976B2 (en) | 2010-01-19 |
| BRPI0618873A2 (pt) | 2016-09-06 |
| WO2007061878A2 (en) | 2007-05-31 |
| KR20080089357A (ko) | 2008-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20121116 |