CA2627430C - Growth control of oral and superficial microorganisms using gallium compounds - Google Patents

Growth control of oral and superficial microorganisms using gallium compounds Download PDF

Info

Publication number
CA2627430C
CA2627430C CA2627430A CA2627430A CA2627430C CA 2627430 C CA2627430 C CA 2627430C CA 2627430 A CA2627430 A CA 2627430A CA 2627430 A CA2627430 A CA 2627430A CA 2627430 C CA2627430 C CA 2627430C
Authority
CA
Canada
Prior art keywords
gallium
microorganisms
infections
compounds
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2627430A
Other languages
English (en)
French (fr)
Other versions
CA2627430A1 (en
Inventor
Daniel P. Perl
Sharon Moalem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icahn School of Medicine at Mount Sinai
Original Assignee
Mount Sinai School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mount Sinai School of Medicine filed Critical Mount Sinai School of Medicine
Priority to CA2784168A priority Critical patent/CA2784168C/en
Publication of CA2627430A1 publication Critical patent/CA2627430A1/en
Application granted granted Critical
Publication of CA2627430C publication Critical patent/CA2627430C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • A01N55/02Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/70Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/788Inorganic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/088Heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18Liquid substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A61Q11/02Preparations for deodorising, bleaching or disinfecting dentures
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/58Metal complex; Coordination compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/224Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials containing metals, e.g. porphyrins, vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Wood Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Emergency Medicine (AREA)
  • Animal Husbandry (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
CA2627430A 2005-11-01 2006-10-31 Growth control of oral and superficial microorganisms using gallium compounds Expired - Fee Related CA2627430C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2784168A CA2784168C (en) 2005-11-01 2006-10-31 Growth control of oral and superficial microorganisms using gallium compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73187505P 2005-11-01 2005-11-01
US60/731,875 2005-11-01
PCT/US2006/042381 WO2007053581A2 (en) 2005-11-01 2006-10-31 Growth control of oral and superficial microorganisms using gallium compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2784168A Division CA2784168C (en) 2005-11-01 2006-10-31 Growth control of oral and superficial microorganisms using gallium compounds

Publications (2)

Publication Number Publication Date
CA2627430A1 CA2627430A1 (en) 2007-05-10
CA2627430C true CA2627430C (en) 2012-10-16

Family

ID=38006451

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2627430A Expired - Fee Related CA2627430C (en) 2005-11-01 2006-10-31 Growth control of oral and superficial microorganisms using gallium compounds
CA2784168A Expired - Fee Related CA2784168C (en) 2005-11-01 2006-10-31 Growth control of oral and superficial microorganisms using gallium compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2784168A Expired - Fee Related CA2784168C (en) 2005-11-01 2006-10-31 Growth control of oral and superficial microorganisms using gallium compounds

Country Status (7)

Country Link
US (3) US20110038809A1 (https=)
EP (2) EP2689783B1 (https=)
JP (2) JP5264494B2 (https=)
KR (2) KR101218854B1 (https=)
CN (2) CN104473962B (https=)
CA (2) CA2627430C (https=)
WO (1) WO2007053581A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104473962B (zh) 2005-11-01 2018-05-01 西奈山医学院 使用镓化合物的口部和表面微生物的生长控制
KR101217415B1 (ko) * 2007-04-02 2013-01-02 사이더로믹스, 엘엘씨 갈륨 화합물을 이용하는 감염성 질환의 예방 및 치료 방법
BE1018018A6 (nl) 2008-02-28 2010-04-06 Gielen Cornelis Oplossing voor het biologisch reinigen van tandenborstels en bijhorende inrichting.
US20140242005A1 (en) 2011-10-05 2014-08-28 Multi Oral Bv Method For Oral Care
CN103974688A (zh) * 2011-12-15 2014-08-06 高露洁-棕榄公司 口腔护理组合物
US20130266629A1 (en) * 2012-03-30 2013-10-10 Dentsply International Inc. Medical device having a surface comprising antimicrobial metal
EP2662051A1 (en) * 2012-05-11 2013-11-13 Dentsply IH AB Medical device having a surface comprising nanoparticles
CA2905788C (en) * 2013-03-12 2022-08-16 Emily A. Stein Dental composition comprising chelator and base
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
WO2019165425A1 (en) * 2018-02-26 2019-08-29 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Antimicrobial gallium compounds and methods
CN109481208A (zh) * 2018-12-21 2019-03-19 南京汉瑞生物科技有限公司 一种应用镓元素的医疗护理设备
JP7271341B2 (ja) * 2019-06-28 2023-05-11 サンスター スイス エスエー 歯周病進行リスク測定方法及びキット
CN111719196A (zh) * 2020-07-31 2020-09-29 储旭 复合抗菌纤维及其制备方法
CN111876879A (zh) * 2020-07-31 2020-11-03 储旭 抗菌面料及其制备方法
CN113600827B (zh) * 2021-07-30 2022-07-19 山东大学 一种Au/Ga2O3/AuGa2多相复合材料及其制备方法与应用
CN115024391A (zh) * 2022-06-27 2022-09-09 广东粤港澳大湾区国家纳米科技创新研究院 一种抗菌饲料添加剂及其制备方法以及应用
CN117257955B (zh) * 2023-11-17 2024-03-15 深圳大学 铁氧还蛋白还原酶Fpr作为绿脓杆菌治疗药物靶点的应用

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB654472A (en) * 1947-03-12 1951-06-20 Procter & Gamble Preparations for use in contact with the teeth
US4177475A (en) * 1977-10-31 1979-12-04 Burroughs Corporation High temperature amorphous memory device for an electrically alterable read-only memory
US4203123A (en) * 1977-12-12 1980-05-13 Burroughs Corporation Thin film memory device employing amorphous semiconductor materials
US4388321A (en) * 1981-08-06 1983-06-14 Monsanto Company Method for inhibiting growth of food poisoning organisms
DE3376387D1 (en) 1982-10-22 1988-06-01 Sloan Kettering Inst Cancer The use of gallium salts for the manufacture of pharmaceutical compositions for the treatment of disorders of calcium homeostasis
WO1991006287A1 (en) * 1989-11-06 1991-05-16 Enzytech, Inc. Protein microspheres and methods of using them
US5258376A (en) 1989-11-22 1993-11-02 Bernstein Lawrence R Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
US6004951A (en) 1989-11-22 1999-12-21 Bernstein; Lawrence Richard Administration of gallium complexes of 3-hydroxy-4-pyrones to provide physiologically active gallium levels in a mammalian individual
US5574027A (en) 1989-11-22 1996-11-12 Bernstein; Lawrence R. Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
US5556645A (en) * 1990-01-12 1996-09-17 Bockman; Richard Methods of enhancing wound healing and tissue repair
US5686116A (en) * 1990-01-12 1997-11-11 New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery Methods of enhancing repair, healing and augmentation of bone implants
DE69033606T2 (de) 1990-01-12 2001-04-26 New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery Verfahren zur verbesserung der wundheilung und gewebeerneuerung
GB9009437D0 (en) * 1990-04-26 1990-06-20 Glaxo Group Ltd Chemical compounds
SU1739957A1 (ru) * 1990-06-29 1992-06-15 Н.И.Лебедев, В.В.Степанок и С.Н.Лебедева Способ силосовани зеленых кормов
CA2108008C (en) * 1991-04-10 1999-05-04 Christopher C. Capelli Antimicrobial compositions useful for medical applications
US5286480A (en) * 1992-06-29 1994-02-15 The Procter & Gamble Company Use of N-acetylated amino acid complexes in oral care compositions
US5363329A (en) * 1993-11-10 1994-11-08 Eugeniy Troyan Semiconductor memory device for use in an electrically alterable read-only memory
US5858350A (en) * 1993-12-01 1999-01-12 Marine Polymer Technologies Methods and compositions for poly-β-1→4-N-acetylglucosamine cell therapy system
US5641519A (en) * 1995-05-18 1997-06-24 The Ohio State University Method of treating endotoxic shock employing gallium compounds
AUPN881396A0 (en) * 1996-03-20 1996-04-18 Arnott's Biscuits Limited Enhancement of microbial colonization of the gastrointestinal tract
US5843936A (en) * 1996-06-28 1998-12-01 Bernstein; Lawrence R. Topical administration of azaspiranes to prevent or treat skin conditions associated with hyperproliferation of keratinocytes
US5747482A (en) 1996-07-30 1998-05-05 Bernstein; Lawrence R. Methods and compositions to inhibit keratinocyte proliferation
US6203822B1 (en) * 1996-09-03 2001-03-20 University Of Iowa Research Foundation Gallium-containing compounds for the treatment of infections caused by intracellular pathogens and pathogens causing chronic pulmonary infection
US6066628A (en) * 1997-01-09 2000-05-23 Emory University Non-iron metalloporphyrins and methods of use
CN1092962C (zh) * 1998-01-26 2002-10-23 贾伟 一种减轻骨及骨关节疾病疼痛的药物
US6669399B2 (en) 1999-07-12 2003-12-30 Wedgelock Systems, Ltd. Wedge-lockable removable punch and die bushing in retainer
US6297242B1 (en) * 1999-08-12 2001-10-02 Ortho-Mcneil Pharmaceutical, Inc. N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
US20020068761A1 (en) 1999-10-04 2002-06-06 Bernstein Lawrence R. Gallium complexes of 3-hydroxy-4-pyrones to treat mycobacterial infections
JP2003510362A (ja) * 1999-10-04 2003-03-18 ローレンス・アール・バーンスタイン 細胞内原核生物、dnaウイルス及びレトロウイルスによる感染を治療するための、3−ヒドロキシ−4−ピロンのガリウム錯体
JP2001314181A (ja) * 2000-05-10 2001-11-13 Mi Tec:Kk キレート化合物含有酒類
KR100400411B1 (ko) * 2000-09-09 2003-10-01 주식회사 바이오프로젠 질염 치료용 생균제제
SE521022C2 (sv) * 2001-09-20 2003-09-23 Ellen Ab Mjölksyraproducerande bakterier för användning som probiotiska organismer i vaginan hos människa
US20050100563A1 (en) * 2001-01-26 2005-05-12 Hexamer Don L. Antifungal compositions and methods of treatment therewith
US6506413B1 (en) * 2001-04-30 2003-01-14 Joseph C. Ramaekers Compositions for treating animal diseases and syndromes
US20060073197A1 (en) * 2004-05-20 2006-04-06 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US6507061B1 (en) * 2001-08-31 2003-01-14 Intel Corporation Multiple layer phase-change memory
US6660262B2 (en) * 2001-09-28 2003-12-09 Bovine Health Products, Inc. Broad spectrum antimicrobial compound and treatment
US7151273B2 (en) * 2002-02-20 2006-12-19 Micron Technology, Inc. Silver-selenide/chalcogenide glass stack for resistance variable memory
US6872963B2 (en) * 2002-08-08 2005-03-29 Ovonyx, Inc. Programmable resistance memory element with layered memory material
JP4484468B2 (ja) * 2002-08-20 2010-06-16 株式会社メニコン コンタクトレンズの消毒方法及びそのための消毒液
US8100872B2 (en) * 2002-10-23 2012-01-24 Tyco Healthcare Group Lp Medical dressing containing antimicrobial agent
CA2515424A1 (en) * 2003-02-06 2004-08-26 Bioresponse, Llc The combined use of cruciferous indoles and chelators for the treatment of papillomavirus-related conditions
AU2004296178B2 (en) * 2003-12-04 2011-03-24 The United States Of America As Represented By The Department Of Veterans Affairs Gallium inhibits biofilm formation
ZA200605583B (en) * 2003-12-17 2009-06-24 Titan Pharmaceuticals Inc Use of gallium to treat inflammatory arthritis
CN1695493A (zh) * 2004-05-12 2005-11-16 陕西沃森生物基因技术股份有限公司 富有机镓豆芽的生产方法及应用
CN104473962B (zh) 2005-11-01 2018-05-01 西奈山医学院 使用镓化合物的口部和表面微生物的生长控制
AU2007208169A1 (en) * 2006-01-30 2007-08-02 Lawrence R. Bernstein Use of gallium to treat biofilm-associated infectons
WO2008036787A1 (en) 2006-09-22 2008-03-27 C.R. Bard, Inc. Antimicrobial compositions containing gallium
KR101217415B1 (ko) 2007-04-02 2013-01-02 사이더로믹스, 엘엘씨 갈륨 화합물을 이용하는 감염성 질환의 예방 및 치료 방법

Also Published As

Publication number Publication date
EP1962774B1 (en) 2014-01-01
JP2013049674A (ja) 2013-03-14
EP2689783A3 (en) 2014-08-20
US20110038809A1 (en) 2011-02-17
EP2689783B1 (en) 2018-08-15
EP1962774A4 (en) 2011-03-16
JP5264494B2 (ja) 2013-08-14
CN104473962B (zh) 2018-05-01
CA2784168C (en) 2018-04-10
US10632148B2 (en) 2020-04-28
CN104473962A (zh) 2015-04-01
KR20110042386A (ko) 2011-04-26
KR101218854B1 (ko) 2013-01-09
US20140193520A1 (en) 2014-07-10
WO2007053581A2 (en) 2007-05-10
WO2007053581A3 (en) 2008-12-11
EP1962774A2 (en) 2008-09-03
CA2784168A1 (en) 2007-05-10
KR20080072697A (ko) 2008-08-06
JP2009514861A (ja) 2009-04-09
CA2627430A1 (en) 2007-05-10
CN101484178A (zh) 2009-07-15
US20160113962A1 (en) 2016-04-28
EP2689783A2 (en) 2014-01-29
JP5877776B2 (ja) 2016-03-08

Similar Documents

Publication Publication Date Title
US10632148B2 (en) Growth control of oral and superficial organisms using gallium compounds
JP6890843B2 (ja) 抗菌薬耐性株を含む細胞外微生物により引き起こされる感染症をガリウム化合物を用いて予防または治療する方法
Naik et al. Contaminated tooth brushes–potential threat to oral and general health
Pitten et al. Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic
Pitten et al. Antimicrobial efficacy of antiseptic mouthrinse solutions
Nelson-Filho et al. Evaluation of the contamination and disinfection methods of toothbrushes used by 24-to 48-month-old children
US7026353B2 (en) Inhibition of Gram positive bacteria
Lee et al. Antibacterial effect of electrolyzed water on oral bacteria
Noordin et al. The Effect of probiotic mouthrinse on plaque and gingival inflammation
El-Shamy et al. In vitro antimicrobial effectiveness of vinegar against oral microorganisms: Part I
Al-Ahmad et al. An antimicrobial effect from silver-coated toothbrush heads.
Moneib et al. Correlation between the in vivo and in vitro antimicrobial properties of commercially available mouthwash preparations
EP1883401B1 (en) Anti-microbial agent
Yoo et al. Post-antibiotic effects and post-antibiotic sub-minimal inhibitory concentration effects of chlorhexidine against oral bacteria
Rao et al. Evaluation of effectiveness of home remedies for toothbrush decontamination using vinegar and vinegar with common salt
Darout et al. Survival rate of oral bacteria on toothbrush and Miswak stick
Chen et al. Development of an eco-sustainable formulation against Streptococcus mutans and Candida albicans
CN112999337A (zh) 生物酶消毒液制剂及其制备方法
Aristizábal et al. Development of an Effective Triantibiotic formulation for Enterococcus faecalis in the Treatment of Endodontic Pathology
Chavan et al. Comparing Antibacterial Efficacy of 70% Isopropyl Alcohol and 0.2% Chlorhexidine on Toothbrushes: A Double-blind Randomized Controlled Trial
AU759182B2 (en) Inhibition of gram positive bacteria
Paramita et al. Comparison of the efficacy of two disinfectants for controlling gram-positive bacteria on thermoplastic retainers in dental plaques
Kart The susceptibility of Proteus mirabilis and Enterococcus faecalis to various antimicrobial agents in polymicrobial biofilms formed using a drip flow reactor
Peker et al. Research Article Effectiveness of Alternative Methods for Toothbrush Disinfection: An In Vitro Study

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20211101