CA2626383A1 - Spectrometrie de masse avec guides d'ions multipolaires - Google Patents

Spectrometrie de masse avec guides d'ions multipolaires Download PDF

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Publication number
CA2626383A1
CA2626383A1 CA002626383A CA2626383A CA2626383A1 CA 2626383 A1 CA2626383 A1 CA 2626383A1 CA 002626383 A CA002626383 A CA 002626383A CA 2626383 A CA2626383 A CA 2626383A CA 2626383 A1 CA2626383 A1 CA 2626383A1
Authority
CA
Canada
Prior art keywords
multipole ion
mass
ion
ions
multipole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002626383A
Other languages
English (en)
Other versions
CA2626383C (fr
Inventor
Craig M. Whitehouse
Bruce A. Andrien, Jr.
Erol E. Gulcicek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Revvity Health Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2626383A1 publication Critical patent/CA2626383A1/fr
Application granted granted Critical
Publication of CA2626383C publication Critical patent/CA2626383C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CA2626383A 1998-05-29 1999-05-29 Spectrometrie de masse avec guides d'ions multipolaires Expired - Lifetime CA2626383C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8724698P 1998-05-29 1998-05-29
US60/087,246 1998-05-29
US23594699A 1999-01-22 1999-01-22
US09/235,946 1999-01-22
CA002332534A CA2332534C (fr) 1998-05-29 1999-05-29 Spectrometrie de masse avec guides d'ions multipolaires

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002332534A Division CA2332534C (fr) 1998-05-29 1999-05-29 Spectrometrie de masse avec guides d'ions multipolaires

Publications (2)

Publication Number Publication Date
CA2626383A1 true CA2626383A1 (fr) 1999-12-02
CA2626383C CA2626383C (fr) 2011-07-19

Family

ID=26776766

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2626383A Expired - Lifetime CA2626383C (fr) 1998-05-29 1999-05-29 Spectrometrie de masse avec guides d'ions multipolaires
CA002332534A Expired - Lifetime CA2332534C (fr) 1998-05-29 1999-05-29 Spectrometrie de masse avec guides d'ions multipolaires

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002332534A Expired - Lifetime CA2332534C (fr) 1998-05-29 1999-05-29 Spectrometrie de masse avec guides d'ions multipolaires

Country Status (5)

Country Link
EP (1) EP1090412B1 (fr)
JP (1) JP2002517070A (fr)
AU (1) AU4326599A (fr)
CA (2) CA2626383C (fr)
WO (1) WO1999062101A1 (fr)

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CA2326514A1 (fr) * 2000-01-10 2001-07-10 Mds Inc. Appareil et methode permettant la distinction des especes ionisees non desirees, en spectrometrie de masse, au moyen de dispositifs de reaction et d'impact
US6720554B2 (en) * 2000-07-21 2004-04-13 Mds Inc. Triple quadrupole mass spectrometer with capability to perform multiple mass analysis steps
GB2370685B (en) 2000-11-29 2003-01-22 Micromass Ltd Mass spectrometers and methods of mass spectrometry
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
US6956205B2 (en) 2001-06-15 2005-10-18 Bruker Daltonics, Inc. Means and method for guiding ions in a mass spectrometer
JP3620479B2 (ja) * 2001-07-31 2005-02-16 株式会社島津製作所 イオン蓄積装置におけるイオン選別の方法
WO2003056604A1 (fr) 2001-12-21 2003-07-10 Mds Inc., Doing Business As Mds Sciex Utilisation de formes d'ondes large bande a encoche dans un piege a ions lineaire
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
CA2430531C (fr) * 2002-05-30 2012-01-10 Micromass Limited Spectrometre de masse
US7095013B2 (en) 2002-05-30 2006-08-22 Micromass Uk Limited Mass spectrometer
WO2003102508A1 (fr) 2002-05-31 2003-12-11 Analytica Of Branford, Inc. Spectrometrie de masse a multiples guides ioniques rf segmentes en plusieurs zones de pression
US7034292B1 (en) 2002-05-31 2006-04-25 Analytica Of Branford, Inc. Mass spectrometry with segmented RF multiple ion guides in various pressure regions
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
CN100550275C (zh) * 2003-01-24 2009-10-14 萨莫芬尼根有限责任公司 控制质量分析器中的离子数目
DE10326156B4 (de) * 2003-06-10 2011-12-01 Micromass Uk Ltd. Massenspektrometer mit Gaskollisionszelle und Wechselspannungs- oder HF-Ionenführung mit differentiellen Druckbereichen sowie zugehörige Verfahren zur Massenspektrometrie
US6977371B2 (en) 2003-06-10 2005-12-20 Micromass Uk Limited Mass spectrometer
DE102004014582B4 (de) * 2004-03-25 2009-08-20 Bruker Daltonik Gmbh Ionenoptische Phasenvolumenkomprimierung
JP2005276787A (ja) * 2004-03-26 2005-10-06 Tsutomu Masujima 質量分析装置
US20050242281A1 (en) * 2004-04-30 2005-11-03 Gangqiang Li Unevenly segmented multipole
GB0416288D0 (en) 2004-07-21 2004-08-25 Micromass Ltd Mass spectrometer
JP4848657B2 (ja) * 2005-03-28 2011-12-28 株式会社島津製作所 Ｍｓ／ｍｓ型質量分析装置
GB0506288D0 (en) * 2005-03-29 2005-05-04 Thermo Finnigan Llc Improvements relating to mass spectrometry
GB2427067B (en) * 2005-03-29 2010-02-24 Thermo Finnigan Llc Improvements relating to ion trapping
CA2629203C (fr) * 2006-01-05 2014-11-04 Mds Analytical Technologies, A Business Unit Of Mds Inc., Doing Business Through Its Sciex Division Acquisition dependante de l'information declenchee par defaut de masse
US7378653B2 (en) * 2006-01-10 2008-05-27 Varian, Inc. Increasing ion kinetic energy along axis of linear ion processing devices
GB0624679D0 (en) * 2006-12-11 2007-01-17 Shimadzu Corp A time-of-flight mass spectrometer and a method of analysing ions in a time-of-flight mass spectrometer
US8507850B2 (en) 2007-05-31 2013-08-13 Perkinelmer Health Sciences, Inc. Multipole ion guide interface for reduced background noise in mass spectrometry
JP2008108739A (ja) * 2007-11-26 2008-05-08 Hitachi High-Technologies Corp 質量分析装置およびこれを用いる計測システム
US7737396B2 (en) * 2008-01-30 2010-06-15 Mds Analytical Technologies, A Business Unit Of Mds Inc. Ion fragmentation in mass spectrometry
GB2484136B (en) * 2010-10-01 2015-09-16 Thermo Fisher Scient Bremen Method and apparatus for improving the throughput of a charged particle analysis system
WO2012068632A1 (fr) 2010-11-26 2012-05-31 Bruker Biosciences Pty Ltd Améliorations concernant ou liées à la spectrométrie de masse
JP2011119279A (ja) * 2011-03-11 2011-06-16 Hitachi High-Technologies Corp 質量分析装置およびこれを用いる計測システム
WO2013114196A1 (fr) * 2012-02-01 2013-08-08 Dh Technologies Development Pte. Ltd. Procédé et appareil pouvant améliorer la sensibilité d'un spectromètre de masse
EP3005401B1 (fr) * 2013-06-03 2022-04-06 PerkinElmer Health Sciences, Inc. Guide d'ions ou filtres présentant une conductance de gaz sélectionnée
GB201715777D0 (en) * 2017-09-29 2017-11-15 Shimadzu Corp ION Trap
KR102305532B1 (ko) * 2020-03-04 2021-09-27 한국원자력안전기술원 불활성 기체 정성 및 정량 분석 장치 및 방법
CN111640646A (zh) * 2020-06-15 2020-09-08 成都艾立本科技有限公司 一种高灵敏度质子转移飞行时间质谱仪及使用该质谱仪进行离子飞行时间测量的方法
CN111613514B (zh) * 2020-06-24 2023-11-03 成都艾立本科技有限公司 一种高灵敏度紫外光电离飞行时间质谱仪及离子飞行时间测量方法
WO2022239104A1 (fr) * 2021-05-11 2022-11-17 株式会社島津製作所 Spectromètre de masse à temps de vol à accélération orthogonale
US11501962B1 (en) * 2021-06-17 2022-11-15 Thermo Finnigan Llc Device geometries for controlling mass spectrometer pressures
GB202114780D0 (en) * 2021-10-15 2021-12-01 Thermo Fisher Scient Bremen Gmbh Ion transport between ion optical devices at different gas pressures

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328420A (en) 1980-07-28 1982-05-04 French John B Tandem mass spectrometer with open structure AC-only rod sections, and method of operating a mass spectrometer system
EP0237259A3 (fr) * 1986-03-07 1989-04-05 Finnigan Corporation Spectromètre de masse
US5179278A (en) * 1991-08-23 1993-01-12 Mds Health Group Limited Multipole inlet system for ion traps
US6011259A (en) * 1995-08-10 2000-01-04 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSN analysis
DE69535979D1 (de) 1994-02-28 2009-08-20 Analytica Of Branford Inc Multipol-ionenleiter für massenspektrometrie
DE19511333C1 (de) * 1995-03-28 1996-08-08 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer
WO1997002591A1 (fr) * 1995-07-03 1997-01-23 Hitachi, Ltd. Spectrometre de masse
EP0843887A1 (fr) * 1995-08-11 1998-05-27 Mds Health Group Limited Spectrometre a champ axial
CA2256028C (fr) * 1996-06-06 2007-01-16 Mds Inc. Spectrometre de masse multipolaire a ejection axiale
WO1999030350A1 (fr) * 1997-12-05 1999-06-17 University Of British Columbia Procede d'analyse d'ions dans un appareil comprenant un spectrometre de masse a temps de vol et un piege a ions lineaire
EP1057209B1 (fr) * 1998-01-23 2011-11-23 PerkinElmer Health Sciences, Inc. Spectrometrie de masse a guide d'ions multipolaire

Also Published As

Publication number Publication date
EP1090412A1 (fr) 2001-04-11
WO1999062101A1 (fr) 1999-12-02
JP2002517070A (ja) 2002-06-11
EP1090412A4 (fr) 2006-01-25
AU4326599A (en) 1999-12-13
WO1999062101A9 (fr) 2000-03-02
CA2332534C (fr) 2008-07-22
CA2332534A1 (fr) 1999-12-02
EP1090412B1 (fr) 2014-03-05
CA2626383C (fr) 2011-07-19

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Effective date: 20190529