CA2624897C - Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency - Google Patents

Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency Download PDF

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Publication number
CA2624897C
CA2624897C CA2624897A CA2624897A CA2624897C CA 2624897 C CA2624897 C CA 2624897C CA 2624897 A CA2624897 A CA 2624897A CA 2624897 A CA2624897 A CA 2624897A CA 2624897 C CA2624897 C CA 2624897C
Authority
CA
Canada
Prior art keywords
ergocalciferol
cholecalciferol
total
dosage form
hydroxyvitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2624897A
Other languages
English (en)
French (fr)
Other versions
CA2624897A1 (en
Inventor
Charles W. Bishop
Keith H. Crawford
Eric J. Messner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proventiv Therapeutics LLC
Original Assignee
Proventiv Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proventiv Therapeutics LLC filed Critical Proventiv Therapeutics LLC
Priority to CA2924200A priority Critical patent/CA2924200C/en
Publication of CA2624897A1 publication Critical patent/CA2624897A1/en
Application granted granted Critical
Publication of CA2624897C publication Critical patent/CA2624897C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2624897A 2005-10-12 2006-10-12 Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency Expired - Fee Related CA2624897C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2924200A CA2924200C (en) 2005-10-12 2006-10-12 Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72570905P 2005-10-12 2005-10-12
US60/725,709 2005-10-12
PCT/US2006/039787 WO2007047327A2 (en) 2005-10-12 2006-10-12 Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2924200A Division CA2924200C (en) 2005-10-12 2006-10-12 Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency

Publications (2)

Publication Number Publication Date
CA2624897A1 CA2624897A1 (en) 2007-04-26
CA2624897C true CA2624897C (en) 2017-02-14

Family

ID=37876888

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2624897A Expired - Fee Related CA2624897C (en) 2005-10-12 2006-10-12 Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency
CA2924200A Expired - Fee Related CA2924200C (en) 2005-10-12 2006-10-12 Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2924200A Expired - Fee Related CA2924200C (en) 2005-10-12 2006-10-12 Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency

Country Status (6)

Country Link
US (1) US20070122477A1 (https=)
EP (2) EP3047847A1 (https=)
JP (1) JP5303276B2 (https=)
CA (2) CA2624897C (https=)
ES (1) ES2567595T3 (https=)
WO (1) WO2007047327A2 (https=)

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SI3095447T1 (sl) 2006-02-03 2022-02-28 Opko Renal, Llc Zdravljenje pomanjkanja vitamina D s 25-hidroksivitaminom D2 in 25-hidroksivitaminom D3
HUE037309T2 (hu) 2006-06-21 2018-08-28 Opko Ireland Global Holdings Ltd Terápia D-vitamin telítési szer alkalmazásával és D-vitamin hormon helyettesítõ szer
DK2148684T3 (da) * 2007-04-25 2013-04-22 Cytochroma Inc Fremgangsmåde til behandling af vitamin D-insufficiens og -deficiens
PL2148661T3 (pl) 2007-04-25 2013-07-31 Cytochroma Inc Doustne kompozycje o kontrolowanym uwalnianiu zawierające związek będący witaminą D i woskowy nośnik
US8592401B2 (en) 2007-04-25 2013-11-26 Proventiv Therapeutics, Llc Methods and compounds for vitamin D therapy
PT3335712T (pt) 2007-04-25 2025-10-23 Opko Renal Llc Método de tratamento e prevenção seguro e eficaz do hiperparatiroidismo secundário na doença renal crónica
US20110124608A1 (en) * 2007-08-07 2011-05-26 Thau Kiong Chung Use of 25-hydroxy vitamin d3 to increase muscle mass in mammals
ES2599761T5 (en) * 2008-02-13 2025-06-18 Dsm Ip Assets Bv Use of 25-hydroxy-vitamin d3 and vitamin d to affect human muscle physiology
US20110039809A1 (en) * 2008-02-13 2011-02-17 Neil Robert Buck Combined use of 25-hydroxy-vitamin d3 and vitamin d3 for improving bone mineral density and for treating osteoporisis
CN106214683A (zh) * 2008-02-13 2016-12-14 帝斯曼知识产权资产管理有限公司 维生素d和25‑羟基维生素d3的组合
US20100331286A1 (en) * 2008-02-25 2010-12-30 Ray Chow Combination therapy for treatment of bone and mineral disorders for patients with impaired renal function
WO2009108297A2 (en) * 2008-02-25 2009-09-03 Nephrian, Inc. Combination therapy for treatment of bone and mineral disorders for patients with impaired renal function
CN102046812A (zh) * 2008-04-02 2011-05-04 赛特克罗公司 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒
LT2310059T (lt) * 2008-05-29 2017-03-27 Numat Biomedical S.L. Pufa dengti implantai
PT2552484T (pt) 2010-03-29 2020-04-03 Opko Ireland Global Holdings Ltd Métodos e composições para redução dos níveis de parafróides
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
CN104356038B (zh) * 2014-10-15 2016-06-01 中国科学院上海药物研究所 维生素d2与d3的共晶及其制备方法和用途
MY198547A (en) 2016-03-28 2023-09-04 Opko Ireland Global Holdings Ltd Methods of vitamin d treatment
CN117412739A (zh) * 2021-03-17 2024-01-16 索米克生物技术有限公司 维生素d制剂
EP4059490B1 (en) * 2021-03-17 2024-06-05 Solmic Biotech GmbH Process for manufacturing vitamin d formulations

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Also Published As

Publication number Publication date
EP1945185B1 (en) 2016-02-03
WO2007047327A2 (en) 2007-04-26
EP1945185A2 (en) 2008-07-23
ES2567595T3 (es) 2016-04-25
JP5303276B2 (ja) 2013-10-02
EP3047847A1 (en) 2016-07-27
CA2624897A1 (en) 2007-04-26
WO2007047327A3 (en) 2007-12-21
US20070122477A1 (en) 2007-05-31
JP2009511590A (ja) 2009-03-19
CA2924200A1 (en) 2007-04-26
CA2924200C (en) 2017-09-05

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Effective date: 20191015