CA2614750A1 - Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan - Google Patents

Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan Download PDF

Info

Publication number
CA2614750A1
CA2614750A1 CA002614750A CA2614750A CA2614750A1 CA 2614750 A1 CA2614750 A1 CA 2614750A1 CA 002614750 A CA002614750 A CA 002614750A CA 2614750 A CA2614750 A CA 2614750A CA 2614750 A1 CA2614750 A1 CA 2614750A1
Authority
CA
Canada
Prior art keywords
chitosan
hemostatic
agent
particle
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002614750A
Other languages
English (en)
French (fr)
Inventor
Simon J. Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HemCon Medical Technologies Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2614750A1 publication Critical patent/CA2614750A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0094—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00463—Plasters use haemostatic
    • A61F2013/00472—Plasters use haemostatic with chemical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00902—Plasters containing means
    • A61F2013/00927—Plasters containing means with biological activity, e.g. enzymes for debriding wounds or others, collagen or growth factors
    • A61F2013/00931—Plasters containing means with biological activity, e.g. enzymes for debriding wounds or others, collagen or growth factors chitin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA002614750A 2005-07-13 2006-07-13 Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan Abandoned CA2614750A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69873405P 2005-07-13 2005-07-13
US60/698,734 2005-07-13
PCT/US2006/027279 WO2007009050A2 (en) 2005-07-13 2006-07-13 Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan

Publications (1)

Publication Number Publication Date
CA2614750A1 true CA2614750A1 (en) 2007-01-18

Family

ID=37637971

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002614750A Abandoned CA2614750A1 (en) 2005-07-13 2006-07-13 Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan
CA002615058A Abandoned CA2615058A1 (en) 2005-07-13 2006-07-13 Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from chitosan and including a polymer mesh material of poly-4-hydroxy butyrate

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002615058A Abandoned CA2615058A1 (en) 2005-07-13 2006-07-13 Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from chitosan and including a polymer mesh material of poly-4-hydroxy butyrate

Country Status (9)

Country Link
US (1) US20070166387A1 (enExample)
EP (2) EP1906895A2 (enExample)
JP (2) JP2009505685A (enExample)
KR (2) KR20080044238A (enExample)
CN (2) CN101594887A (enExample)
AU (2) AU2006267047A1 (enExample)
CA (2) CA2614750A1 (enExample)
IL (2) IL188682A0 (enExample)
WO (2) WO2007009050A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8741335B2 (en) 2002-06-14 2014-06-03 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan
DK1401352T3 (da) 2001-06-14 2012-06-25 Kenton W Gregory Fremgangsmåde til fremstilling af en chitosansårforbinding
US9204957B2 (en) 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
JP5160102B2 (ja) * 2006-02-14 2013-03-13 甲陽ケミカル株式会社 非晶質の部分脱アセチル化キチン塩のスポンジ状止血材及びその製造方法
JP2009538192A (ja) 2006-05-23 2009-11-05 プロビデンス ヘルス システム−オレゴン ディー／ビー／エー プロビデンス セント ビンセント メディカル センター 体の内腔または体の中空器官内に包帯構造を導入および適用するシステムおよび方法
JP5581208B2 (ja) * 2007-07-18 2014-08-27 データレース リミテッド レーザー感受性被覆配合物
GB2461019B (en) 2008-04-25 2013-06-05 Medtrade Products Ltd Haemostatic material
AU2009241687A1 (en) 2008-05-02 2009-11-05 Providence Health System-Oregon D/B/A Providence St. Vincent Medical Center Wound dressing devices and methods
EP2340002B1 (en) 2008-10-06 2015-03-25 Providence Health System - Oregon Foam medical devices and methods
CN101862469B (zh) * 2010-05-28 2013-03-13 武汉人福医疗用品有限公司 一种壳聚糖衍生物快速止血颗粒及其制备方法
US9561300B2 (en) 2011-09-26 2017-02-07 Yes, Inc. Hemostatic compositions and dressings for bleeding
US8993831B2 (en) * 2011-11-01 2015-03-31 Arsenal Medical, Inc. Foam and delivery system for treatment of postpartum hemorrhage
GB2514592A (en) * 2013-05-30 2014-12-03 Medtrade Products Ltd Degradable haemostat composition
GB2514597A (en) * 2013-05-30 2014-12-03 Medtrade Products Ltd Degradable haemostat composition
CN104874029B (zh) * 2015-03-30 2018-04-27 陕西佰傲再生医学有限公司 一种止血防粘连材料及其制备方法
TR201713929A2 (tr) 2017-09-20 2019-04-22 Montero Gida Sanayi Ve Ticaret Anonim Sirketi Ki̇tosan ve alji̇natin hemostati̇k kompozi̇syonlari
CN111787892B (zh) * 2017-12-29 2025-02-18 金珂生物医疗公司 抵抗溶解的组织粘附脱乙酰壳多糖材料
US11660236B2 (en) 2017-12-29 2023-05-30 Tricol Biomedical, Inc. Delivery systems for control of bleeding in transurethral prostatectomy
US12636402B2 (en) 2017-12-29 2026-05-26 Tricol Biomedical, Inc. Chitosan dressing for control of gastrointestinal bleeding
US12156791B2 (en) 2017-12-29 2024-12-03 Tricol Biomedical, Inc. Chitosan dressing for control of bleeding in transurethral prostatectomy
KR102521769B1 (ko) * 2020-07-20 2023-04-14 주식회사 테라시온바이오메디칼 국소 지혈 파우더 조성물 및 이의 제조방법
CN114848668B (zh) * 2021-01-20 2024-03-26 香港中文大学 具有促进伤口愈合和快速止血功能的组合物
CN120919383B (zh) * 2025-10-13 2025-12-05 吉林大学 一种用于腹腔镜手术的医用海绵及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2923664A (en) * 1957-09-11 1960-02-02 Johnson & Johnson Hemostatic product
US4958011A (en) * 1983-06-27 1990-09-18 Bade Maria L Ester-stabilized chitin
JPS61240963A (ja) * 1985-04-18 1986-10-27 ユニチカ株式会社 創傷被覆保護材
US4952618A (en) * 1988-05-03 1990-08-28 Minnesota Mining And Manufacturing Company Hydrocolloid/adhesive composition
US4948540A (en) * 1988-08-01 1990-08-14 Semex Medical, Inc. Method of preparing collagen dressing sheet material
US5206028A (en) * 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
US5836970A (en) * 1996-08-02 1998-11-17 The Kendall Company Hemostatic wound dressing
JP3368323B2 (ja) * 1997-05-14 2003-01-20 独立行政法人農業生物資源研究所 キチンビーズ、キトサンビーズ、これらビーズの製造方法及びこれらビーズからなる担体並びに微胞子虫胞子の製造法
DE60036863T2 (de) * 1999-03-25 2008-07-31 Metabolix, Inc., Cambridge Medizinische vorrichtungen und verwendungen von polyhydroxyalkanoatpolymeren
DK1401352T3 (da) * 2001-06-14 2012-06-25 Kenton W Gregory Fremgangsmåde til fremstilling af en chitosansårforbinding
JP4955156B2 (ja) * 2001-06-25 2012-06-20 ユニチカ株式会社 止血材
US6992233B2 (en) * 2002-05-31 2006-01-31 Medafor, Inc. Material delivery system
US20050137512A1 (en) * 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
EP1638615B1 (en) * 2003-05-08 2014-10-29 Tepha, Inc. Polyhydroxyalkanoate medical textiles and fibers

Also Published As

Publication number Publication date
WO2007009090A3 (en) 2008-11-06
AU2006267047A1 (en) 2007-01-18
IL188683A0 (en) 2008-08-07
CA2615058A1 (en) 2007-01-18
CN101594887A (zh) 2009-12-02
US20070166387A1 (en) 2007-07-19
JP2009505685A (ja) 2009-02-12
WO2007009050A3 (en) 2009-06-11
EP1906896A4 (en) 2009-05-27
JP2009502749A (ja) 2009-01-29
KR20080030094A (ko) 2008-04-03
WO2007009090A2 (en) 2007-01-18
AU2006268143A8 (en) 2008-03-20
WO2007009050A2 (en) 2007-01-18
KR20080044238A (ko) 2008-05-20
EP1906895A2 (en) 2008-04-09
AU2006268143A1 (en) 2007-01-18
EP1906896A2 (en) 2008-04-09
IL188682A0 (en) 2008-08-07
CN101547686A (zh) 2009-09-30

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Legal Events

Date Code Title Description
FZDE Discontinued