KR20080044238A - 키토산으로부터 형성된 입상 지혈제를 사용하고폴리-4-히드록시 부티레이트의 중합체 망상 물질을포함하는 지혈 조성물, 집합체, 시스템 및 방법 - Google Patents

키토산으로부터 형성된 입상 지혈제를 사용하고폴리-4-히드록시 부티레이트의 중합체 망상 물질을포함하는 지혈 조성물, 집합체, 시스템 및 방법 Download PDF

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Publication number
KR20080044238A
KR20080044238A KR1020087003424A KR20087003424A KR20080044238A KR 20080044238 A KR20080044238 A KR 20080044238A KR 1020087003424 A KR1020087003424 A KR 1020087003424A KR 20087003424 A KR20087003424 A KR 20087003424A KR 20080044238 A KR20080044238 A KR 20080044238A
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KR
South Korea
Prior art keywords
chitosan
poly
particles
hemostatic
hydroxy butyrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020087003424A
Other languages
English (en)
Korean (ko)
Inventor
아자이 아후자
데이비드 마틴
사이먼 제이. 맥카티
Original Assignee
헴콘, 인크.
테파 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 헴콘, 인크., 테파 인크. filed Critical 헴콘, 인크.
Publication of KR20080044238A publication Critical patent/KR20080044238A/ko
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0094—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00463—Plasters use haemostatic
    • A61F2013/00472—Plasters use haemostatic with chemical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00902—Plasters containing means
    • A61F2013/00927—Plasters containing means with biological activity, e.g. enzymes for debriding wounds or others, collagen or growth factors
    • A61F2013/00931—Plasters containing means with biological activity, e.g. enzymes for debriding wounds or others, collagen or growth factors chitin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020087003424A 2005-07-13 2006-07-13 키토산으로부터 형성된 입상 지혈제를 사용하고폴리-4-히드록시 부티레이트의 중합체 망상 물질을포함하는 지혈 조성물, 집합체, 시스템 및 방법 Withdrawn KR20080044238A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69873405P 2005-07-13 2005-07-13
US60/698,734 2005-07-13

Publications (1)

Publication Number Publication Date
KR20080044238A true KR20080044238A (ko) 2008-05-20

Family

ID=37637971

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020087003424A Withdrawn KR20080044238A (ko) 2005-07-13 2006-07-13 키토산으로부터 형성된 입상 지혈제를 사용하고폴리-4-히드록시 부티레이트의 중합체 망상 물질을포함하는 지혈 조성물, 집합체, 시스템 및 방법
KR1020087003422A Withdrawn KR20080030094A (ko) 2005-07-13 2006-07-13 키토산과 같은 친수성 중합체 포움으로부터 형성된 입상지혈제를 사용하는 지혈 조성물, 집합체, 시스템 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020087003422A Withdrawn KR20080030094A (ko) 2005-07-13 2006-07-13 키토산과 같은 친수성 중합체 포움으로부터 형성된 입상지혈제를 사용하는 지혈 조성물, 집합체, 시스템 및 방법

Country Status (9)

Country Link
US (1) US20070166387A1 (enExample)
EP (2) EP1906896A4 (enExample)
JP (2) JP2009502749A (enExample)
KR (2) KR20080044238A (enExample)
CN (2) CN101547686A (enExample)
AU (2) AU2006267047A1 (enExample)
CA (2) CA2615058A1 (enExample)
IL (2) IL188682A0 (enExample)
WO (2) WO2007009050A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0210406A (pt) 2001-06-14 2006-04-04 Providence Health Sys Oregon curativo de ferimento, e, métodos de controle de sangramento severo, e de produção de um curativo de ferimento capaz de controlar o sangramento severo
US8741335B2 (en) 2002-06-14 2014-06-03 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan
US9204957B2 (en) 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
JP5160102B2 (ja) * 2006-02-14 2013-03-13 甲陽ケミカル株式会社 非晶質の部分脱アセチル化キチン塩のスポンジ状止血材及びその製造方法
EP2026850B1 (en) 2006-05-23 2014-07-09 Providence Health System-Oregon d/b/a Providence St. Vincent Medical Center Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ
CA2693892A1 (en) * 2007-07-18 2009-01-22 Jonathan Campbell Laser-sensitive coating formulation
GB2461019B (en) 2008-04-25 2013-06-05 Medtrade Products Ltd Haemostatic material
CA2723172A1 (en) 2008-05-02 2009-11-05 Providence Health System-Oregon D/B/A Providence St. Vincent Medical Cen Ter Wound dressing devices and methods
EP2340002B1 (en) * 2008-10-06 2015-03-25 Providence Health System - Oregon Foam medical devices and methods
CN101862469B (zh) * 2010-05-28 2013-03-13 武汉人福医疗用品有限公司 一种壳聚糖衍生物快速止血颗粒及其制备方法
WO2013048787A1 (en) 2011-09-26 2013-04-04 Yes, Inc. Novel hemostatic compositions and dressings for bleeding
US8993831B2 (en) * 2011-11-01 2015-03-31 Arsenal Medical, Inc. Foam and delivery system for treatment of postpartum hemorrhage
GB2514592A (en) * 2013-05-30 2014-12-03 Medtrade Products Ltd Degradable haemostat composition
GB2514597A (en) * 2013-05-30 2014-12-03 Medtrade Products Ltd Degradable haemostat composition
CN104874029B (zh) * 2015-03-30 2018-04-27 陕西佰傲再生医学有限公司 一种止血防粘连材料及其制备方法
TR201713929A2 (tr) 2017-09-20 2019-04-22 Montero Gida Sanayi Ve Ticaret Anonim Sirketi Ki̇tosan ve alji̇natin hemostati̇k kompozi̇syonlari
EP3731791B1 (en) * 2017-12-29 2024-02-07 Tricol Biomedical, Inc. Tissue adherent chitosan material that resists dissolution
US12156791B2 (en) 2017-12-29 2024-12-03 Tricol Biomedical, Inc. Chitosan dressing for control of bleeding in transurethral prostatectomy
KR102521769B1 (ko) * 2020-07-20 2023-04-14 주식회사 테라시온바이오메디칼 국소 지혈 파우더 조성물 및 이의 제조방법
CN114848668B (zh) * 2021-01-20 2024-03-26 香港中文大学 具有促进伤口愈合和快速止血功能的组合物
CN120919383B (zh) * 2025-10-13 2025-12-05 吉林大学 一种用于腹腔镜手术的医用海绵及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2923664A (en) * 1957-09-11 1960-02-02 Johnson & Johnson Hemostatic product
US4958011A (en) * 1983-06-27 1990-09-18 Bade Maria L Ester-stabilized chitin
JPS61240963A (ja) * 1985-04-18 1986-10-27 ユニチカ株式会社 創傷被覆保護材
US4952618A (en) * 1988-05-03 1990-08-28 Minnesota Mining And Manufacturing Company Hydrocolloid/adhesive composition
US4948540A (en) * 1988-08-01 1990-08-14 Semex Medical, Inc. Method of preparing collagen dressing sheet material
US5206028A (en) * 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
US5836970A (en) * 1996-08-02 1998-11-17 The Kendall Company Hemostatic wound dressing
US6156330A (en) * 1997-05-14 2000-12-05 Japan As Represented By Director General Of National Institute Of Sericultural And Entomological Sciences Ministry Of Agriculture, Forestry And Fisheries Chitin beads, chitosan beads, process for preparing these beads, carrier comprising said beads, and process for preparing microsporidian spore
DK1163019T3 (da) * 1999-03-25 2008-03-03 Metabolix Inc Medicinske indretninger og anvendelser af polyhydroxyalkanoatpolymere
BR0210406A (pt) * 2001-06-14 2006-04-04 Providence Health Sys Oregon curativo de ferimento, e, métodos de controle de sangramento severo, e de produção de um curativo de ferimento capaz de controlar o sangramento severo
JP4955156B2 (ja) * 2001-06-25 2012-06-20 ユニチカ株式会社 止血材
US6992233B2 (en) * 2002-05-31 2006-01-31 Medafor, Inc. Material delivery system
US20050137512A1 (en) * 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
EP2860292B1 (en) * 2003-05-08 2020-07-22 Tepha, Inc. Polyhydroxyalkanoate medical textiles and fibers

Also Published As

Publication number Publication date
JP2009505685A (ja) 2009-02-12
CA2615058A1 (en) 2007-01-18
IL188682A0 (en) 2008-08-07
CA2614750A1 (en) 2007-01-18
US20070166387A1 (en) 2007-07-19
WO2007009090A2 (en) 2007-01-18
CN101594887A (zh) 2009-12-02
WO2007009090A3 (en) 2008-11-06
CN101547686A (zh) 2009-09-30
WO2007009050A2 (en) 2007-01-18
EP1906896A4 (en) 2009-05-27
IL188683A0 (en) 2008-08-07
JP2009502749A (ja) 2009-01-29
EP1906896A2 (en) 2008-04-09
EP1906895A2 (en) 2008-04-09
AU2006268143A8 (en) 2008-03-20
WO2007009050A3 (en) 2009-06-11
KR20080030094A (ko) 2008-04-03
AU2006267047A1 (en) 2007-01-18
AU2006268143A1 (en) 2007-01-18

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20080212

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid