CA2613141A1 - Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders - Google Patents
Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders Download PDFInfo
- Publication number
- CA2613141A1 CA2613141A1 CA002613141A CA2613141A CA2613141A1 CA 2613141 A1 CA2613141 A1 CA 2613141A1 CA 002613141 A CA002613141 A CA 002613141A CA 2613141 A CA2613141 A CA 2613141A CA 2613141 A1 CA2613141 A1 CA 2613141A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- sirtuin
- formula
- activating compound
- further embodiment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pregnancy & Childbirth (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69744305P | 2005-07-07 | 2005-07-07 | |
| US60/697,443 | 2005-07-07 | ||
| US73652805P | 2005-11-14 | 2005-11-14 | |
| US60/736,528 | 2005-11-14 | ||
| US75360605P | 2005-12-23 | 2005-12-23 | |
| US60/753,606 | 2005-12-23 | ||
| US78380206P | 2006-03-16 | 2006-03-16 | |
| US60/783,802 | 2006-03-16 | ||
| PCT/US2006/026272 WO2007008548A2 (en) | 2005-07-07 | 2006-07-07 | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2613141A1 true CA2613141A1 (en) | 2007-01-18 |
Family
ID=37492426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002613141A Abandoned CA2613141A1 (en) | 2005-07-07 | 2006-07-07 | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1898897A2 (https=) |
| JP (1) | JP2009500357A (https=) |
| CN (1) | CN103055313A (https=) |
| AU (1) | AU2006269459B2 (https=) |
| CA (1) | CA2613141A1 (https=) |
| WO (1) | WO2007008548A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019143560A1 (en) * | 2018-01-16 | 2019-07-25 | The Regents Of The University Of California | Methods for promoting mitochondrial biogenesis in neural cells |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| AU2006218403A1 (en) | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | Fused heterocyclic compounds and their use as sirtuin modulators |
| ES2524922T3 (es) | 2005-05-10 | 2014-12-15 | Intermune, Inc. | Derivados de piridona para modular el sistema de proteína cinasa activada por estrés |
| WO2007049796A2 (en) * | 2005-10-26 | 2007-05-03 | Kao Corporation | Resveratrol and/or grape leaf extract as i. a. endurance improver, anti-aging agent, muscle strength improver |
| US7968711B2 (en) | 2006-04-24 | 2011-06-28 | Allergan, Inc. | Abnormal cannabidiols as agents for lowering intraocular pressure |
| US7718830B2 (en) | 2006-04-24 | 2010-05-18 | Allergan, Inc. | Abnormal cannabidiols as agents for lowering intraocular pressure |
| US7612101B2 (en) | 2006-04-24 | 2009-11-03 | Allergan, Inc. | Abnormal cannabidiols as agents for lowering intraocular pressure |
| US7618966B2 (en) | 2006-04-24 | 2009-11-17 | Allergan, Inc. | Abnormal Cannabidiols as agents for lowering intraocular pressure |
| US8778986B1 (en) * | 2007-01-25 | 2014-07-15 | University Of South Florida | Treatment of glycogen synthase kinase-based disease |
| US8802638B1 (en) * | 2007-01-25 | 2014-08-12 | University Of South Florida | Flavonoid treatment of glycogen synthase kinase-based disease |
| EP2124985A4 (en) * | 2007-01-26 | 2011-06-08 | Univ Washington | METHOD AND COMPOSITIONS FOR TREATING NERVOUS ELEMENTS |
| US20100130597A1 (en) | 2007-07-06 | 2010-05-27 | The United State Of America, As Represented By The Secretary Of The Dept Of Health And Human Service | Dna-pkcs modulates energy regulation and brain function |
| WO2009054994A2 (en) * | 2007-10-23 | 2009-04-30 | President And Fellows Of Harvard College | Sirt-3 related methods and compositions for mimicking exercise |
| EA021938B1 (ru) | 2008-05-01 | 2015-10-30 | Сертрис Фармасьютикалз, Инк. | Хинолины и их аналоги в качестве модуляторов сиртуина |
| CA2726588C (en) | 2008-06-03 | 2019-04-16 | Karl Kossen | Compounds and methods for treating inflammatory and fibrotic disorders |
| AU2009266889B2 (en) | 2008-07-03 | 2013-05-02 | Glaxosmithkline Llc | Benzimidazoles and related analogs as sirtuin modulators |
| WO2010020959A1 (en) * | 2008-08-21 | 2010-02-25 | University Of Cape Town | Resveratrol-containing composition for treating heart failure |
| US9326986B2 (en) | 2008-09-29 | 2016-05-03 | Glaxosmithkline Llc | Quinazolinone, quinolone and related analogs as sirtuin modulators |
| JP5655243B2 (ja) * | 2009-10-19 | 2015-01-21 | 国立大学法人 熊本大学 | インドキシル硫酸の産生の阻害剤のスクリーニング方法、インドキシル硫酸代謝産生阻害剤、及び腎障害軽減剤 |
| US9556201B2 (en) | 2009-10-29 | 2017-01-31 | Glaxosmithkline Llc | Bicyclic pyridines and analogs as sirtuin modulators |
| DK2496594T3 (en) * | 2009-11-06 | 2018-03-05 | The J David Gladstone Inst | METHODS AND COMPOSITIONS FOR MODULATING TAU LEVELS |
| JP5581071B2 (ja) * | 2010-02-03 | 2014-08-27 | 花王株式会社 | ミトコンドリア機能向上剤 |
| WO2012008549A1 (ja) * | 2010-07-15 | 2012-01-19 | 武田薬品工業株式会社 | 複素環化合物 |
| EP2610249B1 (en) * | 2010-08-26 | 2017-10-11 | Kyoto University | Pluripotent stem cell cardiomyocyte differentiation-promoting agent |
| US9499790B2 (en) | 2010-08-26 | 2016-11-22 | Kyoto University | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells |
| JP5850503B2 (ja) * | 2010-09-14 | 2016-02-03 | 北海道公立大学法人 札幌医科大学 | 筋ジストロフィーを処置するための組成物 |
| US9861116B2 (en) * | 2010-12-20 | 2018-01-09 | Hill's Pet Nutrition, Inc. | Pet food compositions for inducing a satiety response |
| AU2015201811B2 (en) * | 2010-12-20 | 2016-09-29 | Hill's Pet Nutrition, Inc. | Pet food compositions for inducing a satiety response |
| MX336980B (es) * | 2010-12-21 | 2016-02-09 | Senosiain S A De C V Lab | Combinacion y composicion para el tratamiento de obesidad. |
| WO2012114204A2 (en) | 2011-02-15 | 2012-08-30 | Ecole Polytechnique Federale De Lausanne (Epfl) Epfl-Tto | Methods of treating mitochondrial dysfunction |
| US9913880B2 (en) * | 2011-02-18 | 2018-03-13 | Stemdr Inc. | Method of treating sepsis or septic shock |
| EP2699236B1 (en) * | 2011-04-22 | 2018-06-20 | Napo Pharmaceuticals Inc | Pharmacologically optimized multimodal drug delivery system for nordihydroguiaretic acid (ndga) |
| EP3345901A3 (en) * | 2011-06-29 | 2018-09-12 | President and Fellows of Harvard College | Small molecules as antiaging agents |
| US8623924B2 (en) * | 2011-07-15 | 2014-01-07 | Nusirt Sciences, Inc. | Compositions and methods for modulating metabolic pathways |
| JP6155191B2 (ja) * | 2011-10-02 | 2017-06-28 | キユーピー株式会社 | RNA干渉によるmRNA発現の抑制を促進する促進剤およびその用途 |
| WO2013074948A1 (en) | 2011-11-16 | 2013-05-23 | Resveratrol Partners, Llc | Compositions containing resveratrol and nucleotides |
| KR101996343B1 (ko) | 2012-01-27 | 2019-07-05 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 전능성 줄기세포의 심근분화 유도방법 |
| EP2872128B1 (en) | 2012-07-16 | 2020-02-19 | Cornell University | Nicotinamide riboside to treat hearing loss |
| WO2014014816A2 (en) * | 2012-07-17 | 2014-01-23 | Ngm Biopharmaceuticals, Inc. | Methods of treating glucose metabolism disorders |
| WO2014014819A2 (en) * | 2012-07-17 | 2014-01-23 | Ngm Biopharmaceuticals, Inc. | Methods of treating glucose metabolism disorders |
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| MX2015006023A (es) | 2012-11-13 | 2016-03-31 | Nusirt Sciences Inc | Composiciones y metodos para incrementar el metabolismo energetico. |
| WO2014136519A1 (ja) | 2013-03-08 | 2014-09-12 | 国立大学法人京都大学 | Egf受容体阻害剤を含む多能性幹細胞の心筋分化促進剤 |
| CN105228627B (zh) * | 2013-03-15 | 2018-07-13 | 纽斯尔特科学公司 | 亮氨酸和烟酸降低脂质水平 |
| WO2014199171A1 (en) * | 2013-06-12 | 2014-12-18 | Proximagen Limited | New therapeutic uses of enzyme inhibitors |
| US20160101072A1 (en) * | 2013-06-12 | 2016-04-14 | Proximagen Limited | Therapeutic uses of enzyme inhibitors |
| KR20220098049A (ko) * | 2013-10-30 | 2022-07-08 | 크로마덱스 아이엔씨. | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
| MX382781B (es) | 2014-04-02 | 2025-03-13 | Intermune Inc | Piridinonas anti-fibroticas. |
| EP3150705B1 (en) | 2014-05-30 | 2019-05-15 | Kyoto University | Method for inducing myocardial differentiation of pluripotent stem cells using low-molecular compound |
| US9370503B1 (en) * | 2015-02-26 | 2016-06-21 | Chi Chou Liao | Compounds for treating ocular diseases |
| WO2016158212A1 (ja) * | 2015-03-31 | 2016-10-06 | 新興和製薬株式会社 | レスベラトロールとニコチンアミドモノヌクレオチドを含む食品組成物 |
| WO2017042198A2 (en) * | 2015-09-08 | 2017-03-16 | Ecole Polytechnique Federale De Lausanne (Epfl) | Agents and methods using thereof for the prevention and treatment of stem cell muscle disorders |
| AU2016375177B2 (en) * | 2015-12-24 | 2022-09-01 | Amazentis Sa | Compositions comprising nicotinamide riboside and a urolithin |
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| JP2018172346A (ja) * | 2017-03-31 | 2018-11-08 | 株式会社東洋新薬 | 妊娠サポート用組成物 |
| EP3388072A1 (en) * | 2017-04-10 | 2018-10-17 | Universität Leipzig | Ubiquinone-independent cytoplasmic dihydroorotate dehydrogenase for use as medicament |
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| US6878751B1 (en) * | 2000-10-19 | 2005-04-12 | Imperial College Of Science Technology And Medicine | Administration of resveratrol to treat inflammatory respiratory disorders |
| WO2002081651A2 (en) * | 2001-02-20 | 2002-10-17 | Uab Research Foundation | Polyphenolics for enhancing endothelial cell-mediated fibrinolysis |
| MXPA04000834A (es) * | 2002-05-27 | 2005-08-26 | Advance Holdings Ltd | Suplementos dieteticos de vinasa de vino y un proceso importante de produccion. |
| EP2218342B1 (en) * | 2003-05-27 | 2018-07-04 | DSM IP Assets B.V. | Novel nutraceutical compositions and use thereof |
| CA2529510A1 (en) * | 2003-07-01 | 2005-01-13 | President And Fellows Of Harvard College | Compositions for manipulating the lifespan and stress response of cells and organisms |
| EP1708689A2 (en) * | 2003-12-29 | 2006-10-11 | The President and Fellows of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
| US7714161B2 (en) * | 2004-01-20 | 2010-05-11 | Brigham Young University | Sirtuin activating compounds and methods for making the same |
| CN1956733B (zh) * | 2004-04-07 | 2012-10-10 | 白藜芦醇合伙人有限责任公司 | 营养补充剂及其加工方法 |
| JP2008527002A (ja) * | 2005-01-13 | 2008-07-24 | サートリス ファーマシューティカルズ, インコーポレイテッド | 神経変性障害および血液凝固障害を予防および処置するための新規組成物 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019143560A1 (en) * | 2018-01-16 | 2019-07-25 | The Regents Of The University Of California | Methods for promoting mitochondrial biogenesis in neural cells |
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| EP1898897A2 (en) | 2008-03-19 |
| JP2009500357A (ja) | 2009-01-08 |
| AU2006269459B2 (en) | 2013-02-07 |
| AU2006269459A1 (en) | 2007-01-18 |
| WO2007008548A3 (en) | 2007-08-09 |
| WO2007008548A2 (en) | 2007-01-18 |
| CN103055313A (zh) | 2013-04-24 |
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