CA2601243A1 - Methodes et composition relatives a l'imagerie in vivo d'une expression genique - Google Patents
Methodes et composition relatives a l'imagerie in vivo d'une expression genique Download PDFInfo
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- CA2601243A1 CA2601243A1 CA002601243A CA2601243A CA2601243A1 CA 2601243 A1 CA2601243 A1 CA 2601243A1 CA 002601243 A CA002601243 A CA 002601243A CA 2601243 A CA2601243 A CA 2601243A CA 2601243 A1 CA2601243 A1 CA 2601243A1
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
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- Epidemiology (AREA)
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- Medicinal Chemistry (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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US65984405P | 2005-03-09 | 2005-03-09 | |
US60/659,844 | 2005-03-09 | ||
PCT/US2006/008374 WO2006099019A2 (fr) | 2005-03-09 | 2006-03-09 | Methodes et composition relatives a l'imagerie in vivo d'une expression genique |
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CA2601243A1 true CA2601243A1 (fr) | 2006-09-21 |
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CA002601243A Abandoned CA2601243A1 (fr) | 2005-03-09 | 2006-03-09 | Methodes et composition relatives a l'imagerie in vivo d'une expression genique |
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EP (1) | EP1866421A2 (fr) |
JP (1) | JP2008532519A (fr) |
KR (1) | KR20070119664A (fr) |
CN (1) | CN101171337A (fr) |
AU (1) | AU2006223435A1 (fr) |
CA (1) | CA2601243A1 (fr) |
RU (1) | RU2007137263A (fr) |
WO (1) | WO2006099019A2 (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2128259A1 (fr) | 2008-05-27 | 2009-12-02 | Koninklijke Philips Electronics N.V. | Administration de thérapie et surveillance utilisant un gène de protéine de fusion de rapporteur-intérêt et imagerie optique |
WO2011135040A1 (fr) | 2010-04-30 | 2011-11-03 | F. Hoffmann-La Roche Ag | Protéine de fusion d'anticorps fluorescent, sa production et son utilisation |
CA2810838C (fr) | 2010-09-08 | 2021-07-06 | The Board Of Regents Of The University Of Texas System | Therapie anticancereuse sur la base des recepteurs de la somatostatine |
CN101985464B (zh) * | 2010-10-22 | 2013-01-16 | 暨南大学 | 高稳定性pac1型受体特异激动剂mpapo及其制备方法与应用 |
US20120288442A1 (en) * | 2011-05-11 | 2012-11-15 | Atomic Energy Council-Institute Of Nuclear Energy Research | Nuclear Imaging Method Using Molecular Target Detection Agent for Liver Fibrosis |
CN102393458B (zh) * | 2011-08-24 | 2013-12-18 | 绍兴市人民医院 | 一种早期乳腺癌血清诊断试剂 |
CN102393457A (zh) * | 2011-08-24 | 2012-03-28 | 绍兴市人民医院 | 早期乳腺癌血清诊断试剂及其检测方法 |
CN102533857B (zh) * | 2012-02-21 | 2014-05-07 | 西北农林科技大学 | 一种hbd3气管上皮特异性表达载体及其构建的重组细胞 |
CN107076724B (zh) * | 2013-03-29 | 2020-03-03 | 国立大学法人三重大学 | 生物体染色剂 |
EP2801622A1 (fr) * | 2013-05-08 | 2014-11-12 | DeltaCell B.V. | Système rapporteur à marqueurs multiples |
EP3674408A1 (fr) * | 2014-06-16 | 2020-07-01 | The Johns Hopkins University | Compositions et procédés pour l'expression d'arn guide de crispr à l'aide du promoteur h1 |
JP6793451B2 (ja) * | 2014-11-14 | 2020-12-02 | キヤノンメディカルシステムズ株式会社 | 被検細胞の細胞特性を評価するための遺伝子マーカー、方法、レポーターベクター、プライマーセットおよびアッセイキット、並びに細胞特性評価装置 |
CN104877966A (zh) * | 2014-12-23 | 2015-09-02 | 昆明理工大学 | 一种p2y1/u2os细胞株及其制备方法及应用 |
AU2017229495C1 (en) * | 2016-03-07 | 2020-05-14 | Quidel Cardiovascular Inc. | Immunoassay controls and the use thereof |
TWI826351B (zh) * | 2016-05-31 | 2023-12-21 | 大陸商鴻運華寧(杭州)生物醫藥有限公司 | R抗體,其藥物組合物及其應用 |
JOP20190187A1 (ar) | 2017-02-03 | 2019-08-01 | Novartis Ag | مترافقات عقار جسم مضاد لـ ccr7 |
CN113501881B (zh) * | 2017-09-27 | 2023-07-28 | 北京大学 | 融合蛋白 |
CN108535950B (zh) * | 2018-02-27 | 2019-10-29 | 浙江省海洋水产研究所 | 一种硬骨鱼类骨骼生长模型用成像方法 |
CN109504709B (zh) * | 2018-11-28 | 2020-07-24 | 上海安民生物技术有限公司 | 白蛋白启动子驱动的白蛋白表达载体 |
CA3130525A1 (fr) * | 2019-04-08 | 2020-10-15 | Giuseppe RONZITTI | Promoteurs hybrides pour l'expression musculaire |
RU2735281C1 (ru) * | 2019-11-25 | 2020-10-29 | федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (национальный исследовательский университет)" | Модифицированная генетическая конструкция для рекомбинантной экспрессии и кристаллизации человеческого CysLT1 рецептора |
CN113444802B (zh) * | 2021-07-01 | 2024-02-06 | 复旦大学附属肿瘤医院 | Htr1a在乳腺癌诊断、治疗和预后中的应用 |
CN114751990B (zh) * | 2022-04-01 | 2023-10-20 | 中国科学技术大学 | 酰胺高丝氨酸内酯受体-增强绿色荧光融合蛋白及其制备方法与应用 |
WO2024116101A1 (fr) * | 2022-11-29 | 2024-06-06 | Neuracle Science Co., Ltd. | Utilisation d'agonistes de galr2 pour traiter des troubles gastro-intestinaux et/ou endocriniens |
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US6093545A (en) * | 1997-12-04 | 2000-07-25 | Millennium Pharmaceuticals, Inc. | Methods for detecting nucleic acid molecules encoding a member of the muscarinic family of receptors |
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- 2006-03-09 EP EP06748324A patent/EP1866421A2/fr not_active Withdrawn
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- 2006-03-09 WO PCT/US2006/008374 patent/WO2006099019A2/fr active Application Filing
- 2006-03-09 CA CA002601243A patent/CA2601243A1/fr not_active Abandoned
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WO2006099019A2 (fr) | 2006-09-21 |
EP1866421A2 (fr) | 2007-12-19 |
AU2006223435A1 (en) | 2006-09-21 |
WO2006099019A3 (fr) | 2007-04-05 |
RU2007137263A (ru) | 2009-04-20 |
CN101171337A (zh) | 2008-04-30 |
WO2006099019A8 (fr) | 2008-01-24 |
KR20070119664A (ko) | 2007-12-20 |
JP2008532519A (ja) | 2008-08-21 |
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