CA2601243A1 - Methodes et composition relatives a l'imagerie in vivo d'une expression genique - Google Patents

Methodes et composition relatives a l'imagerie in vivo d'une expression genique Download PDF

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Publication number
CA2601243A1
CA2601243A1 CA002601243A CA2601243A CA2601243A1 CA 2601243 A1 CA2601243 A1 CA 2601243A1 CA 002601243 A CA002601243 A CA 002601243A CA 2601243 A CA2601243 A CA 2601243A CA 2601243 A1 CA2601243 A1 CA 2601243A1
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CA
Canada
Prior art keywords
promoter sequence
promoter
nucleic acid
sequence
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002601243A
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English (en)
Inventor
Vikas Kundra
Bingliang Fang
Lin X. Ji
Dan Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2601243A1 publication Critical patent/CA2601243A1/fr
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/15Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/60Vector systems having a special element relevant for transcription from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002601243A 2005-03-09 2006-03-09 Methodes et composition relatives a l'imagerie in vivo d'une expression genique Abandoned CA2601243A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65984405P 2005-03-09 2005-03-09
US60/659,844 2005-03-09
PCT/US2006/008374 WO2006099019A2 (fr) 2005-03-09 2006-03-09 Methodes et composition relatives a l'imagerie in vivo d'une expression genique

Publications (1)

Publication Number Publication Date
CA2601243A1 true CA2601243A1 (fr) 2006-09-21

Family

ID=36794233

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002601243A Abandoned CA2601243A1 (fr) 2005-03-09 2006-03-09 Methodes et composition relatives a l'imagerie in vivo d'une expression genique

Country Status (8)

Country Link
EP (1) EP1866421A2 (fr)
JP (1) JP2008532519A (fr)
KR (1) KR20070119664A (fr)
CN (1) CN101171337A (fr)
AU (1) AU2006223435A1 (fr)
CA (1) CA2601243A1 (fr)
RU (1) RU2007137263A (fr)
WO (1) WO2006099019A2 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2128259A1 (fr) 2008-05-27 2009-12-02 Koninklijke Philips Electronics N.V. Administration de thérapie et surveillance utilisant un gène de protéine de fusion de rapporteur-intérêt et imagerie optique
WO2011135040A1 (fr) 2010-04-30 2011-11-03 F. Hoffmann-La Roche Ag Protéine de fusion d'anticorps fluorescent, sa production et son utilisation
CA2810838C (fr) 2010-09-08 2021-07-06 The Board Of Regents Of The University Of Texas System Therapie anticancereuse sur la base des recepteurs de la somatostatine
CN101985464B (zh) * 2010-10-22 2013-01-16 暨南大学 高稳定性pac1型受体特异激动剂mpapo及其制备方法与应用
US20120288442A1 (en) * 2011-05-11 2012-11-15 Atomic Energy Council-Institute Of Nuclear Energy Research Nuclear Imaging Method Using Molecular Target Detection Agent for Liver Fibrosis
CN102393458B (zh) * 2011-08-24 2013-12-18 绍兴市人民医院 一种早期乳腺癌血清诊断试剂
CN102393457A (zh) * 2011-08-24 2012-03-28 绍兴市人民医院 早期乳腺癌血清诊断试剂及其检测方法
CN102533857B (zh) * 2012-02-21 2014-05-07 西北农林科技大学 一种hbd3气管上皮特异性表达载体及其构建的重组细胞
CN107076724B (zh) * 2013-03-29 2020-03-03 国立大学法人三重大学 生物体染色剂
EP2801622A1 (fr) * 2013-05-08 2014-11-12 DeltaCell B.V. Système rapporteur à marqueurs multiples
EP3674408A1 (fr) * 2014-06-16 2020-07-01 The Johns Hopkins University Compositions et procédés pour l'expression d'arn guide de crispr à l'aide du promoteur h1
JP6793451B2 (ja) * 2014-11-14 2020-12-02 キヤノンメディカルシステムズ株式会社 被検細胞の細胞特性を評価するための遺伝子マーカー、方法、レポーターベクター、プライマーセットおよびアッセイキット、並びに細胞特性評価装置
CN104877966A (zh) * 2014-12-23 2015-09-02 昆明理工大学 一种p2y1/u2os细胞株及其制备方法及应用
AU2017229495C1 (en) * 2016-03-07 2020-05-14 Quidel Cardiovascular Inc. Immunoassay controls and the use thereof
TWI826351B (zh) * 2016-05-31 2023-12-21 大陸商鴻運華寧(杭州)生物醫藥有限公司 R抗體,其藥物組合物及其應用
JOP20190187A1 (ar) 2017-02-03 2019-08-01 Novartis Ag مترافقات عقار جسم مضاد لـ ccr7
CN113501881B (zh) * 2017-09-27 2023-07-28 北京大学 融合蛋白
CN108535950B (zh) * 2018-02-27 2019-10-29 浙江省海洋水产研究所 一种硬骨鱼类骨骼生长模型用成像方法
CN109504709B (zh) * 2018-11-28 2020-07-24 上海安民生物技术有限公司 白蛋白启动子驱动的白蛋白表达载体
CA3130525A1 (fr) * 2019-04-08 2020-10-15 Giuseppe RONZITTI Promoteurs hybrides pour l'expression musculaire
RU2735281C1 (ru) * 2019-11-25 2020-10-29 федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (национальный исследовательский университет)" Модифицированная генетическая конструкция для рекомбинантной экспрессии и кристаллизации человеческого CysLT1 рецептора
CN113444802B (zh) * 2021-07-01 2024-02-06 复旦大学附属肿瘤医院 Htr1a在乳腺癌诊断、治疗和预后中的应用
CN114751990B (zh) * 2022-04-01 2023-10-20 中国科学技术大学 酰胺高丝氨酸内酯受体-增强绿色荧光融合蛋白及其制备方法与应用
WO2024116101A1 (fr) * 2022-11-29 2024-06-06 Neuracle Science Co., Ltd. Utilisation d'agonistes de galr2 pour traiter des troubles gastro-intestinaux et/ou endocriniens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093545A (en) * 1997-12-04 2000-07-25 Millennium Pharmaceuticals, Inc. Methods for detecting nucleic acid molecules encoding a member of the muscarinic family of receptors

Also Published As

Publication number Publication date
WO2006099019A2 (fr) 2006-09-21
EP1866421A2 (fr) 2007-12-19
AU2006223435A1 (en) 2006-09-21
WO2006099019A3 (fr) 2007-04-05
RU2007137263A (ru) 2009-04-20
CN101171337A (zh) 2008-04-30
WO2006099019A8 (fr) 2008-01-24
KR20070119664A (ko) 2007-12-20
JP2008532519A (ja) 2008-08-21

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FZDE Discontinued