CA2600525A1 - Biomarkers for efficacy of aliskiren as a hypertensive agent - Google Patents
Biomarkers for efficacy of aliskiren as a hypertensive agent Download PDFInfo
- Publication number
- CA2600525A1 CA2600525A1 CA002600525A CA2600525A CA2600525A1 CA 2600525 A1 CA2600525 A1 CA 2600525A1 CA 002600525 A CA002600525 A CA 002600525A CA 2600525 A CA2600525 A CA 2600525A CA 2600525 A1 CA2600525 A1 CA 2600525A1
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- Prior art keywords
- gene
- individual
- aliskiren
- snp
- angiotensin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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| US74240106P | 2006-02-06 | 2006-02-06 | |
| US60/742,401 | 2006-02-06 | ||
| PCT/US2006/009913 WO2006102177A2 (en) | 2005-03-22 | 2006-03-20 | Biomarkers for efficacy of aliskiren as a hypertensive agent |
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| PT2205279E (pt) * | 2007-09-28 | 2011-07-11 | Novartis Ag | Associação farmacêutica de aliscireno e valsartan |
| CN108660205A (zh) * | 2018-07-04 | 2018-10-16 | 刘城 | 一种糖尿病遗传风险评估试剂盒及其运用 |
| CN111024960B (zh) * | 2019-12-27 | 2023-02-17 | 广州阳普医疗科技股份有限公司 | 用于高血压血样检测的添加剂、试剂盒和应用 |
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| WO1988008457A1 (en) * | 1987-04-30 | 1988-11-03 | Biotechnology Research Partners, Ltd. | Hypertension-related blood tests useful as genetic markers |
| WO2000022166A2 (en) * | 1998-10-14 | 2000-04-20 | Pyrosequencing Ab | Genes for assessing cardiovascular status and compositions for use thereof |
| PL219032B1 (pl) * | 2002-05-17 | 2015-03-31 | Novartis Ag | Kompozycja farmaceutyczna zawierająca alskiren, amlodypinę i hydrochlortiazyd, kombinacja zawierająca te składniki, zastosowanie wspomnianej kombinacji oraz zestaw handlowy zawierający wspomnianą kombinację |
| US8304190B2 (en) * | 2005-02-02 | 2012-11-06 | Royal College Of Surgeons In Ireland | Pharmacogenomics of blood pressure lowering agents |
| BRPI0609702A2 (pt) * | 2005-03-22 | 2010-04-20 | Novartis Ag | biomarcadores para a eficácia de aliskiren como um agente hipertensivo |
-
2006
- 2006-03-20 BR BRPI0609702-2A patent/BRPI0609702A2/pt not_active IP Right Cessation
- 2006-03-20 JP JP2008503059A patent/JP2008538549A/ja active Pending
- 2006-03-20 CA CA002600525A patent/CA2600525A1/en not_active Abandoned
- 2006-03-20 US US11/909,202 patent/US20100240760A1/en not_active Abandoned
- 2006-03-20 AU AU2006227283A patent/AU2006227283B2/en not_active Ceased
- 2006-03-20 WO PCT/US2006/009913 patent/WO2006102177A2/en not_active Ceased
- 2006-03-20 KR KR1020077024124A patent/KR20080005926A/ko not_active Ceased
- 2006-03-20 MX MX2007011697A patent/MX2007011697A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0609702A2 (pt) | 2010-04-20 |
| AU2006227283B2 (en) | 2010-07-01 |
| WO2006102177A2 (en) | 2006-09-28 |
| US20100240760A1 (en) | 2010-09-23 |
| JP2008538549A (ja) | 2008-10-30 |
| MX2007011697A (es) | 2007-11-16 |
| WO2006102177A3 (en) | 2007-05-10 |
| KR20080005926A (ko) | 2008-01-15 |
| AU2006227283A1 (en) | 2006-09-28 |
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