CA2600132C - Stabilizing enzyme activity in electrochemical biosensors - Google Patents

Stabilizing enzyme activity in electrochemical biosensors Download PDF

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Publication number
CA2600132C
CA2600132C CA2600132A CA2600132A CA2600132C CA 2600132 C CA2600132 C CA 2600132C CA 2600132 A CA2600132 A CA 2600132A CA 2600132 A CA2600132 A CA 2600132A CA 2600132 C CA2600132 C CA 2600132C
Authority
CA
Canada
Prior art keywords
composition
reagent composition
electrochemical biosensor
total weight
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2600132A
Other languages
English (en)
French (fr)
Other versions
CA2600132A1 (en
Inventor
Amy H. Chu
Hope G. Spradlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ascensia Diabetes Care Holdings AG
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Publication of CA2600132A1 publication Critical patent/CA2600132A1/en
Application granted granted Critical
Publication of CA2600132C publication Critical patent/CA2600132C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CA2600132A 2005-03-04 2006-03-03 Stabilizing enzyme activity in electrochemical biosensors Expired - Fee Related CA2600132C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65863405P 2005-03-04 2005-03-04
US60/658,634 2005-03-04
PCT/US2006/007875 WO2006096619A2 (en) 2005-03-04 2006-03-03 Stabilizing the activity of pqq-dependent glucose dehydrogenase in electrochemical biosensors

Publications (2)

Publication Number Publication Date
CA2600132A1 CA2600132A1 (en) 2006-09-14
CA2600132C true CA2600132C (en) 2014-09-09

Family

ID=36677188

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2600132A Expired - Fee Related CA2600132C (en) 2005-03-04 2006-03-03 Stabilizing enzyme activity in electrochemical biosensors

Country Status (14)

Country Link
US (3) US8921065B2 (enExample)
EP (1) EP1859048B1 (enExample)
JP (2) JP5020832B2 (enExample)
KR (1) KR20070114802A (enExample)
CN (1) CN101133162A (enExample)
AU (1) AU2006220770A1 (enExample)
BR (1) BRPI0607841A2 (enExample)
CA (1) CA2600132C (enExample)
MX (1) MX2007010778A (enExample)
NO (1) NO20074925L (enExample)
RU (1) RU2422534C2 (enExample)
TW (1) TW200643173A (enExample)
WO (1) WO2006096619A2 (enExample)
ZA (1) ZA200708312B (enExample)

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CA2807519C (en) * 2005-11-14 2016-01-12 Bayer Healthcare Llc Test sensor reagent having cellulose polymers
CN101517093B (zh) 2006-09-22 2016-01-06 拜尔健康护理有限责任公司 具有增强的稳定性和血细胞比容性能的生物传感器系统
JP5856371B2 (ja) 2007-12-10 2016-02-09 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ 分析対象物を検出するための試薬及び方法
WO2009076412A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Method of depositing reagent material in a test sensor
US7678250B2 (en) * 2008-01-22 2010-03-16 Home Diagnostics, Inc. Reagent compositions for use in electrochemical detection
EP2318837B1 (en) 2008-07-11 2016-01-13 Universal Biosensors, Pty. Ltd. Enhanced immunoassay sensor
US20100270152A1 (en) * 2009-04-24 2010-10-28 Lifescan Scotland Limited Enzymatic reagent ink
US8025788B2 (en) * 2009-04-24 2011-09-27 Lifescan Scotland Limited Method for manufacturing an enzymatic reagent ink
US20100273249A1 (en) * 2009-04-24 2010-10-28 Lifescan Scotland Limited Analytical test strips
US8409412B2 (en) * 2010-08-23 2013-04-02 Lifescan Scotland, Ltd. Enzymatic reagent inks for use in test strips having a predetermined calibration code
BR112014000257A2 (pt) * 2011-07-06 2017-03-01 Advanced Liquid Logic Inc armazenamento de reagente em um atuador de gota
KR101239381B1 (ko) 2012-05-02 2013-03-05 주식회사 아이센스 산화환원반응용 시약의 안정제 조성물
US9097659B2 (en) * 2013-03-14 2015-08-04 Bayer Healthcare Llc Maintaining electrode function during manufacture with a protective layer
KR20180023912A (ko) * 2015-06-01 2018-03-07 더 유니버서티 어브 퀸슬랜드 전기화학적 바이오센서
CN108802157A (zh) * 2018-06-22 2018-11-13 桂林中辉科技发展有限公司 一种总胆汁酸检测试剂、试纸及检测方法与应用
WO2020242967A1 (en) * 2019-05-28 2020-12-03 W. L. Gore & Associates, Inc. Stabilized medical device and method for making it
CN114923965B (zh) * 2022-03-18 2023-05-23 杭州微策生物技术股份有限公司 一种一体式多指标传感器及其制作方法

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US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
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US5429735A (en) 1994-06-27 1995-07-04 Miles Inc. Method of making and amperometric electrodes
JP3775518B2 (ja) * 1995-11-22 2006-05-17 東洋紡績株式会社 Ｐｑｑ依存性グルコースデヒドロゲナーゼ組成物およびグルコース測定用試薬組成物
US5708247A (en) 1996-02-14 1998-01-13 Selfcare, Inc. Disposable glucose test strips, and methods and compositions for making same
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JP3370504B2 (ja) 1996-03-13 2003-01-27 松下電器産業株式会社 バイオセンサ
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DE19849000A1 (de) * 1998-10-23 2000-04-27 Roche Diagnostics Gmbh Funktionsschichten mit hoher Präzision, Verfahren zu ihrer Herstellung und Teststreifen enthaltend diese Funktionsschichten
CA2305922C (en) 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
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Also Published As

Publication number Publication date
KR20070114802A (ko) 2007-12-04
WO2006096619A2 (en) 2006-09-14
US20190249214A1 (en) 2019-08-15
JP2012198218A (ja) 2012-10-18
WO2006096619A3 (en) 2006-11-23
TW200643173A (en) 2006-12-16
RU2422534C2 (ru) 2011-06-27
NO20074925L (no) 2007-11-02
JP5020832B2 (ja) 2012-09-05
RU2007136760A (ru) 2009-04-10
AU2006220770A1 (en) 2006-09-14
BRPI0607841A2 (pt) 2009-06-13
JP5236824B2 (ja) 2013-07-17
US20150076003A1 (en) 2015-03-19
EP1859048B1 (en) 2014-06-18
ZA200708312B (en) 2008-11-26
JP2008532047A (ja) 2008-08-14
MX2007010778A (es) 2007-11-07
CN101133162A (zh) 2008-02-27
US8921065B2 (en) 2014-12-30
EP1859048A2 (en) 2007-11-28
US20080199937A1 (en) 2008-08-21
CA2600132A1 (en) 2006-09-14

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