CA2594187C - Method for producing probiotically derived compounds - Google Patents

Method for producing probiotically derived compounds Download PDF

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Publication number
CA2594187C
CA2594187C CA2594187A CA2594187A CA2594187C CA 2594187 C CA2594187 C CA 2594187C CA 2594187 A CA2594187 A CA 2594187A CA 2594187 A CA2594187 A CA 2594187A CA 2594187 C CA2594187 C CA 2594187C
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CA
Canada
Prior art keywords
microbiological culture
compounds
derived
broth
probiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2594187A
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English (en)
French (fr)
Other versions
CA2594187A1 (en
Inventor
Robert J. Marshall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Premier Research Labs LP
Original Assignee
Premier Research Labs LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Premier Research Labs LP filed Critical Premier Research Labs LP
Priority to CA2830842A priority Critical patent/CA2830842A1/en
Publication of CA2594187A1 publication Critical patent/CA2594187A1/en
Application granted granted Critical
Publication of CA2594187C publication Critical patent/CA2594187C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/167—Heterorings having sulfur atoms as ring heteroatoms, e.g. vitamin B1, thiamine nucleus and open chain analogs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
CA2594187A 2005-01-03 2005-12-30 Method for producing probiotically derived compounds Expired - Fee Related CA2594187C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2830842A CA2830842A1 (en) 2005-01-03 2005-12-30 Method for producing probiotically derived compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/028,272 2005-01-03
US11/028,272 US8530209B2 (en) 2003-11-26 2005-01-03 Method for producing probiotically derived compounds
PCT/US2005/047497 WO2006074094A2 (en) 2005-01-03 2005-12-30 Method for producing probiotically derived compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2830842A Division CA2830842A1 (en) 2005-01-03 2005-12-30 Method for producing probiotically derived compounds

Publications (2)

Publication Number Publication Date
CA2594187A1 CA2594187A1 (en) 2006-07-13
CA2594187C true CA2594187C (en) 2014-01-07

Family

ID=36648071

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2594187A Expired - Fee Related CA2594187C (en) 2005-01-03 2005-12-30 Method for producing probiotically derived compounds
CA2830842A Abandoned CA2830842A1 (en) 2005-01-03 2005-12-30 Method for producing probiotically derived compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2830842A Abandoned CA2830842A1 (en) 2005-01-03 2005-12-30 Method for producing probiotically derived compounds

Country Status (7)

Country Link
US (2) US8530209B2 (https=)
EP (1) EP1836310A4 (https=)
JP (1) JP2008526767A (https=)
CN (1) CN101155923B (https=)
CA (2) CA2594187C (https=)
MX (1) MX2007008155A (https=)
WO (1) WO2006074094A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8530209B2 (en) * 2003-11-26 2013-09-10 Premier Research Labs, Lp Method for producing probiotically derived compounds
WO2007009187A1 (en) * 2005-07-22 2007-01-25 Tarac Technologies Pty Ltd Polyphenol and probiotic containing nutritional supplement
US9944960B2 (en) * 2015-11-17 2018-04-17 Premier Research Labs, Lp Process for microbial production of dihydrolipoic acid and extraction of dihydrolipoic acid with edible oils
US10403413B2 (en) * 2016-09-30 2019-09-03 Varian Medical Systems, Inc. Beam filter assembly and beam filter positioning device

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3037016A (en) * 1959-04-13 1962-05-29 Univ California B12 coenzymes and processes for preparing the same
JPS593197B2 (ja) * 1978-09-25 1984-01-23 十條製紙株式会社 補酵素ｑ↓１↓０の製造法
DE3126021A1 (de) * 1981-07-02 1983-07-28 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung optisch reiner d- oder l-milchsaeure
JP4044975B2 (ja) * 1995-07-25 2008-02-06 株式会社叶匠壽庵 乳酸菌発酵物からなる糖尿病治療剤
US6080401A (en) * 1998-11-19 2000-06-27 Reddy; Malireddy S. Herbal and pharmaceutical drugs enhanced with probiotics
JP3478773B2 (ja) * 1999-12-21 2003-12-15 日東薬品工業株式会社 生菌組成物
WO2001075136A1 (en) 2000-03-31 2001-10-11 Idemitsu Petrochemical Co., Ltd. Process for producing lipids and lipid-secreting microorganisms
US6610530B2 (en) * 2000-07-05 2003-08-26 Danmarks Tekniske Universitet Method of improving biomass yield of lactic acid bacterial cultures
JP4183371B2 (ja) * 2000-08-31 2008-11-19 日本・バイオ株式会社 発酵ウコンの製造法
US20030095959A1 (en) * 2000-11-21 2003-05-22 Access Business Group International Llc. Topical skin composition
US6806069B2 (en) * 2001-01-09 2004-10-19 Pharmachem Laboratories, Inc. Ubiquinone composition and methods related thereto
US20040235123A1 (en) * 2001-04-20 2004-11-25 Liao Hans H Production of alpha-lipoic acid
US6368617B1 (en) * 2001-05-15 2002-04-09 Reliv' International, Inc. Dietary supplement
CN1132927C (zh) * 2001-07-19 2003-12-31 上海交通大学 益生菌真菌共同发酵制备微生态制剂的方法
US8530209B2 (en) * 2003-11-26 2013-09-10 Premier Research Labs, Lp Method for producing probiotically derived compounds
CN100453479C (zh) * 2003-11-26 2009-01-21 杨雄 一种益生菌复合菌剂的制造方法
US8304217B2 (en) * 2003-11-26 2012-11-06 Premier Research Labs, Lp Stabilized dihydrolipoic acid and method of producing same

Also Published As

Publication number Publication date
CN101155923A (zh) 2008-04-02
WO2006074094A3 (en) 2006-10-19
EP1836310A4 (en) 2011-10-19
CA2830842A1 (en) 2006-07-13
WO2006074094A2 (en) 2006-07-13
CN101155923B (zh) 2013-06-05
MX2007008155A (es) 2008-02-20
CA2594187A1 (en) 2006-07-13
US20050118694A1 (en) 2005-06-02
US8530209B2 (en) 2013-09-10
US20140011244A1 (en) 2014-01-09
EP1836310A2 (en) 2007-09-26
JP2008526767A (ja) 2008-07-24

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