CA2589328A1 - Multicyclic bis-amide mmp inhibitors - Google Patents

Multicyclic bis-amide mmp inhibitors Download PDF

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Publication number
CA2589328A1
CA2589328A1 CA002589328A CA2589328A CA2589328A1 CA 2589328 A1 CA2589328 A1 CA 2589328A1 CA 002589328 A CA002589328 A CA 002589328A CA 2589328 A CA2589328 A CA 2589328A CA 2589328 A1 CA2589328 A1 CA 2589328A1
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CA
Canada
Prior art keywords
alkyl
group
optionally substituted
nr10r11
cycloalkyl
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Abandoned
Application number
CA002589328A
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English (en)
French (fr)
Inventor
Timothy Powers
Christoph Steeneck
Ralf Biesinger
Harald Bluhm
Hongbo Deng
Rory Dodd
Brian M. Gallagher, Jr.
Christian Gege
Matthias Hochgurtel
Andrew Kiely
Frank Richter
Mathias Schneider
Irving Sucholeiki
Joshua Van Veldhuizen
Xinyuan Wu
Arthur G. Taveras
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alantos Pharmaceuticals Holding Inc
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Individual
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Filing date
Publication date
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Publication of CA2589328A1 publication Critical patent/CA2589328A1/en
Abandoned legal-status Critical Current

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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
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CA002589328A 2004-12-31 2005-12-31 Multicyclic bis-amide mmp inhibitors Abandoned CA2589328A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US64079504P 2004-12-31 2004-12-31
US60/640,795 2004-12-31
US70626705P 2005-08-08 2005-08-08
US60/706,267 2005-08-08
PCT/US2005/047421 WO2006083454A1 (en) 2004-12-31 2005-12-31 Multicyclic bis-amide mmp inhibitors

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CA2589328A1 true CA2589328A1 (en) 2006-08-10

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CA002589328A Abandoned CA2589328A1 (en) 2004-12-31 2005-12-31 Multicyclic bis-amide mmp inhibitors

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US (1) US20060173183A1 (enExample)
EP (1) EP1843820A1 (enExample)
JP (1) JP2008526761A (enExample)
AU (1) AU2005326659A1 (enExample)
CA (1) CA2589328A1 (enExample)
MX (1) MX2007007895A (enExample)
WO (1) WO2006083454A1 (enExample)

Families Citing this family (36)

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AU2006251989B2 (en) * 2005-05-20 2010-05-27 Alantos-Pharmaceuticals, Inc. Pyrimidine or triazine fused bicyclic metalloprotease inhibitors
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
US20070155737A1 (en) * 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
WO2007079199A2 (en) * 2005-12-30 2007-07-12 Alantos Pharmaceuticals, Holding, Inc. Substituted bis-amide metalloprotease inhibitors
EP2069313A2 (en) * 2006-06-29 2009-06-17 Alantos Pharmaceuticals Holdings, Inc. Metalloprotease inhibitors
ATE528306T1 (de) * 2006-11-02 2011-10-15 Piramal Life Sciences Ltd Benzoxazepin-verbindungen, ihre herstellung und verwendung
US20080221092A1 (en) * 2006-11-20 2008-09-11 Harald Bluhm Heterobicyclic metalloprotease inhibitors
CA2670083A1 (en) * 2006-11-20 2008-05-29 Alantos Pharmaceuticals Holding, Inc. Heterobicyclic metalloprotease inhibitors
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