CA2579821A1 - Capillary ion chromatography - Google Patents
Capillary ion chromatography Download PDFInfo
- Publication number
- CA2579821A1 CA2579821A1 CA002579821A CA2579821A CA2579821A1 CA 2579821 A1 CA2579821 A1 CA 2579821A1 CA 002579821 A CA002579821 A CA 002579821A CA 2579821 A CA2579821 A CA 2579821A CA 2579821 A1 CA2579821 A1 CA 2579821A1
- Authority
- CA
- Canada
- Prior art keywords
- capillary
- tubing
- ion exchange
- packing
- wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004255 ion exchange chromatography Methods 0.000 title claims abstract description 56
- 238000012856 packing Methods 0.000 claims abstract description 63
- 238000005342 ion exchange Methods 0.000 claims abstract description 42
- 230000002378 acidificating effect Effects 0.000 claims abstract description 41
- 239000007788 liquid Substances 0.000 claims abstract description 37
- 238000000034 method Methods 0.000 claims abstract description 37
- 125000000524 functional group Chemical group 0.000 claims abstract description 35
- 239000003014 ion exchange membrane Substances 0.000 claims abstract description 15
- 239000003480 eluent Substances 0.000 claims description 93
- 150000002500 ions Chemical class 0.000 claims description 44
- 239000012492 regenerant Substances 0.000 claims description 30
- 239000002253 acid Substances 0.000 claims description 18
- 238000004587 chromatography analysis Methods 0.000 claims description 15
- 239000012530 fluid Substances 0.000 claims description 15
- 238000004891 communication Methods 0.000 claims description 11
- 239000002245 particle Substances 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 7
- 230000004888 barrier function Effects 0.000 claims description 4
- 238000004064 recycling Methods 0.000 claims description 3
- 239000000758 substrate Substances 0.000 claims 6
- 239000011347 resin Substances 0.000 description 71
- 229920005989 resin Polymers 0.000 description 71
- 238000000926 separation method Methods 0.000 description 51
- 150000001450 anions Chemical class 0.000 description 49
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 49
- 238000005341 cation exchange Methods 0.000 description 35
- HNSDLXPSAYFUHK-UHFFFAOYSA-N 1,4-bis(2-ethylhexyl) sulfosuccinate Chemical class CCCCC(CC)COC(=O)CC(S(O)(=O)=O)C(=O)OCC(CC)CCCC HNSDLXPSAYFUHK-UHFFFAOYSA-N 0.000 description 26
- 239000000243 solution Substances 0.000 description 24
- 230000001629 suppression Effects 0.000 description 23
- 229910001868 water Inorganic materials 0.000 description 23
- 150000001768 cations Chemical class 0.000 description 22
- 239000008367 deionised water Substances 0.000 description 21
- 229910021641 deionized water Inorganic materials 0.000 description 21
- 238000004458 analytical method Methods 0.000 description 17
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 15
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 14
- 239000003729 cation exchange resin Substances 0.000 description 14
- 238000001514 detection method Methods 0.000 description 14
- 239000012528 membrane Substances 0.000 description 13
- 239000012508 resin bead Substances 0.000 description 13
- 229920000557 Nafion® Polymers 0.000 description 12
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 11
- 229910001414 potassium ion Inorganic materials 0.000 description 11
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 10
- 239000000126 substance Substances 0.000 description 9
- 239000012491 analyte Substances 0.000 description 8
- 230000008569 process Effects 0.000 description 8
- 229910019142 PO4 Inorganic materials 0.000 description 7
- 238000006460 hydrolysis reaction Methods 0.000 description 7
- 229940098779 methanesulfonic acid Drugs 0.000 description 7
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 7
- 239000010452 phosphate Substances 0.000 description 7
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 6
- 239000004696 Poly ether ether ketone Substances 0.000 description 6
- 230000008901 benefit Effects 0.000 description 6
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 description 6
- 238000013375 chromatographic separation Methods 0.000 description 6
- -1 hydroxide ions Chemical class 0.000 description 6
- 229920002530 polyetherether ketone Polymers 0.000 description 6
- 230000008929 regeneration Effects 0.000 description 6
- 238000011069 regeneration method Methods 0.000 description 6
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 5
- 125000002091 cationic group Chemical group 0.000 description 5
- 238000005868 electrolysis reaction Methods 0.000 description 5
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 4
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 4
- 229910002651 NO3 Inorganic materials 0.000 description 4
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000003456 ion exchange resin Substances 0.000 description 4
- 229920003303 ion-exchange polymer Polymers 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 150000007513 acids Chemical class 0.000 description 3
- 239000003957 anion exchange resin Substances 0.000 description 3
- 125000000129 anionic group Chemical group 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000000356 contaminant Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 239000000178 monomer Substances 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 230000032258 transport Effects 0.000 description 3
- CHRJZRDFSQHIFI-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;styrene Chemical class C=CC1=CC=CC=C1.C=CC1=CC=CC=C1C=C CHRJZRDFSQHIFI-UHFFFAOYSA-N 0.000 description 2
- 101150030235 CTC1 gene Proteins 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- XTEGARKTQYYJKE-UHFFFAOYSA-M Chlorate Chemical compound [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 2
- 229910006069 SO3H Inorganic materials 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- CBMCZKMIOZYAHS-NSCUHMNNSA-N [(e)-prop-1-enyl]boronic acid Chemical compound C\C=C\B(O)O CBMCZKMIOZYAHS-NSCUHMNNSA-N 0.000 description 2
- 150000001449 anionic compounds Chemical class 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 229940023913 cation exchange resins Drugs 0.000 description 2
- 229920001429 chelating resin Polymers 0.000 description 2
- 238000013480 data collection Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000010559 graft polymerization reaction Methods 0.000 description 2
- 239000012510 hollow fiber Substances 0.000 description 2
- 230000004941 influx Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 229910052744 lithium Inorganic materials 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 230000008384 membrane barrier Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-O oxonium Chemical compound [OH3+] XLYOFNOQVPJJNP-UHFFFAOYSA-O 0.000 description 2
- 229910052697 platinum Inorganic materials 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 238000005349 anion exchange Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-M bromate Inorganic materials [O-]Br(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-M 0.000 description 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-N bromic acid Chemical compound OBr(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-N 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 238000004850 capillary HPLC Methods 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 150000005323 carbonate salts Chemical class 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229910001919 chlorite Inorganic materials 0.000 description 1
- 229910052619 chlorite group Inorganic materials 0.000 description 1
- AOGYCOYQMAVAFD-UHFFFAOYSA-N chlorocarbonic acid Chemical compound OC(Cl)=O AOGYCOYQMAVAFD-UHFFFAOYSA-N 0.000 description 1
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 239000005350 fused silica glass Substances 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- NBZBKCUXIYYUSX-UHFFFAOYSA-N iminodiacetic acid Chemical group OC(=O)CNCC(O)=O NBZBKCUXIYYUSX-UHFFFAOYSA-N 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000003317 industrial substance Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 229910001412 inorganic anion Inorganic materials 0.000 description 1
- 239000012500 ion exchange media Substances 0.000 description 1
- 230000037427 ion transport Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 150000002891 organic anions Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N phosphonic acid group Chemical group P(O)(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 239000002352 surface water Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/367—Ion-suppression
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
- G01N2030/965—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange suppressor columns
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/944,442 | 2004-09-16 | ||
| US10/944,442 US8216515B2 (en) | 2004-09-16 | 2004-09-16 | Capillary ion chromatography |
| PCT/US2005/033459 WO2006034182A1 (en) | 2004-09-16 | 2005-09-15 | Capillary ion chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2579821A1 true CA2579821A1 (en) | 2006-03-30 |
Family
ID=35717657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002579821A Abandoned CA2579821A1 (en) | 2004-09-16 | 2005-09-15 | Capillary ion chromatography |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8216515B2 (enExample) |
| EP (1) | EP1789780B1 (enExample) |
| JP (2) | JP5055121B2 (enExample) |
| KR (1) | KR101256401B1 (enExample) |
| CN (1) | CN101044399B (enExample) |
| AU (1) | AU2005286938B2 (enExample) |
| CA (1) | CA2579821A1 (enExample) |
| WO (1) | WO2006034182A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7618826B2 (en) * | 2006-09-19 | 2009-11-17 | Dionex Corporation | Membrane suppressor with an outlet substantially non-retentive for ionic species |
| US7964411B2 (en) * | 2007-06-12 | 2011-06-21 | Dionex Corporation | Membrane based concentrators |
| US7632404B2 (en) * | 2007-11-15 | 2009-12-15 | Dionex Corporation | Barrier with a seated ion exchange bead and method |
| US8425842B2 (en) | 2008-01-07 | 2013-04-23 | Shimadzu Corporation | Suppressor and ion chromatograph employing the same |
| US8597571B2 (en) * | 2008-01-28 | 2013-12-03 | Dionex Corporation | Electrolytic eluent recycle device, apparatus and method of use |
| US8133373B2 (en) * | 2008-08-15 | 2012-03-13 | Dionex Corporation | Electrochemically driven pump |
| US9188573B2 (en) | 2010-01-20 | 2015-11-17 | Dionex Corporation | Multichannel ion chromatography system and method |
| WO2011132518A1 (ja) * | 2010-04-21 | 2011-10-27 | 日理工業株式会社 | 高純度電解質溶液生成装置 |
| US8414684B2 (en) | 2010-06-01 | 2013-04-09 | Dionex Corporation | High pressure degas assembly for chromatography system and method |
| TWI434725B (zh) * | 2011-03-08 | 2014-04-21 | Asia Union Electronical Chemical Corp | 利用氫氧基化合物和離子交換樹脂吸附以純化氟酸系蝕刻液的處理方法 |
| US8529758B2 (en) | 2011-03-22 | 2013-09-10 | Dionex Corporation | CO2-removal device and method |
| US9086426B2 (en) * | 2012-09-12 | 2015-07-21 | Dionex Corporation | Multi-component eluent generating system and method |
| US10048233B2 (en) | 2012-11-12 | 2018-08-14 | Dionex Corporation | Suppressor device |
| CN102967680B (zh) * | 2012-11-26 | 2014-12-10 | 中国科学院青岛生物能源与过程研究所 | 一种毛细管离子色谱质谱联用分析系统 |
| US10802000B2 (en) | 2013-03-15 | 2020-10-13 | Dionex Corporation | Method of calibrating a chromatography system |
| US9914651B2 (en) | 2013-05-08 | 2018-03-13 | Dionex Corporation | Current efficient electrolytic device and method |
| US9964510B2 (en) | 2013-09-16 | 2018-05-08 | Dionex Corporation | Electrolytic four-channel device and method |
| US9400268B2 (en) | 2014-08-08 | 2016-07-26 | Dionex Corporation | Method for reducing suppressor noise |
| US9804136B2 (en) | 2014-09-18 | 2017-10-31 | Dionex Corporation | Automated method of calibrating a chromatography system and analysis of a sample |
| US20160137530A1 (en) | 2014-11-13 | 2016-05-19 | Dionex Corporation | Ion exchange based volatile component removal device for ion chromatography |
| US10175211B2 (en) | 2014-12-31 | 2019-01-08 | Dionex Corporation | Current-efficient suppressor and pretreatment device and method |
| US10641751B2 (en) | 2015-06-19 | 2020-05-05 | Dionex Corporation | Ion exchange chromatography column, method, and system thereof |
| CN106885868A (zh) * | 2015-12-16 | 2017-06-23 | 鞍钢股份有限公司 | 一种检测钢铁工业用水中无机阴离子和阳离子含量的方法 |
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2004
- 2004-09-16 US US10/944,442 patent/US8216515B2/en active Active
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2005
- 2005-09-15 AU AU2005286938A patent/AU2005286938B2/en not_active Ceased
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- 2005-09-15 EP EP05797580.7A patent/EP1789780B1/en not_active Expired - Lifetime
- 2005-09-15 WO PCT/US2005/033459 patent/WO2006034182A1/en not_active Ceased
- 2005-09-15 CA CA002579821A patent/CA2579821A1/en not_active Abandoned
- 2005-09-15 KR KR1020077008518A patent/KR101256401B1/ko not_active Expired - Fee Related
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2011
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2012
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- 2013-03-06 US US13/787,296 patent/US9283495B2/en not_active Expired - Fee Related
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| EP1789780A1 (en) | 2007-05-30 |
| KR20070053344A (ko) | 2007-05-23 |
| JP5801126B2 (ja) | 2015-10-28 |
| CN101044399B (zh) | 2014-03-19 |
| AU2005286938A1 (en) | 2006-03-30 |
| JP2011232351A (ja) | 2011-11-17 |
| US20120228227A1 (en) | 2012-09-13 |
| KR101256401B1 (ko) | 2013-04-30 |
| WO2006034182A1 (en) | 2006-03-30 |
| JP2008513790A (ja) | 2008-05-01 |
| JP5055121B2 (ja) | 2012-10-24 |
| US8415168B2 (en) | 2013-04-09 |
| US20060057733A1 (en) | 2006-03-16 |
| US20130180922A1 (en) | 2013-07-18 |
| EP1789780B1 (en) | 2016-11-02 |
| CN101044399A (zh) | 2007-09-26 |
| US8216515B2 (en) | 2012-07-10 |
| AU2005286938B2 (en) | 2011-06-30 |
| US9283495B2 (en) | 2016-03-15 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20170510 |