CA2573456A1 - Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers - Google Patents
Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers Download PDFInfo
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- CA2573456A1 CA2573456A1 CA002573456A CA2573456A CA2573456A1 CA 2573456 A1 CA2573456 A1 CA 2573456A1 CA 002573456 A CA002573456 A CA 002573456A CA 2573456 A CA2573456 A CA 2573456A CA 2573456 A1 CA2573456 A1 CA 2573456A1
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- liver
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- liver disease
- antioxidant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04103318 | 2004-07-13 | ||
| EP04103318.4 | 2004-07-13 | ||
| PCT/EP2005/053338 WO2006005759A2 (en) | 2004-07-13 | 2005-07-12 | Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2573456A1 true CA2573456A1 (en) | 2006-01-19 |
Family
ID=34929318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002573456A Abandoned CA2573456A1 (en) | 2004-07-13 | 2005-07-12 | Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20070225255A1 (ja) |
| EP (1) | EP1765413A2 (ja) |
| JP (1) | JP2008506667A (ja) |
| CN (1) | CN1997403A (ja) |
| AU (1) | AU2005261654A1 (ja) |
| CA (1) | CA2573456A1 (ja) |
| IL (1) | IL179738A0 (ja) |
| RU (1) | RU2007105138A (ja) |
| SG (1) | SG156613A1 (ja) |
| WO (1) | WO2006005759A2 (ja) |
| ZA (1) | ZA200609635B (ja) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1718283T3 (da) | 2004-01-22 | 2013-04-22 | Univ Miami | Topisk co-enzyme Q10 formuleringer og fremgangsmåder for anvendelse. |
| US20080032940A1 (en) * | 2006-08-07 | 2008-02-07 | Balaraman Kalyanaraman | Methods for reducing anthracycline-induced toxicity |
| US8557733B2 (en) | 2006-10-20 | 2013-10-15 | Mitotech S.A. | Composition for regenerating and stimulating growth of plants and for adapting plants to different stress factors |
| EP2119436A4 (en) | 2006-10-20 | 2010-03-03 | Ltd Liability Company Mitotech | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF EYE DISEASES |
| WO2008094061A1 (fr) * | 2007-01-29 | 2008-08-07 | Limited Liability Company 'mitotechnology' | Compositions pharmaceutiques et cosmétiques servant à accélérer le processus de cicatrisation de plaies et autres lésions superficielles |
| US8349902B2 (en) * | 2007-01-29 | 2013-01-08 | Mitotech Sa | Pharmaceutical compositions useful for preventing and treating oncological diseases |
| US9439916B2 (en) | 2007-04-11 | 2016-09-13 | Mitotech Sa | Composition for decelerating the aging in the organism and for extending the life time thereof and the use of said composition |
| US8518915B2 (en) | 2007-06-29 | 2013-08-27 | Mitotech Sa | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases |
| US20100179106A1 (en) * | 2007-09-07 | 2010-07-15 | Gencia Corporation | Mitochondrial compositions and uses thereof |
| US8388936B2 (en) * | 2008-02-22 | 2013-03-05 | Mcw Research Foundation, Inc. | In vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging |
| US8388931B2 (en) * | 2008-02-29 | 2013-03-05 | Marcos Lopez | 99m Tc-labeled triphenylphosphonium derivative contrasting agents and molecular probes for early detection and imaging of breast tumors |
| WO2009126764A1 (en) | 2008-04-11 | 2009-10-15 | Cytotech Labs, Llc | Methods and use of inducing apoptosis in cancer cells |
| WO2010056145A1 (ru) | 2008-11-12 | 2010-05-20 | Общество С Ограниченной Ответственностью "Митотехнология" | Способ умеренного повышения протонной проводимости биологических мембран при помощи митохондриально- адресованных делокализованных катионов |
| CN102438615A (zh) * | 2009-04-17 | 2012-05-02 | 科尔比制药公司 | 包含氧化应激调节剂(osm)的药学活性组合物、新的化学实体、组合物和用途 |
| JP2012526828A (ja) | 2009-05-11 | 2012-11-01 | バーグ バイオシステムズ，エルエルシー | エピメタボリックシフター、多次元細胞内分子、または環境影響因子を使用する代謝性障害の治療方法 |
| EP2441453B1 (en) | 2009-06-10 | 2014-11-26 | Mitotech SA | Pharmaceutical composition for use in medical and veterinary ophthalmology |
| KR20120125980A (ko) | 2009-11-13 | 2012-11-19 | 리미티드 라이어빌러티 컴퍼니 미토테크 | 미토콘드리아 표적화된 항산화제에 기초한 약학적 물질 |
| ES2762451T3 (es) | 2011-04-04 | 2020-05-25 | Berg Llc | Tratamiento de tumores del sistema nervioso central con coenzima Q10 |
| EA031399B1 (ru) | 2011-06-03 | 2018-12-28 | Общество С Ограниченной Ответственностью "Митотех" | Изготовление и использование пероральных фармацевтических композиций на основе митохондриально-адресованных антиоксидантов |
| AU2012312654B2 (en) | 2011-09-19 | 2017-04-13 | Gencia Corporation | Modified creatine compounds |
| EA032775B1 (ru) | 2013-04-08 | 2019-07-31 | Берг Ллк | Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10 |
| WO2014173374A1 (en) * | 2013-04-24 | 2014-10-30 | Smart Brain s.r.o. | Tamoxifen derivatives for treatment of neoplastic diseases, especially with high her2 protein level |
| JP6595478B2 (ja) | 2013-09-04 | 2019-10-23 | バーグ エルエルシー | コエンザイムｑ１０の連続注入によるがんの治療方法 |
| US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
| KR101773404B1 (ko) | 2015-08-25 | 2017-08-31 | (주) 씨유스킨 | 자외선에 의한 피부 손상의 예방 또는 개선을 위한 화장료 조성물 |
| CN107510848A (zh) * | 2016-06-15 | 2017-12-26 | 常州莱道斯生物医药科技有限公司 | 线粒体靶向制剂MitoPBN在防治糖尿病中的应用 |
| CN108201543A (zh) * | 2016-12-19 | 2018-06-26 | 北京福纳康生物技术有限公司 | 水溶性富勒烯结构在制备治疗脂肪肝的药物中的应用 |
| CN115381804B (zh) * | 2022-08-10 | 2024-06-21 | 华南师大(清远)科技创新研究院有限公司 | 癸基泛醌在制备治疗肝纤维化药物中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9722361D0 (en) * | 1997-10-24 | 1997-12-17 | Pharma Nord Uk Ltd | Pharmaceutical formulation for treating liver disorders |
| US6331532B1 (en) * | 1998-11-25 | 2001-12-18 | University Of Otago | Mitochondrially targeted antioxidants |
| WO2005019233A1 (en) * | 2003-08-22 | 2005-03-03 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| CA2354743A1 (en) * | 2001-08-07 | 2003-02-07 | University Of Otago | Mitochondrially targeted antioxidants |
| NZ513547A (en) * | 2001-08-13 | 2002-09-27 | Antipodean Biotechnology Ltd | Synthesis of triphenylphosphonium quinols (e.g. mitoquinol) and/or quinones (e.g. mitoquinone) |
-
2005
- 2005-07-12 RU RU2007105138/15A patent/RU2007105138A/ru unknown
- 2005-07-12 JP JP2007520833A patent/JP2008506667A/ja not_active Withdrawn
- 2005-07-12 EP EP05775873A patent/EP1765413A2/en not_active Withdrawn
- 2005-07-12 WO PCT/EP2005/053338 patent/WO2006005759A2/en active Application Filing
- 2005-07-12 CN CNA2005800231931A patent/CN1997403A/zh active Pending
- 2005-07-12 CA CA002573456A patent/CA2573456A1/en not_active Abandoned
- 2005-07-12 AU AU2005261654A patent/AU2005261654A1/en not_active Abandoned
- 2005-07-12 SG SG200906579-8A patent/SG156613A1/en unknown
- 2005-07-12 US US11/632,149 patent/US20070225255A1/en not_active Abandoned
-
2006
- 2006-11-20 ZA ZA200609635A patent/ZA200609635B/xx unknown
- 2006-11-30 IL IL179738A patent/IL179738A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006005759A3 (en) | 2006-05-11 |
| IL179738A0 (en) | 2007-05-15 |
| JP2008506667A (ja) | 2008-03-06 |
| CN1997403A (zh) | 2007-07-11 |
| ZA200609635B (en) | 2008-08-27 |
| SG156613A1 (en) | 2009-11-26 |
| AU2005261654A1 (en) | 2006-01-19 |
| RU2007105138A (ru) | 2008-08-20 |
| WO2006005759A2 (en) | 2006-01-19 |
| US20070225255A1 (en) | 2007-09-27 |
| EP1765413A2 (en) | 2007-03-28 |
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| FZDE | Discontinued |