CA2569134C - Ultrasound contrast agent dosage formulation - Google Patents

Ultrasound contrast agent dosage formulation Download PDF

Info

Publication number
CA2569134C
CA2569134C CA2569134A CA2569134A CA2569134C CA 2569134 C CA2569134 C CA 2569134C CA 2569134 A CA2569134 A CA 2569134A CA 2569134 A CA2569134 A CA 2569134A CA 2569134 C CA2569134 C CA 2569134C
Authority
CA
Canada
Prior art keywords
dosage formulation
microspheres
microparticles
suspension
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2569134A
Other languages
English (en)
French (fr)
Other versions
CA2569134A1 (en
Inventor
Richard Walovitch
Howard Bernstein
Donald E. Chickering, Iii
Julie Straub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acusphere Inc
Original Assignee
Acusphere Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acusphere Inc filed Critical Acusphere Inc
Publication of CA2569134A1 publication Critical patent/CA2569134A1/en
Application granted granted Critical
Publication of CA2569134C publication Critical patent/CA2569134C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
CA2569134A 2004-06-04 2004-06-04 Ultrasound contrast agent dosage formulation Expired - Fee Related CA2569134C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2004/017813 WO2005120587A1 (en) 2004-06-04 2004-06-04 Ultrasound contrast agent dosage formulation

Publications (2)

Publication Number Publication Date
CA2569134A1 CA2569134A1 (en) 2005-12-22
CA2569134C true CA2569134C (en) 2010-11-23

Family

ID=34958128

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2569134A Expired - Fee Related CA2569134C (en) 2004-06-04 2004-06-04 Ultrasound contrast agent dosage formulation

Country Status (10)

Country Link
JP (1) JP4808214B2 (zh)
CN (1) CN1993147B (zh)
AU (1) AU2004320514B8 (zh)
BR (1) BRPI0418879A (zh)
CA (1) CA2569134C (zh)
IL (2) IL179594A (zh)
MX (1) MXPA06014111A (zh)
NO (1) NO20070070L (zh)
RU (1) RU2344833C2 (zh)
WO (1) WO2005120587A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9630028B2 (en) * 2006-08-11 2017-04-25 Koninklijke Philips N.V. Ultrasound system for cerebral blood flow imaging and microbubble-enhanced blood clot lysis
KR101061224B1 (ko) * 2008-10-08 2011-08-31 포항공과대학교 산학협력단 X 선을 이용한 유동정보 측정용 캡슐
US8784800B2 (en) 2009-03-09 2014-07-22 Medtronic, Inc. Method of delivering cell therapy to a target site
US9757462B2 (en) 2010-11-19 2017-09-12 Sapporo Medical University Combined pharmaceutical preparation
EP2844362B1 (en) * 2012-04-30 2020-02-26 Ge Healthcare As Method for filling a container with a foamable composition
ES2821966T3 (es) 2014-04-02 2021-04-28 Nitto Denko Corp Molécula de direccionamiento derivada de RBP y utilización de la misma
ES2890328T3 (es) * 2015-04-20 2022-01-18 Univ California Gas encapsulado o material de contraste de CT de vacío parcial
RU2620758C1 (ru) * 2016-07-13 2017-05-29 Федеральное государственное бюджетное научное учреждение "Научный центр неврологии" (ФГБНУ НЦН) Способ количественного определения микрососудов в атеросклеротической бляшке сонных артерий
CN111419181B (zh) * 2020-03-31 2023-07-25 浙江大学 一种用于小动物长时间活体成像的装置及其使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6146657A (en) * 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
US5773024A (en) * 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
CN1068229C (zh) * 1993-12-15 2001-07-11 勃勒柯研究有限公司 超声对比介质、含该介质的对比剂及方法
DE4406474A1 (de) * 1994-02-23 1995-08-24 Schering Ag Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel
DE69729088T2 (de) * 1996-03-05 2005-05-12 Acusphere, Inc., Cambridge Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel
US5976501A (en) * 1996-06-07 1999-11-02 Molecular Biosystems, Inc. Use of pressure resistant protein microspheres encapsulating gases as ultrasonic imaging agents for vascular perfusion
US5837221A (en) * 1996-07-29 1998-11-17 Acusphere, Inc. Polymer-lipid microencapsulated gases for use as imaging agents
US6045777A (en) * 1997-06-30 2000-04-04 Acusphere, Inc. Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases

Also Published As

Publication number Publication date
RU2344833C2 (ru) 2009-01-27
JP4808214B2 (ja) 2011-11-02
IL213897A0 (en) 2011-07-31
JP2008501684A (ja) 2008-01-24
IL179594A0 (en) 2007-05-15
CN1993147A (zh) 2007-07-04
CN1993147B (zh) 2013-03-06
WO2005120587A1 (en) 2005-12-22
AU2004320514B2 (en) 2009-08-06
IL213897A (en) 2013-07-31
IL179594A (en) 2011-08-31
MXPA06014111A (es) 2007-03-07
CA2569134A1 (en) 2005-12-22
RU2006147232A (ru) 2008-07-20
NO20070070L (no) 2007-03-05
AU2004320514B8 (en) 2009-08-27
BRPI0418879A (pt) 2007-11-27
AU2004320514A1 (en) 2005-12-22

Similar Documents

Publication Publication Date Title
US8586005B2 (en) Ultrasound contrast agent dosage formulation
CA2260938C (en) Polymer-lipid microencapsulated gases for use as imaging agents
EP0996470B1 (en) Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases
IL179594A (en) Ultrasound contrast agent dosage formulation
KR19990087529A (ko) 영상화제로사용되는마이크로캡슐화된불소첨가가스
JP2001524983A (ja) 新規の音響活性薬剤輸送系
JP2011140527A (ja) 超音波造影剤の投薬処方物
EP1609483B1 (en) Ultrasound contrast agent dosage formulation
NZ551986A (en) Ultrasound contrast agent dosage formulation
ZA200609760B (en) Ultrasound contrast agent dosage formulation
KR20070039027A (ko) 초음파 조영제 투약 제형
CN102600485B (zh) 超声对比剂剂量配方

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20170605