CA2550155C - Hla-dr-specific antibodies, compositions and methods - Google Patents
Hla-dr-specific antibodies, compositions and methods Download PDFInfo
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- CA2550155C CA2550155C CA2550155A CA2550155A CA2550155C CA 2550155 C CA2550155 C CA 2550155C CA 2550155 A CA2550155 A CA 2550155A CA 2550155 A CA2550155 A CA 2550155A CA 2550155 C CA2550155 C CA 2550155C
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60894403P | 2003-12-15 | 2003-12-15 | |
| US60/608,944 | 2003-12-15 | ||
| PCT/US2004/042312 WO2005058251A2 (en) | 2003-12-15 | 2004-12-15 | Hla-dr-specific antibodies, compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2550155A1 CA2550155A1 (en) | 2005-06-30 |
| CA2550155C true CA2550155C (en) | 2015-03-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2550155A Expired - Fee Related CA2550155C (en) | 2003-12-15 | 2004-12-15 | Hla-dr-specific antibodies, compositions and methods |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8354507B2 (enExample) |
| EP (1) | EP1711527A4 (enExample) |
| JP (1) | JP2007513976A (enExample) |
| CA (1) | CA2550155C (enExample) |
| WO (1) | WO2005058251A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2625222A1 (en) * | 2005-10-11 | 2007-04-19 | Domantis Limited | Antibody polypeptide library screening and selected antibody polypeptides |
| GB0525214D0 (en) * | 2005-12-12 | 2006-01-18 | Bioinvent Int Ab | Biological materials and uses thereof |
| US9085614B2 (en) * | 2008-08-01 | 2015-07-21 | Immunas Pharma, Inc. | Antibodies that specifically bind to Aβ oligomers and uses thereof |
| WO2011156328A1 (en) * | 2010-06-08 | 2011-12-15 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
| KR102096224B1 (ko) | 2011-10-28 | 2020-04-03 | 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 | 폴리펩티드 구축물 및 이의 용도 |
| KR20150132581A (ko) * | 2013-12-31 | 2015-11-25 | 재단법인 생물기술개발중심 | 항-vegf 항체 및 그것의 용도 |
| AU2016270474A1 (en) * | 2015-06-04 | 2018-01-04 | University Of Southern California | Lym-1 and Lym-2 targeted CAR cell immunotherapy |
| BR112018012344A2 (pt) * | 2015-12-17 | 2018-12-04 | Janssen Biotech Inc | anticorpos que se ligam especificamente a hla-dr e seus usos |
| JP7224289B2 (ja) | 2016-09-21 | 2023-02-17 | アプティーボ リサーチ アンド デベロップメント エルエルシー | Ｃｄ１２３結合タンパク質並びに関連する組成物及び方法 |
| JP2020501512A (ja) * | 2016-09-23 | 2020-01-23 | ユニバーシティ オブ サザン カリフォルニア | キメラ抗原受容体およびその組成物ならびにそれらの使用の方法 |
| KR102869563B1 (ko) | 2017-07-17 | 2025-10-10 | 얀센 바이오테크 인코포레이티드 | 피브로넥틴 iii형 도메인에 대한 항원 결합 영역 및 이의 사용 방법 |
| JP2022520106A (ja) | 2019-02-15 | 2022-03-28 | ユニバーシティ オブ サザン カリフォルニア | Ｌｙｍ－１およびｌｙｍ－２抗体組成物ならびに改善されたｃａｒ構築物 |
| WO2020204054A1 (en) * | 2019-04-01 | 2020-10-08 | Chugai Seiyaku Kabushiki Kaisha | Anti-hla-dq2.5 antibody |
| CN115028730B (zh) * | 2022-05-17 | 2022-11-08 | 诺赛联合(北京)生物医学科技有限公司 | 一种成体干细胞衍生的类器官制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0698021B2 (ja) | 1986-08-01 | 1994-12-07 | 帝人株式会社 | マウス−ヒトキメラ抗体、それをコ−ドする発現型キメラｄｎａ配列、プラスミド及び細胞 |
| NO873164L (no) | 1986-07-30 | 1988-02-01 | Teijin Ltd | Muse-humane kimaere antistoffer. |
| US6180377B1 (en) * | 1993-06-16 | 2001-01-30 | Celltech Therapeutics Limited | Humanized antibodies |
| PT877626E (pt) | 1996-01-23 | 2003-01-31 | Univ Vermont And State Agric C | Anticorpos anti-cd1s para utilizacao contra icto |
| JP4481489B2 (ja) * | 1998-01-23 | 2010-06-16 | エフ．ホフマン−ラ ロシュ アーゲー | ヒトｉｌ−１２に対する抗体 |
| WO2000012560A1 (en) * | 1998-08-28 | 2000-03-09 | Dendreon Corporation | Selective apoptosis of neoplastic cells by an hla-dr specific monoclonal antibody |
| CA2362592A1 (en) * | 1999-02-12 | 2000-08-17 | Genetics Institute, Inc. | Humanized immunoglobulin reactive with b7 molecules and methods of treatment therewith |
| EP1156060B1 (en) | 2000-05-12 | 2007-06-27 | GPC Biotech AG | Human peptides/proteins causing or leading to the killing of cells including lymphoid tumor cells |
| KR20050036852A (ko) * | 2001-10-15 | 2005-04-20 | 기린 비루 가부시키가이샤 | 항-ｈｌａ-ｄｒ 항체 |
| PT1461428E (pt) * | 2001-12-03 | 2012-05-29 | Alexion Pharma Inc | Método para produção de anticorpos híbridos |
| US8450348B2 (en) * | 2007-02-21 | 2013-05-28 | Forma Tm, Llc | Derivatives of squaric acid with anti-proliferative activity |
-
2004
- 2004-12-15 WO PCT/US2004/042312 patent/WO2005058251A2/en not_active Ceased
- 2004-12-15 US US11/013,537 patent/US8354507B2/en not_active Expired - Fee Related
- 2004-12-15 CA CA2550155A patent/CA2550155C/en not_active Expired - Fee Related
- 2004-12-15 EP EP04814490A patent/EP1711527A4/en not_active Ceased
- 2004-12-15 JP JP2006544134A patent/JP2007513976A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007513976A (ja) | 2007-05-31 |
| US20050208048A1 (en) | 2005-09-22 |
| EP1711527A4 (en) | 2008-09-03 |
| WO2005058251A3 (en) | 2005-11-17 |
| WO2005058251A2 (en) | 2005-06-30 |
| EP1711527A2 (en) | 2006-10-18 |
| US8354507B2 (en) | 2013-01-15 |
| CA2550155A1 (en) | 2005-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20181217 |