CA2542835A1 - Inhibition a mediation d'interference d'arn de l'expression genetique a l'aide d'acide nucleique d'interference court (sina) - Google Patents

Inhibition a mediation d'interference d'arn de l'expression genetique a l'aide d'acide nucleique d'interference court (sina) Download PDF

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Publication number
CA2542835A1
CA2542835A1 CA002542835A CA2542835A CA2542835A1 CA 2542835 A1 CA2542835 A1 CA 2542835A1 CA 002542835 A CA002542835 A CA 002542835A CA 2542835 A CA2542835 A CA 2542835A CA 2542835 A1 CA2542835 A1 CA 2542835A1
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CA
Canada
Prior art keywords
nucleotides
sina
sina molecule
molecule
rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002542835A
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English (en)
Inventor
Peter Haeberli
James Mcswiggen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sirna Therapeutics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/693,059 external-priority patent/US20080039414A1/en
Priority claimed from US10/720,448 external-priority patent/US8273866B2/en
Priority claimed from US10/727,780 external-priority patent/US20050233329A1/en
Priority claimed from US10/757,803 external-priority patent/US20050020525A1/en
Priority claimed from US10/780,447 external-priority patent/US7491805B2/en
Priority claimed from US10/826,966 external-priority patent/US20050032733A1/en
Priority claimed from PCT/US2004/013456 external-priority patent/WO2005041859A2/fr
Priority claimed from PCT/US2004/016390 external-priority patent/WO2005019453A2/fr
Application filed by Individual filed Critical Individual
Publication of CA2542835A1 publication Critical patent/CA2542835A1/fr
Abandoned legal-status Critical Current

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    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
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    • C12N15/1135Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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CA002542835A 2003-10-23 2004-08-20 Inhibition a mediation d'interference d'arn de l'expression genetique a l'aide d'acide nucleique d'interference court (sina) Abandoned CA2542835A1 (fr)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US10/693,059 US20080039414A1 (en) 2002-02-20 2003-10-23 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US10/693,059 2003-10-23
US10/720,448 2003-11-24
US10/720,448 US8273866B2 (en) 2002-02-20 2003-11-24 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
US10/727,780 US20050233329A1 (en) 2002-02-20 2003-12-03 Inhibition of gene expression using duplex forming oligonucleotides
US10/727,780 2003-12-03
US10/757,803 US20050020525A1 (en) 2002-02-20 2004-01-14 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US10/757,803 2004-01-14
US54348004P 2004-02-10 2004-02-10
US60/543,480 2004-02-10
US10/780,447 2004-02-13
US10/780,447 US7491805B2 (en) 2001-05-18 2004-02-13 Conjugates and compositions for cellular delivery
US10/826,966 US20050032733A1 (en) 2001-05-18 2004-04-16 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
US10/826,966 2004-04-16
USPCT/US04/13456 2004-04-30
PCT/US2004/013456 WO2005041859A2 (fr) 2003-04-30 2004-04-30 Conjugues et compositions
USPCT/US04/16390 2004-05-24
PCT/US2004/016390 WO2005019453A2 (fr) 2001-05-18 2004-05-24 Interference arn a mediation assuree par l'inhibition de genes au moyen de petit acide nucleique interferent (ansi) modifie chimiquement
PCT/US2004/027403 WO2005044981A2 (fr) 2003-10-23 2004-08-20 Inhibition a mediation d'interference d'arn de l'expression genetique a l'aide d'acide nucleique d'interference court (sina)

Publications (1)

Publication Number Publication Date
CA2542835A1 true CA2542835A1 (fr) 2005-05-19

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Family Applications (2)

Application Number Title Priority Date Filing Date
CA002542835A Abandoned CA2542835A1 (fr) 2003-10-23 2004-08-20 Inhibition a mediation d'interference d'arn de l'expression genetique a l'aide d'acide nucleique d'interference court (sina)
CA002543013A Abandoned CA2543013A1 (fr) 2003-10-23 2004-08-20 Inhibition mediee par interference arn de l'expression genique de nogo et du recepteur nogo au moyen d'un petit acide nucleique interferent (sina)

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002543013A Abandoned CA2543013A1 (fr) 2003-10-23 2004-08-20 Inhibition mediee par interference arn de l'expression genique de nogo et du recepteur nogo au moyen d'un petit acide nucleique interferent (sina)

Country Status (4)

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EP (3) EP1675949A2 (fr)
JP (2) JP2008506351A (fr)
CA (2) CA2542835A1 (fr)
WO (3) WO2005044981A2 (fr)

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