CA2533707A1 - Treatment of lesions of the soft tissues - Google Patents
Treatment of lesions of the soft tissues Download PDFInfo
- Publication number
- CA2533707A1 CA2533707A1 CA002533707A CA2533707A CA2533707A1 CA 2533707 A1 CA2533707 A1 CA 2533707A1 CA 002533707 A CA002533707 A CA 002533707A CA 2533707 A CA2533707 A CA 2533707A CA 2533707 A1 CA2533707 A1 CA 2533707A1
- Authority
- CA
- Canada
- Prior art keywords
- granules
- combination
- weight percent
- range
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000003902 lesion Effects 0.000 title claims description 18
- 210000004872 soft tissue Anatomy 0.000 title claims description 13
- 238000011282 treatment Methods 0.000 title description 29
- 206010061218 Inflammation Diseases 0.000 claims abstract description 23
- 230000004054 inflammatory process Effects 0.000 claims abstract description 22
- 230000001338 necrotic effect Effects 0.000 claims abstract description 10
- 239000008187 granular material Substances 0.000 claims description 75
- 206010052428 Wound Diseases 0.000 claims description 39
- 208000027418 Wounds and injury Diseases 0.000 claims description 39
- 238000000034 method Methods 0.000 claims description 37
- 150000001875 compounds Chemical class 0.000 claims description 29
- 230000002727 hyperosmolar Effects 0.000 claims description 23
- 239000000203 mixture Substances 0.000 claims description 23
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 20
- 239000003963 antioxidant agent Substances 0.000 claims description 20
- 235000002639 sodium chloride Nutrition 0.000 claims description 19
- 229920000642 polymer Polymers 0.000 claims description 18
- 230000003078 antioxidant effect Effects 0.000 claims description 14
- 239000011780 sodium chloride Substances 0.000 claims description 14
- 238000002560 therapeutic procedure Methods 0.000 claims description 13
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 10
- 239000013538 functional additive Substances 0.000 claims description 10
- 229920001577 copolymer Polymers 0.000 claims description 8
- VEPZOLKTNZOTTQ-UHFFFAOYSA-N 1-butyl-n-(2,4,6-trimethylphenyl)pyrrolidine-2-carboxamide Chemical compound CCCCN1CCCC1C(=O)NC1=C(C)C=C(C)C=C1C VEPZOLKTNZOTTQ-UHFFFAOYSA-N 0.000 claims description 7
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 7
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 7
- UJRRDDHEMZLWFI-UHFFFAOYSA-N aminitrozole Chemical compound CC(=O)NC1=NC=C([N+]([O-])=O)S1 UJRRDDHEMZLWFI-UHFFFAOYSA-N 0.000 claims description 7
- 229950000695 aminitrozole Drugs 0.000 claims description 7
- 230000000844 anti-bacterial effect Effects 0.000 claims description 7
- 239000003814 drug Substances 0.000 claims description 7
- JPGDYIGSCHWQCC-UHFFFAOYSA-N emoxypine Chemical compound CCC1=NC(C)=CC=C1O JPGDYIGSCHWQCC-UHFFFAOYSA-N 0.000 claims description 7
- 210000000416 exudates and transudate Anatomy 0.000 claims description 7
- 235000010987 pectin Nutrition 0.000 claims description 7
- 239000001814 pectin Substances 0.000 claims description 7
- 229920001277 pectin Polymers 0.000 claims description 7
- 229920001817 Agar Polymers 0.000 claims description 6
- 108010010803 Gelatin Proteins 0.000 claims description 6
- 208000002847 Surgical Wound Diseases 0.000 claims description 6
- 235000010419 agar Nutrition 0.000 claims description 6
- 239000008273 gelatin Substances 0.000 claims description 6
- 229920000159 gelatin Polymers 0.000 claims description 6
- 235000019322 gelatine Nutrition 0.000 claims description 6
- 235000011852 gelatine desserts Nutrition 0.000 claims description 6
- 229960004393 lidocaine hydrochloride Drugs 0.000 claims description 4
- YECIFGHRMFEPJK-UHFFFAOYSA-N lidocaine hydrochloride monohydrate Chemical group O.[Cl-].CC[NH+](CC)CC(=O)NC1=C(C)C=CC=C1C YECIFGHRMFEPJK-UHFFFAOYSA-N 0.000 claims description 4
- 239000004599 antimicrobial Substances 0.000 claims 14
- 239000003193 general anesthetic agent Substances 0.000 claims 14
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 4
- 239000008272 agar Substances 0.000 claims 4
- 229940023476 agar Drugs 0.000 claims 4
- 229940072056 alginate Drugs 0.000 claims 4
- 235000010443 alginic acid Nutrition 0.000 claims 4
- 229920000615 alginic acid Polymers 0.000 claims 4
- 239000000679 carrageenan Substances 0.000 claims 4
- 235000010418 carrageenan Nutrition 0.000 claims 4
- 229920001525 carrageenan Polymers 0.000 claims 4
- 229940113118 carrageenan Drugs 0.000 claims 4
- KOOGJYYOMPUGCW-UHFFFAOYSA-N diethyl-[2-oxo-2-(2,4,6-trimethylanilino)ethyl]azanium;chloride Chemical compound [Cl-].CC[NH+](CC)CC(=O)NC1=C(C)C=C(C)C=C1C KOOGJYYOMPUGCW-UHFFFAOYSA-N 0.000 claims 4
- 229940014259 gelatin Drugs 0.000 claims 4
- 229910001629 magnesium chloride Inorganic materials 0.000 claims 4
- 235000011147 magnesium chloride Nutrition 0.000 claims 4
- 229960000292 pectin Drugs 0.000 claims 4
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 4
- 239000001913 cellulose Substances 0.000 claims 3
- 229920002678 cellulose Polymers 0.000 claims 3
- 235000010980 cellulose Nutrition 0.000 claims 3
- 238000011861 anti-inflammatory therapy Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000036407 pain Effects 0.000 abstract description 4
- 206010030113 Oedema Diseases 0.000 abstract description 3
- 238000004140 cleaning Methods 0.000 abstract description 3
- 230000008595 infiltration Effects 0.000 abstract description 3
- 238000001764 infiltration Methods 0.000 abstract description 3
- 208000011580 syndromic disease Diseases 0.000 abstract description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 2
- 230000002421 anti-septic effect Effects 0.000 description 11
- 230000003444 anaesthetic effect Effects 0.000 description 9
- 238000001356 surgical procedure Methods 0.000 description 8
- 230000035876 healing Effects 0.000 description 7
- 239000011159 matrix material Substances 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 239000000243 solution Substances 0.000 description 6
- 239000000654 additive Substances 0.000 description 5
- 230000003110 anti-inflammatory effect Effects 0.000 description 5
- 238000001266 bandaging Methods 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 150000003839 salts Chemical class 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 230000029663 wound healing Effects 0.000 description 5
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 4
- 229920006037 cross link polymer Polymers 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 235000010413 sodium alginate Nutrition 0.000 description 4
- 239000000661 sodium alginate Substances 0.000 description 4
- 229940005550 sodium alginate Drugs 0.000 description 4
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000011049 filling Methods 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 229960004194 lidocaine Drugs 0.000 description 3
- 230000001172 regenerating effect Effects 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- GOZBHBFUQHMKQB-UHFFFAOYSA-N trimecaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=C(C)C=C1C GOZBHBFUQHMKQB-UHFFFAOYSA-N 0.000 description 3
- 229950002569 trimecaine Drugs 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 208000012313 wound discharge Diseases 0.000 description 3
- 241000206672 Gelidium Species 0.000 description 2
- 206010031252 Osteomyelitis Diseases 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 239000003463 adsorbent Substances 0.000 description 2
- 229940064004 antiseptic throat preparations Drugs 0.000 description 2
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 208000028659 discharge Diseases 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000008733 trauma Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010007882 Cellulitis Diseases 0.000 description 1
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010016228 Fasciitis Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 229940030225 antihemorrhagics Drugs 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- QWNBTPQVFKSTLC-UHFFFAOYSA-N bis(ethenyl) pentanedioate Chemical compound C=COC(=O)CCCC(=O)OC=C QWNBTPQVFKSTLC-UHFFFAOYSA-N 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- -1 compounds sodium chloride Chemical class 0.000 description 1
- 238000007596 consolidation process Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940088679 drug related substance Drugs 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- KOWWOODYPWDWOJ-LVBPXUMQSA-N elatine Chemical compound C([C@]12CN(C3[C@@]45OCO[C@]44[C@H]6[C@@H](OC)[C@@H]([C@H](C4)OC)C[C@H]6[C@@]3([C@@H]1[C@@H]5OC)[C@@H](OC)CC2)CC)OC(=O)C1=CC=CC=C1N1C(=O)CC(C)C1=O KOWWOODYPWDWOJ-LVBPXUMQSA-N 0.000 description 1
- 239000002158 endotoxin Substances 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 239000000819 hypertonic solution Substances 0.000 description 1
- 229940021223 hypertonic solution Drugs 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 239000004531 microgranule Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000002643 mouth floor Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2003123513/15A RU2245723C1 (ru) | 2003-07-24 | 2003-07-24 | Средство и способ лечения гнойно-воспалительных заболеваний мягких тканей |
| RU2003123513 | 2003-07-24 | ||
| PCT/IB2004/002358 WO2005009448A1 (en) | 2003-07-24 | 2004-07-22 | Treatment of lesions of the soft tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2533707A1 true CA2533707A1 (en) | 2005-02-03 |
Family
ID=34102084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002533707A Abandoned CA2533707A1 (en) | 2003-07-24 | 2004-07-22 | Treatment of lesions of the soft tissues |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060120993A1 (https=) |
| EP (1) | EP1648419A1 (https=) |
| JP (1) | JP4729488B2 (https=) |
| AU (1) | AU2004258736A1 (https=) |
| CA (1) | CA2533707A1 (https=) |
| RU (1) | RU2245723C1 (https=) |
| WO (1) | WO2005009448A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006112690A1 (en) * | 2005-04-22 | 2006-10-26 | R & H Minerals B.V. | Mineral salt gel compositions |
| ES2399138T3 (es) * | 2006-03-16 | 2013-03-26 | Stellaris Pharmaceuticals Aps | Tratamiento local con factor VII |
| EP1982694B1 (en) * | 2007-04-20 | 2015-08-19 | D.M.G. Italia Srl | Anti-oedema composition |
| CA2727432C (en) * | 2008-06-12 | 2016-10-11 | Medtronic Xomed, Inc. | Method for treating chronic wounds with an extracellular polymeric substance solvating system |
| RU2646462C1 (ru) * | 2017-04-11 | 2018-03-05 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Средство для лечения гнойно-воспалительных процессов мягких тканей и слизистых оболочек |
| RU2641095C1 (ru) * | 2017-04-11 | 2018-01-15 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Средство для лечения гнойно-воспалительных процессов мягких тканей и слизистых оболочек |
| RU2697669C1 (ru) * | 2019-01-17 | 2019-08-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Курская государственная сельскохозяйственная академия имени И.И. Иванова" | Ранозаживляющий гель с липосомами и способ его получения |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3146841A1 (de) * | 1981-11-26 | 1983-06-01 | Beiersdorf Ag, 2000 Hamburg | "neue wundbehandlungsmittel" |
| JPS63160661A (ja) * | 1986-12-24 | 1988-07-04 | テルモ株式会社 | 外用組成物 |
| JPH05117158A (ja) * | 1991-10-22 | 1993-05-14 | Sasaki Kagaku Yakuhin Kk | 皮膚外用剤組成物 |
| RU2031661C1 (ru) * | 1993-07-16 | 1995-03-27 | Научно-производственное предприятие "Экомедсервис" | Средство для лечения ран и оказания первой медицинской помощи |
| JP3583166B2 (ja) * | 1994-06-27 | 2004-10-27 | 興和株式会社 | 損傷皮膚修復用粉末製剤 |
| RU2115436C1 (ru) * | 1995-04-13 | 1998-07-20 | Институт хирургии им.А.В.Вишневского РАМН | Средство для лечения ран |
| RU2120306C1 (ru) * | 1995-05-06 | 1998-10-20 | Государственный научный центр "Карповский институт" | Средство для лечения ран и ожогов |
| RU2071788C1 (ru) * | 1995-08-21 | 1997-01-20 | Акционерное общество закрытого типа Многопрофильный комплекс "Универсал" | Средство для лечения ран |
| JPH09110702A (ja) * | 1995-10-17 | 1997-04-28 | Showa Denko Kk | 海洋深層水含有ゲル製剤 |
| JPH1017479A (ja) * | 1996-07-01 | 1998-01-20 | Showa Denko Kk | 塩含有外用剤 |
| RU2161493C1 (ru) * | 1999-07-07 | 2001-01-10 | Николаев Максим Евгеньевич | Способ закрытия и лечения раневых поверхностей и покрытие для его осуществления |
| CA2323382C (en) * | 2000-10-17 | 2004-04-13 | Pharma Mag Inc. | Wound dressing |
-
2003
- 2003-07-24 RU RU2003123513/15A patent/RU2245723C1/ru not_active IP Right Cessation
-
2004
- 2004-07-22 EP EP04744018A patent/EP1648419A1/en not_active Withdrawn
- 2004-07-22 CA CA002533707A patent/CA2533707A1/en not_active Abandoned
- 2004-07-22 WO PCT/IB2004/002358 patent/WO2005009448A1/en not_active Ceased
- 2004-07-22 JP JP2006520930A patent/JP4729488B2/ja not_active Expired - Fee Related
- 2004-07-22 AU AU2004258736A patent/AU2004258736A1/en not_active Abandoned
-
2006
- 2006-01-23 US US11/337,433 patent/US20060120993A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2003123513A (ru) | 2005-01-27 |
| WO2005009448A8 (en) | 2005-05-06 |
| AU2004258736A1 (en) | 2005-02-03 |
| WO2005009448A1 (en) | 2005-02-03 |
| EP1648419A1 (en) | 2006-04-26 |
| JP4729488B2 (ja) | 2011-07-20 |
| US20060120993A1 (en) | 2006-06-08 |
| RU2245723C1 (ru) | 2005-02-10 |
| JP2006528622A (ja) | 2006-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |