CA2533345A1 - Piperidyl-quinazoline derivatives as tyrosine kinase inhibitors - Google Patents
Piperidyl-quinazoline derivatives as tyrosine kinase inhibitors Download PDFInfo
- Publication number
- CA2533345A1 CA2533345A1 CA002533345A CA2533345A CA2533345A1 CA 2533345 A1 CA2533345 A1 CA 2533345A1 CA 002533345 A CA002533345 A CA 002533345A CA 2533345 A CA2533345 A CA 2533345A CA 2533345 A1 CA2533345 A1 CA 2533345A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutically acceptable
- formula
- quinazoline derivative
- acceptable salt
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 239000005483 tyrosine kinase inhibitor Substances 0.000 title description 5
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Classifications
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- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ceramic Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Inorganic Chemistry (AREA)
- Structural Engineering (AREA)
- Urology & Nephrology (AREA)
- Materials Engineering (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0317665.8A GB0317665D0 (en) | 2003-07-29 | 2003-07-29 | Qinazoline derivatives |
| GB0317665.8 | 2003-07-29 | ||
| US10/857,342 US7148230B2 (en) | 2003-07-29 | 2004-06-01 | Quinazoline derivatives |
| US10/857,342 | 2004-06-01 | ||
| PCT/GB2004/003259 WO2005012290A1 (en) | 2003-07-29 | 2004-07-27 | Piperidyl-quinazoline derivatives as tyrosine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2533345A1 true CA2533345A1 (en) | 2005-02-10 |
Family
ID=34117645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002533345A Abandoned CA2533345A1 (en) | 2003-07-29 | 2004-07-27 | Piperidyl-quinazoline derivatives as tyrosine kinase inhibitors |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20070099943A1 (https=) |
| EP (1) | EP1660479A1 (https=) |
| JP (1) | JP2007500177A (https=) |
| KR (1) | KR20060054388A (https=) |
| AU (1) | AU2004261477A1 (https=) |
| BR (1) | BRPI0413066A (https=) |
| CA (1) | CA2533345A1 (https=) |
| MX (1) | MXPA06001079A (https=) |
| NO (1) | NO20060415L (https=) |
| UY (1) | UY28441A1 (https=) |
| WO (1) | WO2005012290A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050043336A1 (en) * | 2001-11-03 | 2005-02-24 | Hennequin Laurent Francois Andre | Quinazoline derivatives as antitumor agents |
| GB0126433D0 (en) * | 2001-11-03 | 2002-01-02 | Astrazeneca Ab | Compounds |
| TWI324597B (en) * | 2002-03-28 | 2010-05-11 | Astrazeneca Ab | Quinazoline derivatives |
| US6924285B2 (en) | 2002-03-30 | 2005-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
| GB0309009D0 (en) * | 2003-04-22 | 2003-05-28 | Astrazeneca Ab | Quinazoline derivatives |
| GB0309850D0 (en) * | 2003-04-30 | 2003-06-04 | Astrazeneca Ab | Quinazoline derivatives |
| EP1664028A1 (en) * | 2003-09-16 | 2006-06-07 | AstraZeneca AB | Quinazoline derivatives as tyrosine kinase inhibitors |
| ATE395346T1 (de) | 2003-09-16 | 2008-05-15 | Astrazeneca Ab | Chinazolinderivate als tyrosinkinaseinhibitoren |
| GB0321648D0 (en) * | 2003-09-16 | 2003-10-15 | Astrazeneca Ab | Quinazoline derivatives |
| AU2004272346A1 (en) * | 2003-09-16 | 2005-03-24 | Astrazeneca Ab | Quinazoline derivatives |
| EP1664030A1 (en) * | 2003-09-16 | 2006-06-07 | AstraZeneca AB | Quinazoline derivatives |
| CN1882570B (zh) * | 2003-09-19 | 2010-12-08 | 阿斯利康(瑞典)有限公司 | 喹唑啉衍生物 |
| ES2279441T3 (es) * | 2003-09-19 | 2007-08-16 | Astrazeneca Ab | Derivados de quinazolina. |
| GB0322409D0 (en) * | 2003-09-25 | 2003-10-29 | Astrazeneca Ab | Quinazoline derivatives |
| WO2005030757A1 (en) * | 2003-09-25 | 2005-04-07 | Astrazeneca Ab | Quinazoline derivatives |
| GB0326459D0 (en) | 2003-11-13 | 2003-12-17 | Astrazeneca Ab | Quinazoline derivatives |
| DE602005010824D1 (de) | 2004-02-03 | 2008-12-18 | Astrazeneca Ab | Chinazolinderivate |
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| EP2313397B1 (de) | 2008-08-08 | 2016-04-20 | Boehringer Ingelheim International GmbH | Cyclohexyloxy-substituierte heterocyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
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-
2004
- 2004-07-27 UY UY28441A patent/UY28441A1/es unknown
- 2004-07-27 JP JP2006521660A patent/JP2007500177A/ja active Pending
- 2004-07-27 WO PCT/GB2004/003259 patent/WO2005012290A1/en not_active Ceased
- 2004-07-27 CA CA002533345A patent/CA2533345A1/en not_active Abandoned
- 2004-07-27 KR KR1020067002070A patent/KR20060054388A/ko not_active Withdrawn
- 2004-07-27 AU AU2004261477A patent/AU2004261477A1/en not_active Abandoned
- 2004-07-27 BR BRPI0413066-9A patent/BRPI0413066A/pt not_active Application Discontinuation
- 2004-07-27 MX MXPA06001079A patent/MXPA06001079A/es unknown
- 2004-07-27 EP EP04743586A patent/EP1660479A1/en not_active Withdrawn
-
2006
- 2006-01-25 NO NO20060415A patent/NO20060415L/no not_active Application Discontinuation
- 2006-12-11 US US11/636,549 patent/US20070099943A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0413066A (pt) | 2006-10-17 |
| UY28441A1 (es) | 2005-02-28 |
| JP2007500177A (ja) | 2007-01-11 |
| US20070099943A1 (en) | 2007-05-03 |
| WO2005012290A1 (en) | 2005-02-10 |
| NO20060415L (no) | 2006-02-07 |
| KR20060054388A (ko) | 2006-05-22 |
| MXPA06001079A (es) | 2006-04-11 |
| EP1660479A1 (en) | 2006-05-31 |
| AU2004261477A1 (en) | 2005-02-10 |
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Legal Events
| Date | Code | Title | Description |
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| FZDE | Discontinued |