CA2506068C - Pharmaceutical composition containing sfcyr iib or sfcyr iii - Google Patents
Pharmaceutical composition containing sfcyr iib or sfcyr iii Download PDFInfo
- Publication number
- CA2506068C CA2506068C CA2506068A CA2506068A CA2506068C CA 2506068 C CA2506068 C CA 2506068C CA 2506068 A CA2506068 A CA 2506068A CA 2506068 A CA2506068 A CA 2506068A CA 2506068 C CA2506068 C CA 2506068C
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- Prior art keywords
- ser
- pharmaceutical composition
- leu
- thr
- val
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 22
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 17
- 201000010099 disease Diseases 0.000 claims abstract description 15
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- 206010039073 rheumatoid arthritis Diseases 0.000 claims abstract description 10
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- 210000000822 natural killer cell Anatomy 0.000 claims description 10
- 208000023275 Autoimmune disease Diseases 0.000 claims description 6
- 238000002347 injection Methods 0.000 claims description 6
- 239000007924 injection Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 239000000243 solution Substances 0.000 claims description 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000009465 prokaryotic expression Effects 0.000 claims 1
- 230000008105 immune reaction Effects 0.000 abstract description 7
- 102000009109 Fc receptors Human genes 0.000 description 21
- 108010087819 Fc receptors Proteins 0.000 description 21
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- 108020003175 receptors Proteins 0.000 description 17
- 241000699670 Mus sp. Species 0.000 description 15
- 238000011282 treatment Methods 0.000 description 14
- 238000000034 method Methods 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
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- JBVSSSZFNTXJDX-YTLHQDLWSA-N Ala-Ala-Thr Chemical compound C[C@@H](O)[C@@H](C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)N JBVSSSZFNTXJDX-YTLHQDLWSA-N 0.000 description 2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10157290A DE10157290A1 (de) | 2001-11-22 | 2001-11-22 | Pharmazeutische Zusammensetzung enthaltend sFcRgamma IIb oder sFcRgamma III |
| DE10157290.5 | 2001-11-22 | ||
| PCT/EP2002/013080 WO2003043648A2 (de) | 2001-11-22 | 2002-11-21 | Sfcyr iib oder sfcyr iii für die behandlung von autoimmunkrankheiten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2506068A1 CA2506068A1 (en) | 2003-05-30 |
| CA2506068C true CA2506068C (en) | 2011-09-20 |
Family
ID=7706571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2506068A Expired - Lifetime CA2506068C (en) | 2001-11-22 | 2002-11-21 | Pharmaceutical composition containing sfcyr iib or sfcyr iii |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20050002924A1 (enExample) |
| EP (1) | EP1446139B1 (enExample) |
| JP (1) | JP5414959B2 (enExample) |
| AT (1) | ATE409045T1 (enExample) |
| AU (1) | AU2002366200A1 (enExample) |
| CA (1) | CA2506068C (enExample) |
| CO (1) | CO5590936A2 (enExample) |
| DE (2) | DE10157290A1 (enExample) |
| ES (1) | ES2309238T3 (enExample) |
| WO (1) | WO2003043648A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1709073B1 (en) | 2003-11-26 | 2011-08-10 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | SUBSTANCE BINDING HUMAN IgG Fc RECEPTOR IIb (FcgammaRIIb) |
| US10669324B2 (en) | 2012-10-30 | 2020-06-02 | Suppremol Gmbh | Vector encoding an Fc gamma receptor IIB protein and composition of the encoded protein |
| EP2914623B1 (en) | 2012-10-30 | 2016-12-28 | SuppreMol GmbH | A pharmaceutical composition for use in treating or preventing either one or both of an inflammatory disease and an autoimmune disease |
| US10028998B2 (en) * | 2012-10-30 | 2018-07-24 | Suppremol Gmbh | Method for treating an inflammatory disease and/or an autoimmune disease with a soluble FcγRIIb |
| AU2012244302B2 (en) * | 2012-10-31 | 2014-08-21 | Suppremol Gmbh | A method for treating or preventing either one or both of an inflammatory disease and an autoimmune disease |
| EP2796144A1 (en) | 2013-04-26 | 2014-10-29 | SuppreMol GmbH | Highly concentrated Formulations of soluble Fc receptors |
| EP2833139A1 (en) | 2013-08-01 | 2015-02-04 | SuppreMol GmbH | In vitro method for determining the stability of compositions comprising soluble Fc gamma receptor(s) |
| EP2837637A1 (en) | 2013-08-16 | 2015-02-18 | SuppreMol GmbH | Novel anti-FcyRIIB IgG-type antibody |
| JP6893223B2 (ja) * | 2013-10-16 | 2021-06-23 | ズプレモル ゲーエムベーハー | 医薬品組成物およびキット |
| KR102138219B1 (ko) | 2013-10-16 | 2020-07-28 | 수프레몰 게엠베하 | 자가면역 수포성 질환의 치료를 위한 가용성 Fc 감마 수용체 |
| JP2018050616A (ja) | 2016-09-23 | 2018-04-05 | 東ソー株式会社 | 改良型組換えＦｃγＲＩＩ |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999040117A1 (en) * | 1998-02-06 | 1999-08-12 | Ilexus Pty. Limited | THREE-DIMENSIONAL STRUCTURES AND MODELS OF Fc RECEPTORS AND USES THEREOF |
| EP1006183A1 (en) * | 1998-12-03 | 2000-06-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Recombinant soluble Fc receptors |
| EP1201681A1 (en) * | 2000-10-30 | 2002-05-02 | Millennium Pharmaceuticals, Inc. | "Fail" molecules and uses thereof |
-
2001
- 2001-11-22 DE DE10157290A patent/DE10157290A1/de not_active Withdrawn
-
2002
- 2002-11-21 JP JP2003545329A patent/JP5414959B2/ja not_active Expired - Lifetime
- 2002-11-21 AU AU2002366200A patent/AU2002366200A1/en not_active Abandoned
- 2002-11-21 CA CA2506068A patent/CA2506068C/en not_active Expired - Lifetime
- 2002-11-21 EP EP02803402A patent/EP1446139B1/de not_active Expired - Lifetime
- 2002-11-21 ES ES02803402T patent/ES2309238T3/es not_active Expired - Lifetime
- 2002-11-21 AT AT02803402T patent/ATE409045T1/de active
- 2002-11-21 WO PCT/EP2002/013080 patent/WO2003043648A2/de not_active Ceased
- 2002-11-21 DE DE50212814T patent/DE50212814D1/de not_active Expired - Lifetime
-
2004
- 2004-05-24 US US10/851,655 patent/US20050002924A1/en not_active Abandoned
- 2004-06-18 CO CO04057552A patent/CO5590936A2/es not_active Application Discontinuation
-
2008
- 2008-01-09 US US11/971,438 patent/US20080214459A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CO5590936A2 (es) | 2005-12-30 |
| JP5414959B2 (ja) | 2014-02-12 |
| ES2309238T3 (es) | 2008-12-16 |
| AU2002366200A1 (en) | 2003-06-10 |
| WO2003043648A2 (de) | 2003-05-30 |
| DE10157290A1 (de) | 2003-06-05 |
| AU2002366200A8 (en) | 2003-06-10 |
| EP1446139A2 (de) | 2004-08-18 |
| US20050002924A1 (en) | 2005-01-06 |
| JP2005515981A (ja) | 2005-06-02 |
| WO2003043648A3 (de) | 2004-01-08 |
| DE50212814D1 (de) | 2008-11-06 |
| CA2506068A1 (en) | 2003-05-30 |
| ATE409045T1 (de) | 2008-10-15 |
| US20080214459A1 (en) | 2008-09-04 |
| EP1446139B1 (de) | 2008-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20221121 |