CA2505478A1 - Antioxidant pharmaceutical compound, method for producing polypeptide and method of cure - Google Patents
Antioxidant pharmaceutical compound, method for producing polypeptide and method of cure Download PDFInfo
- Publication number
- CA2505478A1 CA2505478A1 CA002505478A CA2505478A CA2505478A1 CA 2505478 A1 CA2505478 A1 CA 2505478A1 CA 002505478 A CA002505478 A CA 002505478A CA 2505478 A CA2505478 A CA 2505478A CA 2505478 A1 CA2505478 A1 CA 2505478A1
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- Prior art keywords
- peroxiredoxin
- prx
- fragment
- cells
- antioxidant
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Classifications
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- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01015—Peroxiredoxin (1.11.1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
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- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2002129774 | 2002-11-10 | ||
| RU2002129774/15A RU2280448C2 (ru) | 2002-11-10 | 2002-11-10 | Композиция с антиоксидантными свойствами и способ лечения болезней млекопитающих |
| RU2003123534 | 2003-07-29 | ||
| RU2003123534/13A RU2250262C1 (ru) | 2003-07-29 | 2003-07-29 | РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pET23-a(+)PrxVIhumΔ178, КОДИРУЮЩАЯ N-КОНЦЕВОЙ ФРАГМЕНТ ПЕРОКСИРЕДОКСИНА VI ЧЕЛОВЕКА, И ШТАММ E.coli BL21/DE3/pET23-a(+)/PrxVIhumΔ178 - ПРОДУЦЕНТ N-КОНЦЕВОГО ФРАГМЕНТА ПЕРОКСИРЕДОКСИНА VI ЧЕЛОВЕКА |
| PCT/RU2003/000473 WO2004043485A1 (en) | 2002-11-10 | 2003-11-05 | Antioxidant pharmaceutical compound, method for producing polypeptide and method of cure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2505478A1 true CA2505478A1 (en) | 2004-05-27 |
Family
ID=32314175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002505478A Abandoned CA2505478A1 (en) | 2002-11-10 | 2003-11-05 | Antioxidant pharmaceutical compound, method for producing polypeptide and method of cure |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8003345B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1566182A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2006505290A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2505478A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004043485A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010101301A1 (en) * | 2009-03-05 | 2010-09-10 | National University Corporation University Of Fukui | Prophylaxis and treatment of macular degeneration and retinopathy using a prdx protein |
| CN102573881A (zh) * | 2009-03-20 | 2012-07-11 | 通用医疗公司以马萨诸塞州通用医疗公司名义经营 | 预防和治疗烧伤损伤和继发性并发症的方法 |
| US8859235B2 (en) * | 2009-08-14 | 2014-10-14 | Basf Se | Methods in cell cultures, and related inventions, employing certain additives |
| JP5684397B2 (ja) * | 2010-10-25 | 2015-03-11 | コリア アトミック エナジー リサーチ インスティテュート | 放射線の照射を用いたペルオキシレドキシンのシャペロン活性調節方法 |
| CN102485272A (zh) * | 2010-12-06 | 2012-06-06 | 李建远 | 重组人Prx-6蛋白在治疗烧烫伤方面的用途 |
| CN102793911B (zh) * | 2011-05-24 | 2015-12-16 | 李建远 | 重组人Prx-6蛋白在治疗角膜损伤方面的用途 |
| WO2012075911A1 (zh) * | 2010-12-06 | 2012-06-14 | Li Jianyuan | 重组人prx-6蛋白在治疗烧烫伤和/或角膜损伤中的用途 |
| CN103417961B (zh) * | 2012-05-23 | 2018-02-09 | 烟台聚杰生物工程有限公司 | Prdx2和/或prdx6的新用途 |
| CN105211054B (zh) * | 2015-11-10 | 2017-05-24 | 刘娟 | 一种含重组人prdx4蛋白的人精液冷冻保护剂 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9612214D0 (en) * | 1996-06-11 | 1996-08-14 | Mallinckrodt Veterinary Inc | Vaccine |
| CA2285631A1 (en) * | 1997-04-02 | 1998-10-08 | The Jackson Laboratory | Antioxidant protein 2, gene and methods of use therefor |
| BE1011331A6 (fr) * | 1997-08-20 | 1999-07-06 | Univ Catholique De Louvain Hal | Polypeptide associe au peroxysome, sequence nucleotidique encodant ledit polypeptide et leur utilisation dans le diagnostic et/ou le traitement de maladies ou de lesions pulmonaires. |
| AR042572A1 (es) * | 1999-04-02 | 2005-06-29 | Sod Conseils Rech Applic | Derivados de acido lipoico, procedimiento para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y utilizacion de dichos derivados para la preparacion de los referidos medicamentos |
| FR2798672B1 (fr) | 1999-09-17 | 2003-10-31 | Commissariat Energie Atomique | Formes acides des peroxyredoxines et leur utilisation comme moyen de diagnostic |
| US20030186839A1 (en) * | 2000-08-28 | 2003-10-02 | Akira Awaya | Medicinal compositions |
| US20020168353A1 (en) * | 2001-03-23 | 2002-11-14 | Lynn Ralf Geiben | Peroxiredoxin drugs for treatment of HIV-1 infection and methods of use thereof |
| WO2002061063A1 (en) * | 2001-01-30 | 2002-08-08 | Universite Catholique De Louvain | Crystal structure of peroxiredoxin 5 and its use for design of structural homologues |
| EP1394182A1 (en) | 2002-07-08 | 2004-03-03 | Europroteome AG | Agents and methods for diagnosis and therapy of cancer and cancer risk assessment |
| RU2250262C1 (ru) | 2003-07-29 | 2005-04-20 | Институт биоорганической химии им. академиков М.М.Шемякина и Ю.А.Овчинникова РАН | РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pET23-a(+)PrxVIhumΔ178, КОДИРУЮЩАЯ N-КОНЦЕВОЙ ФРАГМЕНТ ПЕРОКСИРЕДОКСИНА VI ЧЕЛОВЕКА, И ШТАММ E.coli BL21/DE3/pET23-a(+)/PrxVIhumΔ178 - ПРОДУЦЕНТ N-КОНЦЕВОГО ФРАГМЕНТА ПЕРОКСИРЕДОКСИНА VI ЧЕЛОВЕКА |
| RU2280448C2 (ru) | 2002-11-10 | 2006-07-27 | Институт биофизики клетки РАН | Композиция с антиоксидантными свойствами и способ лечения болезней млекопитающих |
| JP5019878B2 (ja) * | 2003-09-20 | 2012-09-05 | エレクトロフォレティックス リミテッド | 脳障害関連疾患の診断のためのマーカーの検出に関する方法 |
| KR100569165B1 (ko) | 2003-11-14 | 2006-04-07 | (주)아비코아생명공학연구소 | 닭 퍼옥시레독신 1 단백질 및 그를 코딩하는 핵산분자 |
| KR100605308B1 (ko) | 2003-12-01 | 2006-07-26 | 전남대학교산학협력단 | ＰｒｘⅡ 단백질의 혈관 내피세포 탐지용 마아커로서의 용도 |
| WO2005123944A1 (en) * | 2004-06-18 | 2005-12-29 | Roche Diagnostics Gmbh | Use of protein pdx1 as a marker for breast cancer |
| KR100953326B1 (ko) | 2004-08-31 | 2010-04-20 | 이화여자대학교 산학협력단 | 페록시레독신의 활성검출 키트 |
| KR100610774B1 (ko) * | 2005-02-03 | 2006-08-28 | 이화여자대학교 산학협력단 | 퍼록시레독신 2 단백질을 유효성분으로 함유하는 혈관재협착 예방 및 치료용 약학조성물, 퍼록시레독신 2유전자 또는 그로부터 발현되는 단백질을 포함하는 혈관재협착 치료제 스크리닝용 조성물 및 이를 이용하는 혈관재협착 치료제 스크리닝 방법 |
| WO2007140976A2 (en) | 2006-06-06 | 2007-12-13 | F. Hoffmann-La Roche Ag | Enzymes as biomarker for alzheimer's disease |
| US20100297673A1 (en) | 2006-09-20 | 2010-11-25 | Reddy Us Therapeutics | Methods and compositions for upregulation of peroxiredoxin activity |
| JP2008275413A (ja) | 2007-04-27 | 2008-11-13 | Osaka Industrial Promotion Organization | 扁平上皮癌の診断用キット及び判定方法 |
-
2003
- 2003-11-05 CA CA002505478A patent/CA2505478A1/en not_active Abandoned
- 2003-11-05 US US10/534,238 patent/US8003345B2/en not_active Expired - Fee Related
- 2003-11-05 EP EP03774414A patent/EP1566182A4/en not_active Ceased
- 2003-11-05 WO PCT/RU2003/000473 patent/WO2004043485A1/ru not_active Ceased
- 2003-11-05 JP JP2005506685A patent/JP2006505290A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1566182A4 (en) | 2009-08-19 |
| WO2004043485A1 (en) | 2004-05-27 |
| US8003345B2 (en) | 2011-08-23 |
| JP2006505290A (ja) | 2006-02-16 |
| EP1566182A1 (en) | 2005-08-24 |
| US20060147440A1 (en) | 2006-07-06 |
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