CA2501028C - Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel - Google Patents

Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel Download PDF

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Publication number
CA2501028C
CA2501028C CA2501028A CA2501028A CA2501028C CA 2501028 C CA2501028 C CA 2501028C CA 2501028 A CA2501028 A CA 2501028A CA 2501028 A CA2501028 A CA 2501028A CA 2501028 C CA2501028 C CA 2501028C
Authority
CA
Canada
Prior art keywords
pipetting needle
needle
level sensor
signal
vibration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2501028A
Other languages
English (en)
French (fr)
Other versions
CA2501028A1 (en
Inventor
Markus Brunner
Juerg Dual
Olivier Elsenhans
Frank May
Vuk Siljegovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2501028A1 publication Critical patent/CA2501028A1/en
Application granted granted Critical
Publication of CA2501028C publication Critical patent/CA2501028C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/22—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
    • G01F23/28—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring the variations of parameters of electromagnetic or acoustic waves applied directly to the liquid or fluent solid material
    • G01F23/296—Acoustic waves
    • G01F23/2965—Measuring attenuation of transmitted waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/22—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
    • G01F23/28—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring the variations of parameters of electromagnetic or acoustic waves applied directly to the liquid or fluent solid material
    • G01F23/296—Acoustic waves
    • G01F23/2966—Acoustic waves making use of acoustical resonance or standing waves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Thermal Sciences (AREA)
  • Electromagnetism (AREA)
  • Acoustics & Sound (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Measurement Of Levels Of Liquids Or Fluent Solid Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CA2501028A 2004-05-14 2005-03-17 Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel Expired - Fee Related CA2501028C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04076435A EP1596169B1 (en) 2004-05-14 2004-05-14 Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel
EP04076435.9 2004-05-14

Publications (2)

Publication Number Publication Date
CA2501028A1 CA2501028A1 (en) 2005-11-14
CA2501028C true CA2501028C (en) 2010-02-09

Family

ID=34928220

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2501028A Expired - Fee Related CA2501028C (en) 2004-05-14 2005-03-17 Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel

Country Status (4)

Country Link
US (1) US7416706B2 (enExample)
EP (1) EP1596169B1 (enExample)
JP (1) JP4754873B2 (enExample)
CA (1) CA2501028C (enExample)

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DE102006007199A1 (de) * 2006-02-15 2007-08-16 Vega Grieshaber Kg Vibrationsgrenzschalteranordnung bzw. Verfahren zum Korrigieren eines Vibrationsgrenzschalter-Schaltpunktes
US7870797B2 (en) * 2006-04-03 2011-01-18 Artel, Inc. Apparatus and method for aspirating and dispensing liquid
US8268261B2 (en) * 2006-11-22 2012-09-18 Altair Corporation Pipette core member, pipette, and pipette device
US8703492B2 (en) 2007-04-06 2014-04-22 Qiagen Gaithersburg, Inc. Open platform hybrid manual-automated sample processing system
US7985375B2 (en) * 2007-04-06 2011-07-26 Qiagen Gaithersburg, Inc. Sample preparation system and method for processing clinical specimens
ES2645096T3 (es) * 2007-04-18 2017-12-04 Becton, Dickinson And Company Método y aparato para determinar el volumen de dispensación
DE102008009626A1 (de) 2008-02-18 2009-08-27 Advalytix Ag Verfahren zur Zustandsüberprüfung einer Pipette, Pipettierverfahren, Pipettiervorrichtung und Saugrohr für eine Pipettiervorrichtung
US8776621B2 (en) * 2009-03-06 2014-07-15 Dionex Corporation Fluid sample delivery system and method
US9953141B2 (en) 2009-11-18 2018-04-24 Becton, Dickinson And Company Laboratory central control unit method and system
DE102010001229A1 (de) * 2010-01-26 2011-07-28 Hamilton Bonaduz Ag Verfahren und Vorrichtung zur Bestimmung eines flüssigkeitsspezifischen oder vom Benetzungszustand einer Pipettierspitze abhängigen Parameters durch Schwingungsanregung
JP5277214B2 (ja) * 2010-07-27 2013-08-28 株式会社日立ハイテクノロジーズ 自動分析装置
EP2665557B1 (en) * 2011-01-21 2020-01-01 Biodot, Inc. Piezoelectric dispenser with a longitudinal transducer and replaceable capillary tube
JP5850625B2 (ja) * 2011-03-02 2016-02-03 シスメックス株式会社 分析装置及び位置確認方法
DE102011006581A1 (de) 2011-03-31 2012-10-04 Hamilton Bonaduz Ag Zustandsüberwachung einer Pipettenspitze mit von innen angekoppelten piezoelektrischen Elementen
CN103604484B (zh) * 2013-10-29 2017-02-22 北京利德曼生化股份有限公司 用于全自动生化分析仪反应盘的液位探测装置
WO2015092844A1 (ja) * 2013-12-16 2015-06-25 株式会社島津製作所 液採取装置及びその液採取装置を備えた自動分析装置
JP6280777B2 (ja) * 2014-03-24 2018-02-14 シスメックス株式会社 分析装置、及び分析装置における液面検出方法
JP6391338B2 (ja) * 2014-07-18 2018-09-19 株式会社日立ハイテクノロジーズ 自動分析装置
WO2016049378A1 (en) * 2014-09-24 2016-03-31 Duke University Disposable pipette tip and methods of use
EP3096148B1 (de) * 2015-05-20 2024-01-03 Siemens Healthcare Diagnostics Products GmbH Pipettiervorrichtung
ES2699894T3 (es) * 2015-07-03 2019-02-13 Siemens Healthcare Diagnostics Products Gmbh Procedimiento para la detección de contacto de una aguja de pipeteo
TWI600884B (zh) * 2016-05-19 2017-10-01 博泰科技有限公司 具水量測量功能之杯具
WO2019005744A1 (en) * 2017-06-26 2019-01-03 Luedemann Hans Christian LIQUID TRANSFER DEVICE WITH INTEGRATED DISTANCE SENSOR AND NON-CONTACT LIQUID FILLING HEIGHT, AND METHODS
CN109030096A (zh) * 2018-06-06 2018-12-18 迈克医疗电子有限公司 取液测试方法及装置
CN109030098A (zh) * 2018-06-06 2018-12-18 迈克医疗电子有限公司 取液测试方法及装置
CN109030095B (zh) * 2018-06-06 2021-08-31 迈克医疗电子有限公司 取液测试方法及装置
CN109030097B (zh) * 2018-06-06 2023-04-18 迈克医疗电子有限公司 取液测试方法及装置
WO2021086550A1 (en) * 2019-10-28 2021-05-06 Siemens Healthcare Diagnostics Inc. Vibrating pipette tips and methods of preventing pipette tip stiction
DE102019134200A1 (de) * 2019-12-12 2021-06-17 Hamilton Bonaduz Ag Pipettiereinheit mit kapazitiver Flüssigkeitsdetektion, Kombination einer solchen Pipettiereinheit und einer Pipettierspitze, und Verfahren zum kapazitiven Detektieren von Pipettierflüssigkeit
JP7353223B2 (ja) * 2020-03-10 2023-09-29 株式会社日立ハイテク 液面検知装置、及び自動分析装置

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US5750881A (en) * 1995-07-13 1998-05-12 Chiron Diagnostics Corporation Method and apparatus for aspirating and dispensing sample fluids
EP0913671A1 (de) * 1997-10-29 1999-05-06 Roche Diagnostics GmbH Verfahren und Vorrichtung zum Flüssigkeitstransfer mit einem Analysegerät
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AU2001245365B8 (en) * 2000-02-29 2005-11-03 Gen-Probe Incorporated Fluid dispense and liquid surface verification system and method
EP1207396A1 (fr) * 2000-10-20 2002-05-22 Seyonic SA Dispositif dispensateur de fluide
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US7097810B2 (en) * 2002-06-26 2006-08-29 The Public Health Research Institute Of The City Of New York, Inc. Delivery of metered amounts of liquid materials
US6874699B2 (en) * 2002-10-15 2005-04-05 Wisconsin Alumni Research Foundation Methods and apparata for precisely dispensing microvolumes of fluids
US7125727B2 (en) * 2003-01-29 2006-10-24 Protedyne Corporation Sample handling tool with piezoelectric actuator
US7396512B2 (en) * 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
US7258480B2 (en) * 2005-01-10 2007-08-21 Dade Behring Inc. Apparatus for mixing liquid samples using a two dimensional stirring pattern

Also Published As

Publication number Publication date
JP4754873B2 (ja) 2011-08-24
EP1596169A1 (en) 2005-11-16
US20060093525A1 (en) 2006-05-04
EP1596169B1 (en) 2012-05-30
CA2501028A1 (en) 2005-11-14
US7416706B2 (en) 2008-08-26
JP2005345466A (ja) 2005-12-15

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Effective date: 20230317