CA2485268A1 - Resorbable pharmaceutical formulation for the continuous release of thrombin - Google Patents

Resorbable pharmaceutical formulation for the continuous release of thrombin Download PDF

Info

Publication number
CA2485268A1
CA2485268A1 CA002485268A CA2485268A CA2485268A1 CA 2485268 A1 CA2485268 A1 CA 2485268A1 CA 002485268 A CA002485268 A CA 002485268A CA 2485268 A CA2485268 A CA 2485268A CA 2485268 A1 CA2485268 A1 CA 2485268A1
Authority
CA
Canada
Prior art keywords
resorbable
pharmaceutical formulation
thrombin
formulation according
collagen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002485268A
Other languages
English (en)
French (fr)
Inventor
Frank Gerhards
Rui-Miguel Pereira-Paz
Doris Klee
Hartwig Hoecker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Rheinisch Westlische Technische Hochschuke RWTH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rheinisch Westlische Technische Hochschuke RWTH filed Critical Rheinisch Westlische Technische Hochschuke RWTH
Publication of CA2485268A1 publication Critical patent/CA2485268A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002485268A 2002-05-08 2003-05-05 Resorbable pharmaceutical formulation for the continuous release of thrombin Abandoned CA2485268A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10220030.0 2002-05-08
DE10220030 2002-05-08
PCT/EP2003/004680 WO2003094983A1 (de) 2002-05-08 2003-05-05 Resorbierbare pharmazeutische formulierung zur kontinuierlichen thrombinfreisetzung

Publications (1)

Publication Number Publication Date
CA2485268A1 true CA2485268A1 (en) 2003-11-20

Family

ID=29413701

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002485268A Abandoned CA2485268A1 (en) 2002-05-08 2003-05-05 Resorbable pharmaceutical formulation for the continuous release of thrombin

Country Status (4)

Country Link
EP (1) EP1501558A1 (de)
AU (1) AU2003232257A1 (de)
CA (1) CA2485268A1 (de)
WO (1) WO2003094983A1 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104163779A (zh) * 2014-06-06 2014-11-26 浙江工业大学 一种管式连续化制备亚硫酸氢钠甲萘醌的方法
US9283187B2 (en) 2011-04-27 2016-03-15 Biom'up Hemostatic compositions
CN111053944A (zh) * 2019-11-28 2020-04-24 中国科学院大学温州研究院(温州生物材料与工程研究所) 一种载凝血酶微球-膨胀海绵复合止血材料及其制备方法及应用
US11052172B2 (en) 2016-08-12 2021-07-06 Biom'up France SAS Hemostatic flowable

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2716872C (en) 2008-02-29 2015-02-10 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
BR112014030962A2 (pt) 2012-06-12 2017-06-27 Ferrosan Medical Devices As métodos para preparação e para reconstituição de uma composição seca adequada para uso em hemostase e cicatrização de feridas, e, kit hemostático
RU2700162C2 (ru) 2013-06-21 2019-09-13 Ферросан Медикал Дивайсиз А/С Расширенная под вакуумом сухая композиция и шприц для ее сохранения
EP3470094B1 (de) 2013-12-11 2020-07-22 Ferrosan Medical Devices A/S Trockenzusammensetzung mit extrusionsverstärker
CA2960309A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
CN107206165B (zh) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 用于保持并混合第一和第二物质的注射器
AU2016290433B2 (en) 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
WO2019215274A1 (en) 2018-05-09 2019-11-14 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
CN114159623B (zh) * 2020-12-12 2022-11-08 复旦大学 一种自抗凝弹性体材料及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515637A (en) * 1983-11-16 1985-05-07 Seton Company Collagen-thrombin compositions
AU726163B2 (en) * 1996-04-04 2000-11-02 Baxter Healthcare Sa Hemostatic sponge based on collagen
EP1053753A1 (de) * 1999-05-19 2000-11-22 Resorba Chirurgisches Nahtmaterial Franz Hiltner GmbH & Co. Lokaler Wirkstoffträger

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9283187B2 (en) 2011-04-27 2016-03-15 Biom'up Hemostatic compositions
US9662374B2 (en) 2011-04-27 2017-05-30 Biom'up Hemostatic compositions
US10046034B2 (en) 2011-04-27 2018-08-14 Biom'up Hemostatic compositions
US10342856B2 (en) 2011-04-27 2019-07-09 Biom'up Hemostatic compostions
CN104163779A (zh) * 2014-06-06 2014-11-26 浙江工业大学 一种管式连续化制备亚硫酸氢钠甲萘醌的方法
CN104163779B (zh) * 2014-06-06 2016-04-13 浙江工业大学 一种管式连续化制备亚硫酸氢钠甲萘醌的方法
US11052172B2 (en) 2016-08-12 2021-07-06 Biom'up France SAS Hemostatic flowable
CN111053944A (zh) * 2019-11-28 2020-04-24 中国科学院大学温州研究院(温州生物材料与工程研究所) 一种载凝血酶微球-膨胀海绵复合止血材料及其制备方法及应用

Also Published As

Publication number Publication date
WO2003094983A1 (de) 2003-11-20
AU2003232257A1 (en) 2003-11-11
EP1501558A1 (de) 2005-02-02

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Legal Events

Date Code Title Description
FZDE Discontinued