CA2474710A1 - Freeze-dried pharmaceutically acceptable inclusion complexes of propofol and cyclodextrin - Google Patents

Freeze-dried pharmaceutically acceptable inclusion complexes of propofol and cyclodextrin Download PDF

Info

Publication number
CA2474710A1
CA2474710A1 CA002474710A CA2474710A CA2474710A1 CA 2474710 A1 CA2474710 A1 CA 2474710A1 CA 002474710 A CA002474710 A CA 002474710A CA 2474710 A CA2474710 A CA 2474710A CA 2474710 A1 CA2474710 A1 CA 2474710A1
Authority
CA
Canada
Prior art keywords
propofol
cyclodextrin
pharmaceutical composition
solution
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002474710A
Other languages
English (en)
French (fr)
Inventor
Lawrence John Penkler (Deceased)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shimoda Biotech Pty Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2474710A1 publication Critical patent/CA2474710A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002474710A 2002-02-01 2003-01-29 Freeze-dried pharmaceutically acceptable inclusion complexes of propofol and cyclodextrin Abandoned CA2474710A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ZA200200929 2002-02-01
ZA2002/0929 2002-02-01
US40163302P 2002-08-06 2002-08-06
PCT/IB2003/000266 WO2003063824A2 (en) 2002-02-01 2003-01-29 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
CA2474710A1 true CA2474710A1 (en) 2003-08-07

Family

ID=27669352

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002474710A Abandoned CA2474710A1 (en) 2002-02-01 2003-01-29 Freeze-dried pharmaceutically acceptable inclusion complexes of propofol and cyclodextrin

Country Status (12)

Country Link
US (1) US20050239746A1 (enExample)
EP (1) EP1469886B8 (enExample)
JP (1) JP2005522422A (enExample)
CN (1) CN1625414A (enExample)
AT (1) ATE326985T1 (enExample)
AU (1) AU2003205930B2 (enExample)
BR (1) BR0307518A (enExample)
CA (1) CA2474710A1 (enExample)
DE (1) DE60305438T2 (enExample)
MX (1) MXPA04007328A (enExample)
NZ (1) NZ534598A (enExample)
WO (1) WO2003063824A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523591A (zh) * 2014-12-19 2015-04-22 西安力邦肇新生物科技有限公司 无致敏性、无痛新型丙泊酚脂肪微乳冻干制剂配方和制备方法
WO2022122992A1 (fr) 2020-12-10 2022-06-16 Centre Hospitalier Universitaire De Lille Composition pharmaceutique contenant du propofol, une cyclodextrine ou un dérivé de cyclodextrine et un sel pharmaceuticalement acceptable

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1574221T1 (sl) * 2004-03-10 2007-10-31 Shimoda Biotech Pty Ltd Stabilni sestavki diklofenaka za vbrizgavanje
US20060198891A1 (en) 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents
WO2006112276A1 (ja) 2005-04-13 2006-10-26 Otsuka Pharmaceutical Factory, Inc. プロポフォール含有脂肪乳剤
JP2009504634A (ja) * 2005-08-12 2009-02-05 ブハラット セルムズ アンド ヴァクシンズ リミテッド プロポフォールを含む水性麻酔剤組成物
KR20160033796A (ko) 2006-03-28 2016-03-28 자블린 파머슈티칼스 인코포레이티드 저 복용량의 디클로페낙 및 베타-사이클로덱스트린 제형
EP2106786A1 (de) * 2008-04-04 2009-10-07 Roewer, Norbert, Univ.-Prof. Dr. med. Pharmazeutische Zubereitung mit permethyliertem Cyclodextrin
DK2484350T3 (en) * 2011-02-04 2016-08-01 Norbert Univ -Prof Dr Med Roewer A pharmaceutical composition containing a complex of a cyclodextrin with a propofolsalt
CA2852716C (en) 2011-11-29 2015-11-17 Jurox Pty Ltd Methods of preserving injectable pharmaceutical compositions comprising a cyclodextrin and a hydrophobic drug
CN103172658B (zh) * 2011-12-26 2016-01-20 宜昌人福药业有限责任公司 一种适合药用的前体药物晶型、制备方法及药用组合物
WO2014075935A1 (de) 2012-11-15 2014-05-22 Sapiotec Gmbh Delphinidinkomplex als antiphlogistischer oder immunsuppressiver wirkstoff
KR102164174B1 (ko) 2012-12-11 2020-10-12 자피오텍 게엠베하 흑색종 세포를 퇴치하기 위한 델피니딘
EP2913050A1 (de) * 2014-02-28 2015-09-02 SapioTec GmbH Verfahren zur Herstellung eines Flurankomplexes
CN111529695A (zh) * 2020-04-30 2020-08-14 首都医科大学附属北京康复医院（北京工人疗养院） 一种环糊精可溶性ace2及其制备方法和应用
KR20220057901A (ko) * 2020-10-30 2022-05-09 현대자동차주식회사 차아염소산수를 이용한 차량용 살균장치 및 그 제어방법
KR20240148426A (ko) * 2022-02-18 2024-10-11 베렌 테라퓨틱스 피.비.씨. 2-히드록시프로필-베타-사이클로덱스트린으로 고-트리글리세리드혈증을 치료

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA828580B (en) * 1981-12-23 1983-10-26 Schering Corp Interferon formulations
ZA962214B (en) * 1995-04-10 1996-10-07 Farmarc Nederland Bv Pharmaceutical composition
WO1996041646A2 (en) * 1995-06-13 1996-12-27 Dyer, Alison, Margaret Pharmaceutical compositions containing lornoxicam and cyclodextrin
PT881915E (pt) * 1996-02-19 2003-09-30 Amersham Health As Melhorias em ou relativas a agentes de contraste
US6407278B2 (en) * 1998-11-16 2002-06-18 Medimmune Oncology, Inc. Stable amorphous amifostine compositions and methods for the preparation and use of the same
US6440414B1 (en) * 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
WO2001032172A1 (en) * 1999-10-29 2001-05-10 Merck & Co., Inc. Process for formulation of carbapenem antibiotic compositions
IN187686B (enExample) * 2000-06-21 2002-06-08 Bharat Serums & Vaccines Ltd
EP1383445A4 (en) * 2001-03-20 2005-04-13 Cydex Inc FORMULATIONS WITH PROPOFOL AND A SULFOALKYL ETHER CYCLODEXTRIN

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523591A (zh) * 2014-12-19 2015-04-22 西安力邦肇新生物科技有限公司 无致敏性、无痛新型丙泊酚脂肪微乳冻干制剂配方和制备方法
CN104523591B (zh) * 2014-12-19 2019-01-18 西安力邦肇新生物科技有限公司 无致敏性、无痛丙泊酚脂肪微乳冻干制剂配方和制备方法
WO2022122992A1 (fr) 2020-12-10 2022-06-16 Centre Hospitalier Universitaire De Lille Composition pharmaceutique contenant du propofol, une cyclodextrine ou un dérivé de cyclodextrine et un sel pharmaceuticalement acceptable
FR3117337A1 (fr) 2020-12-10 2022-06-17 Centre Hospitalier Universitaire De Lille Composition pharmaceutique contenant du propofol, une cyclodextrine ou un dérivé de cyclodextrine et un sel pharmaceuticalement acceptable

Also Published As

Publication number Publication date
EP1469886B8 (en) 2008-01-09
CN1625414A (zh) 2005-06-08
EP1469886B1 (en) 2006-05-24
JP2005522422A (ja) 2005-07-28
MXPA04007328A (es) 2005-07-05
WO2003063824A3 (en) 2004-06-17
NZ534598A (en) 2004-11-26
BR0307518A (pt) 2004-12-28
US20050239746A1 (en) 2005-10-27
WO2003063824A2 (en) 2003-08-07
DE60305438T2 (de) 2006-12-21
EP1469886A2 (en) 2004-10-27
AU2003205930B2 (en) 2007-08-16
DE60305438D1 (de) 2006-06-29
ATE326985T1 (de) 2006-06-15

Similar Documents

Publication Publication Date Title
AU2003205930B2 (en) Pharmaceutical composition
AU2003205930A1 (en) Pharmaceutical composition
KR100349754B1 (ko) 제약조성물
US7678776B2 (en) Inclusion complexes of butylphthalide with cyclodextrin or its derivatives, a process for their preparation and the use thereof
BG64584B1 (bg) Фармацевтични състави, съдържащи вориконазол
JP2003535893A (ja) 透明水性麻酔剤組成物
WO1996032135A1 (en) Pharmaceutical composition
US6077871A (en) Droloxifene pharmaceutical compositions
EP0268215B1 (en) Inclusion complex of ibuproxam with beta-cyclodextrin, a process for preparing the same and a pharmaceutical preparation containing the same
WO1996041646A2 (en) Pharmaceutical compositions containing lornoxicam and cyclodextrin
AU777684B2 (en) Formulations for parenteral use of estramustine phosphate and sulfoalkyl ether cyclodextrins
ZA200406021B (en) Pharmaceutical composition
KR20040091004A (ko) 약제학적 조성물
CA2486571C (en) Pharmaceutical composition
KR20090069264A (ko) 주사 투여용 약제학적 조성물
AU777763B2 (en) Formulations for parenteral use of estramustine phosphate with improved pharmacological properties
MXPA06008648A (es) Composiciones farmaceuticas de antagonistas del receptor de neuroquinina y ciclodextrina y metodos para una tolerancia mejorada en el sitio de inyeccion.
JPH07316065A (ja) Ｆｒ９０１４６９物質製剤
EP4482463A1 (en) Solid and oral etoposide toniribate compositions
US20260000695A1 (en) Solid and oral etoposide toniribate compositions
MXPA98009888A (en) Pharmaceutical compositions of droloxif

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20130125