CA2474588A1 - 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence - Google Patents
2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence Download PDFInfo
- Publication number
- CA2474588A1 CA2474588A1 CA002474588A CA2474588A CA2474588A1 CA 2474588 A1 CA2474588 A1 CA 2474588A1 CA 002474588 A CA002474588 A CA 002474588A CA 2474588 A CA2474588 A CA 2474588A CA 2474588 A1 CA2474588 A1 CA 2474588A1
- Authority
- CA
- Canada
- Prior art keywords
- imino
- imidazolidine
- compound according
- chloro
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 206010046543 Urinary incontinence Diseases 0.000 title claims abstract description 13
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02002352.9 | 2002-01-31 | ||
| EP02002352A EP1333028A1 (en) | 2002-01-31 | 2002-01-31 | 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence |
| PCT/EP2002/014299 WO2003064398A1 (en) | 2002-01-31 | 2002-12-16 | 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2474588A1 true CA2474588A1 (en) | 2003-08-07 |
Family
ID=8185397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002474588A Abandoned CA2474588A1 (en) | 2002-01-31 | 2002-12-16 | 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP1333028A1 (enExample) |
| JP (1) | JP2005516066A (enExample) |
| KR (1) | KR20040074134A (enExample) |
| CN (1) | CN1617857A (enExample) |
| AR (1) | AR038380A1 (enExample) |
| BR (1) | BR0215560A (enExample) |
| CA (1) | CA2474588A1 (enExample) |
| EA (1) | EA200400877A1 (enExample) |
| EC (1) | ECSP045210A (enExample) |
| HR (1) | HRP20040691A2 (enExample) |
| HU (1) | HUP0402654A2 (enExample) |
| IL (1) | IL162776A0 (enExample) |
| MX (1) | MXPA04007250A (enExample) |
| NO (1) | NO20043614L (enExample) |
| PE (1) | PE20030819A1 (enExample) |
| PL (1) | PL369826A1 (enExample) |
| TW (1) | TW200418462A (enExample) |
| UY (1) | UY27628A1 (enExample) |
| WO (1) | WO2003064398A1 (enExample) |
| ZA (1) | ZA200405173B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4168086B1 (ja) * | 2008-04-16 | 2008-10-22 | 国立大学法人福井大学 | イミダゾリン誘導体 |
| BRPI0912604A2 (pt) * | 2008-05-13 | 2019-09-10 | Allergan Inc | quinolinilmetilimidazóis como agentes terapêuticos |
| BRPI0913019A2 (pt) | 2008-05-13 | 2015-10-13 | Allergan Inc | naftilmetilimidazóis para o tratamento de incontinência urinária por estresse |
| ES2665293T3 (es) * | 2008-06-09 | 2018-04-25 | Allergan, Inc. | Compuesto para tratar estados con mediación alfa-adrenérgica |
| US8063231B2 (en) * | 2008-06-09 | 2011-11-22 | Allergan, Inc. | Methods of treating alpha adrenergic mediated conditions |
| US9034910B2 (en) | 2008-06-09 | 2015-05-19 | Allergan, Inc. | Methods of treating alpha adrenergic mediated conditions |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2220906A1 (de) * | 1972-04-28 | 1973-11-15 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung |
| DE2259160A1 (de) * | 1972-12-02 | 1974-06-06 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylaminoimidazoline, deren saeureadditionssalze und verfahren zur herstellung derselben sowie ihre verwendung als arzneimittel |
| AT333749B (de) * | 1974-07-03 | 1976-12-10 | Chemie Linz Ag | Verfahren zur herstellung von neuen 2-arylamino-2-imidazolinderivaten |
| MTP837B (en) * | 1977-11-07 | 1979-10-22 | Hoffman La Roche And Co Aktien | Derivatives 2 finino-imidazolidire |
| DE3514351A1 (de) * | 1985-04-20 | 1986-11-06 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue substituierte 2-(n-alkinyl-n-phenyl)amino)-imidazolinderivate, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
| DE19514579A1 (de) * | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
| SG72827A1 (en) * | 1997-06-23 | 2000-05-23 | Hoffmann La Roche | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives |
| DE19740176C2 (de) * | 1997-09-12 | 2000-04-06 | Lemfoerder Metallwaren Ag | Handschaltvorrichtung für ein Kraftfahrzeug |
-
2002
- 2002-01-31 EP EP02002352A patent/EP1333028A1/en not_active Withdrawn
- 2002-12-16 BR BR0215560-5A patent/BR0215560A/pt not_active Application Discontinuation
- 2002-12-16 EP EP02795198A patent/EP1472231A1/en not_active Withdrawn
- 2002-12-16 CN CNA028277376A patent/CN1617857A/zh active Pending
- 2002-12-16 HR HRP20040691 patent/HRP20040691A2/xx not_active Application Discontinuation
- 2002-12-16 PL PL02369826A patent/PL369826A1/xx not_active Application Discontinuation
- 2002-12-16 CA CA002474588A patent/CA2474588A1/en not_active Abandoned
- 2002-12-16 EA EA200400877A patent/EA200400877A1/ru unknown
- 2002-12-16 KR KR10-2004-7011589A patent/KR20040074134A/ko not_active Withdrawn
- 2002-12-16 JP JP2003564021A patent/JP2005516066A/ja active Pending
- 2002-12-16 HU HU0402654A patent/HUP0402654A2/hu unknown
- 2002-12-16 WO PCT/EP2002/014299 patent/WO2003064398A1/en not_active Ceased
- 2002-12-16 MX MXPA04007250A patent/MXPA04007250A/es unknown
- 2002-12-16 IL IL16277602A patent/IL162776A0/xx unknown
- 2002-12-25 TW TW091137287A patent/TW200418462A/zh unknown
-
2003
- 2003-01-29 UY UY27628A patent/UY27628A1/es not_active Application Discontinuation
- 2003-01-30 PE PE2003000103A patent/PE20030819A1/es not_active Application Discontinuation
- 2003-01-31 AR ARP030100289A patent/AR038380A1/es not_active Application Discontinuation
-
2004
- 2004-06-29 ZA ZA200405173A patent/ZA200405173B/xx unknown
- 2004-07-28 EC EC2004005210A patent/ECSP045210A/es unknown
- 2004-08-30 NO NO20043614A patent/NO20043614L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| UY27628A1 (es) | 2003-08-29 |
| AR038380A1 (es) | 2005-01-12 |
| KR20040074134A (ko) | 2004-08-21 |
| CN1617857A (zh) | 2005-05-18 |
| ZA200405173B (en) | 2005-06-21 |
| TW200418462A (en) | 2004-10-01 |
| HRP20040691A2 (en) | 2004-12-31 |
| NO20043614L (no) | 2004-08-30 |
| ECSP045210A (es) | 2004-09-28 |
| EP1472231A1 (en) | 2004-11-03 |
| EP1333028A1 (en) | 2003-08-06 |
| JP2005516066A (ja) | 2005-06-02 |
| HUP0402654A2 (hu) | 2005-03-29 |
| IL162776A0 (en) | 2005-11-20 |
| WO2003064398A1 (en) | 2003-08-07 |
| BR0215560A (pt) | 2004-12-21 |
| PE20030819A1 (es) | 2003-10-20 |
| EA200400877A1 (ru) | 2005-02-24 |
| PL369826A1 (en) | 2005-05-02 |
| MXPA04007250A (es) | 2004-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |