CA2464067C - Method for treating non-neuropathic pain - Google Patents
Method for treating non-neuropathic pain Download PDFInfo
- Publication number
- CA2464067C CA2464067C CA2464067A CA2464067A CA2464067C CA 2464067 C CA2464067 C CA 2464067C CA 2464067 A CA2464067 A CA 2464067A CA 2464067 A CA2464067 A CA 2464067A CA 2464067 C CA2464067 C CA 2464067C
- Authority
- CA
- Canada
- Prior art keywords
- pain
- composition
- lidocaine
- patch
- neuropathic pain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000004296 neuralgia Diseases 0.000 title claims abstract description 68
- 208000021722 neuropathic pain Diseases 0.000 title claims abstract description 63
- 238000000034 method Methods 0.000 title abstract description 16
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- 230000036407 pain Effects 0.000 claims abstract description 117
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims abstract description 67
- 229960004194 lidocaine Drugs 0.000 claims abstract description 63
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- 206010039073 rheumatoid arthritis Diseases 0.000 description 2
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- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
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- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
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- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
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- INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 description 1
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- 229960004618 prednisone Drugs 0.000 description 1
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- MVFGUOIZUNYYSO-UHFFFAOYSA-N prilocaine Chemical compound CCCNC(C)C(=O)NC1=CC=CC=C1C MVFGUOIZUNYYSO-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/045,341 US20030124174A1 (en) | 2001-10-25 | 2001-10-25 | Method for treating non-neuropathic pain |
| US10/045,341 | 2001-10-25 | ||
| PCT/US2002/034077 WO2003035000A2 (en) | 2001-10-25 | 2002-10-23 | Method for treating non-neuropathic pain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2464067A1 CA2464067A1 (en) | 2003-05-01 |
| CA2464067C true CA2464067C (en) | 2011-03-22 |
Family
ID=21937331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2464067A Expired - Fee Related CA2464067C (en) | 2001-10-25 | 2002-10-23 | Method for treating non-neuropathic pain |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20030124174A1 (enExample) |
| EP (1) | EP1446087A4 (enExample) |
| JP (3) | JP2005506995A (enExample) |
| CN (1) | CN1571656B (enExample) |
| CA (1) | CA2464067C (enExample) |
| WO (1) | WO2003035000A2 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030124174A1 (en) * | 2001-10-25 | 2003-07-03 | Endo Pharmaceuticals, Inc | Method for treating non-neuropathic pain |
| US20030118632A1 (en) * | 2001-12-26 | 2003-06-26 | Larry Caldwell | Methods and compositions for treating carpal tunnel syndrome |
| DE10332487A1 (de) * | 2003-07-16 | 2005-02-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol für die Behandlung von chronisch nozizeptiven Schmerzen |
| US20050089559A1 (en) * | 2003-10-23 | 2005-04-28 | Istvan Szelenyi | Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
| US7906520B2 (en) | 2003-11-13 | 2011-03-15 | The General Hospital Corporation | Methods for treating pain |
| US20050112183A1 (en) * | 2003-11-25 | 2005-05-26 | Galer Bradley S. | Compositions and methods for treating neuropathic sensory loss |
| US8569277B2 (en) * | 2004-08-11 | 2013-10-29 | Palo Alto Investors | Methods of treating a subject for a condition |
| WO2006036936A2 (en) * | 2004-09-27 | 2006-04-06 | Bridge Pharma, Inc. | The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents |
| JP4921739B2 (ja) * | 2005-08-10 | 2012-04-25 | 久光製薬株式会社 | 皮膚刺激を低減した貼付剤 |
| US7592458B2 (en) * | 2006-07-21 | 2009-09-22 | Wright George E | Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain |
| EP2484347A1 (en) | 2006-11-03 | 2012-08-08 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
| US8549015B2 (en) * | 2007-05-01 | 2013-10-01 | Giancarlo Barolat | Method and system for distinguishing nociceptive pain from neuropathic pain |
| JP5392495B2 (ja) * | 2007-11-11 | 2014-01-22 | 株式会社 メドレックス | リドカインテープ剤 |
| US20090297591A1 (en) * | 2008-05-30 | 2009-12-03 | Orient Pharma Co., Ltd. | Compositions And Methods For The Transdermal Delivery Of Pharmaceutical Compounds |
| US9012477B2 (en) * | 2009-01-06 | 2015-04-21 | Nuvo Research Inc. | Method of treating neuropathic pain |
| EP2413837A4 (en) * | 2009-04-01 | 2013-10-23 | Jie Zhang | METHODS FOR TREATING MYOFASCIAL, MUSCLE AND / OR BACK PAIN |
| MX2011011698A (es) * | 2009-05-04 | 2012-02-29 | Zars Pharma Inc | Metodo para tratar dolores asociados con neuroma, entrapamiento nervioso y otras condiciones. |
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2002
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- 2002-10-23 CA CA2464067A patent/CA2464067C/en not_active Expired - Fee Related
- 2002-10-23 WO PCT/US2002/034077 patent/WO2003035000A2/en not_active Ceased
- 2002-10-23 CN CN028206193A patent/CN1571656B/zh not_active Expired - Fee Related
- 2002-10-23 EP EP02784262A patent/EP1446087A4/en not_active Withdrawn
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2006
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2009
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2010
- 2010-05-28 JP JP2010122735A patent/JP2010202663A/ja active Pending
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|---|---|
| CN1571656A (zh) | 2005-01-26 |
| EP1446087A4 (en) | 2010-06-09 |
| CA2464067A1 (en) | 2003-05-01 |
| WO2003035000A3 (en) | 2004-05-13 |
| JP2010202663A (ja) | 2010-09-16 |
| JP2005506995A (ja) | 2005-03-10 |
| JP2010065059A (ja) | 2010-03-25 |
| EP1446087A2 (en) | 2004-08-18 |
| CN1571656B (zh) | 2010-04-07 |
| US20060147510A1 (en) | 2006-07-06 |
| WO2003035000A2 (en) | 2003-05-01 |
| US20030124174A1 (en) | 2003-07-03 |
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