CA2458360A1 - Detection par procedes optiques des potentiels transmembranaires - Google Patents
Detection par procedes optiques des potentiels transmembranaires Download PDFInfo
- Publication number
- CA2458360A1 CA2458360A1 CA002458360A CA2458360A CA2458360A1 CA 2458360 A1 CA2458360 A1 CA 2458360A1 CA 002458360 A CA002458360 A CA 002458360A CA 2458360 A CA2458360 A CA 2458360A CA 2458360 A1 CA2458360 A1 CA 2458360A1
- Authority
- CA
- Canada
- Prior art keywords
- formula
- group
- independently
- compound
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract 6
- 238000001514 detection method Methods 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 9
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract 6
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 claims 7
- -1 2,3-butanediyl Chemical group 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 229910052760 oxygen Inorganic materials 0.000 claims 5
- 229910052717 sulfur Chemical group 0.000 claims 5
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 4
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 4
- 239000001301 oxygen Substances 0.000 claims 4
- 239000011593 sulfur Chemical group 0.000 claims 4
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical compound C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 claims 2
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 2
- UORVGPXVDQYIDP-UHFFFAOYSA-N borane Chemical compound B UORVGPXVDQYIDP-UHFFFAOYSA-N 0.000 claims 2
- 229910052794 bromium Inorganic materials 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 235000001671 coumarin Nutrition 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 229910052731 fluorine Inorganic materials 0.000 claims 2
- 229910052740 iodine Inorganic materials 0.000 claims 2
- 125000005647 linker group Chemical group 0.000 claims 2
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims 2
- 230000007935 neutral effect Effects 0.000 claims 2
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 claims 2
- 125000005010 perfluoroalkyl group Chemical group 0.000 claims 2
- 150000008104 phosphatidylethanolamines Chemical class 0.000 claims 2
- 125000006239 protecting group Chemical group 0.000 claims 2
- CUJPFPXNDSIBPG-UHFFFAOYSA-N 1,3-propanediyl Chemical group [CH2]C[CH2] CUJPFPXNDSIBPG-UHFFFAOYSA-N 0.000 claims 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical group [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000000732 arylene group Chemical group 0.000 claims 1
- 229910000085 borane Inorganic materials 0.000 claims 1
- 229910052796 boron Inorganic materials 0.000 claims 1
- 229960000956 coumarin Drugs 0.000 claims 1
- 150000004775 coumarins Chemical class 0.000 claims 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 claims 1
- 125000004404 heteroalkyl group Chemical group 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 125000002524 organometallic group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000002194 synthesizing effect Effects 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
- 150000003732 xanthenes Chemical class 0.000 claims 1
- 239000012528 membrane Substances 0.000 abstract 9
- 230000005281 excited state Effects 0.000 abstract 2
- 238000002866 fluorescence resonance energy transfer Methods 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Landscapes
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/481,977 | 1995-06-07 | ||
| US08/481,977 US5661035A (en) | 1995-06-07 | 1995-06-07 | Voltage sensing by fluorescence resonance energy transfer |
| CA002223927A CA2223927C (fr) | 1995-06-07 | 1996-06-06 | Detection par procedes optiques des potentiels transmembranaires |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002223927A Division CA2223927C (fr) | 1995-06-07 | 1996-06-06 | Detection par procedes optiques des potentiels transmembranaires |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2458360A1 true CA2458360A1 (fr) | 1996-12-19 |
| CA2458360C CA2458360C (fr) | 2010-12-07 |
Family
ID=32471054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2458360A Expired - Lifetime CA2458360C (fr) | 1995-06-07 | 1996-06-06 | Detection par procedes optiques des potentiels transmembranaires |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2458360C (fr) |
-
1996
- 1996-06-06 CA CA2458360A patent/CA2458360C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2458360C (fr) | 2010-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20160606 |