CA2452677A1 - Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides - Google Patents

Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides Download PDF

Info

Publication number
CA2452677A1
CA2452677A1 CA002452677A CA2452677A CA2452677A1 CA 2452677 A1 CA2452677 A1 CA 2452677A1 CA 002452677 A CA002452677 A CA 002452677A CA 2452677 A CA2452677 A CA 2452677A CA 2452677 A1 CA2452677 A1 CA 2452677A1
Authority
CA
Canada
Prior art keywords
factor
factor vii
related polypeptide
vii
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002452677A
Other languages
English (en)
French (fr)
Inventor
Rasmus Rojkjaer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk Health Care AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2452677A1 publication Critical patent/CA2452677A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002452677A 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides Abandoned CA2452677A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20
PCT/DK2002/000505 WO2003007983A1 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides

Publications (1)

Publication Number Publication Date
CA2452677A1 true CA2452677A1 (en) 2003-01-30

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002452677A Abandoned CA2452677A1 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides

Country Status (16)

Country Link
EP (1) EP1411973A1 (zh)
JP (1) JP2004534855A (zh)
KR (1) KR20040015821A (zh)
CN (1) CN1304050C (zh)
AU (1) AU2002354846B2 (zh)
BR (1) BR0211256A (zh)
CA (1) CA2452677A1 (zh)
CZ (1) CZ200439A3 (zh)
HU (1) HUP0400976A3 (zh)
IL (1) IL159622A0 (zh)
MX (1) MXPA04000415A (zh)
NO (1) NO20040235L (zh)
PL (1) PL369077A1 (zh)
RU (1) RU2298416C2 (zh)
WO (1) WO2003007983A1 (zh)
ZA (1) ZA200400012B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0302052A3 (en) 1999-07-14 2005-12-28 Novo Nordisk Healthcare Ag Use of fviia or a tissue factor antagonist for regulating gene expression and cell migration or chemotaxis
CN101870729A (zh) 2003-09-09 2010-10-27 诺和诺德医疗保健公司 凝固因子ⅶ多肽
TW200529870A (en) * 2003-11-20 2005-09-16 Novo Nordisk Healthcare Ag Therapeutic use of factor XI
JP2007520530A (ja) * 2004-02-05 2007-07-26 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 外傷の遅発型合併症の治療のための、VIIa因子又はVIIa因子等価物の使用
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
DK2379096T3 (da) 2008-12-19 2019-11-25 Baxalta GmbH TFPI-inhibitorer og fremgangsmåder til anvendelse
US8450275B2 (en) 2010-03-19 2013-05-28 Baxter International Inc. TFPI inhibitors and methods of use
WO2012045569A1 (en) 2010-10-06 2012-04-12 Medimmune Limited Factor ii and fibrinogen for treatment of haemostatic disorders
HUE046572T2 (hu) 2012-03-21 2020-03-30 Baxalta GmbH TFPI inhibitorok és alkalmazási eljárások
CN105939607A (zh) * 2014-01-31 2016-09-14 达纳-法伯癌症研究所股份有限公司 二氢蝶啶酮衍生物及其用途
EP3307728A4 (en) 2015-06-12 2019-07-17 Dana Farber Cancer Institute, Inc. ASSOCIATION THERAPY USING TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS
EP3380100A4 (en) 2015-11-25 2019-10-02 Dana-Farber Cancer Institute, Inc. BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
JPH0780783B2 (ja) * 1985-11-26 1995-08-30 ノボ ノルディスク アクティーゼルスカブ 出血障害の治療のための第▲VII▼a因子を含有する治療組成物
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2676231A1 (fr) * 1991-05-07 1992-11-13 Aetsrn Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.
AU2001287550B2 (en) * 2000-09-13 2007-03-22 Novo Nordisk Health Care Ag Human coagulation factor VII variants

Also Published As

Publication number Publication date
CN1304050C (zh) 2007-03-14
JP2004534855A (ja) 2004-11-18
RU2298416C2 (ru) 2007-05-10
MXPA04000415A (es) 2004-11-22
RU2004105031A (ru) 2005-04-20
AU2002354846B2 (en) 2007-08-02
KR20040015821A (ko) 2004-02-19
CZ200439A3 (cs) 2005-03-16
CN1556710A (zh) 2004-12-22
PL369077A1 (en) 2005-04-18
EP1411973A1 (en) 2004-04-28
NO20040235L (no) 2004-03-17
BR0211256A (pt) 2004-07-27
ZA200400012B (en) 2004-08-17
HUP0400976A3 (en) 2006-01-30
WO2003007983A1 (en) 2003-01-30
IL159622A0 (en) 2004-06-01
HUP0400976A2 (hu) 2004-08-30

Similar Documents

Publication Publication Date Title
US7125846B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
US20070027077A1 (en) Pharmaceutical compositions comprising factor VII polypeptides and factor XI polypeptides
US7078479B2 (en) Pharmaceutical composition comprising factor VII polypeptides and alpha2-antiplasmin polypeptides
US20080069810A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides and TAFI Polypeptides
EP1446150A1 (en) Pharmaceutical composition comprising factor vii polypeptides and protein c inhibitors
AU2002354846B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
US20030119743A1 (en) Pharmaceutical composition comprising factor VII polypeptides and tissue plasminogen inhibitors
US20060030531A1 (en) Pharmaceutical composition comprising factor VII polypeptide and PAI-1 polypeptide
AU2002354846A1 (en) Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
US20030119741A1 (en) Pharmaceutical composition comprising factor VII polypeptides and aprotinin polypeptides
EP1446148A1 (en) Pharmaceutical composition comprising a factor vii polypeptide and epsilon-aminocapronic acid
US20080075709A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides And Thrombomodulin Polypeptides
US20060025336A1 (en) Pharmaceutical compositions comprising combinations of factor VII polypeptides and aprotinin polypeptides
AU2002340779B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
AU2002340779A1 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
EP1446155A1 (en) Pharmaceutical composition comprising factor vii polypeptides and aprotinin polypeptides
AU2002340778B2 (en) Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides
EP1446145A1 (en) Pharmaceutical composition comprising factor vii polypeptides and tafi polypeptides
AU2002340778A1 (en) Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides
EP1446152A1 (en) Pharmaceutical composition comprising factor vii polypeptides and protein s inhibitors
EP1446153A1 (en) Pharmaceutical composition comprising factor vii polypeptides and tissue plasminogen inhibitors
EP1446154A1 (en) Pharmaceutical composition comprising factor vii polypeptides and alpha2 -antiplasmin polypeptides
EP1446151A1 (en) Pharmaceutical composition comprising factor vii polypeptides and thrombomodulin polypeptides

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued