CA2449259A1 - Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same - Google Patents

Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same Download PDF

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Publication number
CA2449259A1
CA2449259A1 CA002449259A CA2449259A CA2449259A1 CA 2449259 A1 CA2449259 A1 CA 2449259A1 CA 002449259 A CA002449259 A CA 002449259A CA 2449259 A CA2449259 A CA 2449259A CA 2449259 A1 CA2449259 A1 CA 2449259A1
Authority
CA
Canada
Prior art keywords
leu
gly
ala
ser
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002449259A
Other languages
English (en)
French (fr)
Inventor
Mitsuo Nishikawa
Radoje T. Drmanac
Ivan Labat
Juhi Lee
Y. Tom Tang
Birgit Stache-Crain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kirin Pharma KK
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2449259A1 publication Critical patent/CA2449259A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002449259A 2001-06-11 2002-06-11 Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same Abandoned CA2449259A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29728601P 2001-06-11 2001-06-11
US60/297,286 2001-06-11
PCT/JP2002/005807 WO2002100898A2 (en) 2001-06-11 2002-06-11 Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same

Publications (1)

Publication Number Publication Date
CA2449259A1 true CA2449259A1 (en) 2002-12-19

Family

ID=23145656

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002449259A Abandoned CA2449259A1 (en) 2001-06-11 2002-06-11 Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same

Country Status (6)

Country Link
US (2) US7320880B2 (enExample)
EP (1) EP1395610A2 (enExample)
JP (1) JP4251983B2 (enExample)
AU (1) AU2002304249A1 (enExample)
CA (1) CA2449259A1 (enExample)
WO (1) WO2002100898A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7320880B2 (en) 2001-06-11 2008-01-22 Nuvelo, Inc. Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same
EP1499637A1 (en) 2002-04-26 2005-01-26 Kirin Beer Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell or hematopoietic progenitor cell, and dna coding for the same
ATE466106T1 (de) * 2003-10-10 2010-05-15 Deutsches Krebsforsch Zusammensetzungen für die diagnose und therapie von erkrankungen, die im zusammenhang mit einer anomalen expression von futrinen (r-spondinen) stehen
WO2005103234A1 (en) 2004-04-23 2005-11-03 Héma-Québec A new method of expanding cord blood cells
CA2644046A1 (en) * 2006-02-28 2007-09-07 Trustees Of Boston University Metabolic regulators and uses thereof
HUE027179T2 (en) 2006-10-20 2016-10-28 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Angiogenesis and vasculogenesis modulator for Rspond
ES2694018T3 (es) 2007-07-02 2018-12-17 Oncomed Pharmaceuticals, Inc. Composiciones y métodos para el tratamiento y el diagnóstico del cáncer
WO2013012747A1 (en) 2011-07-15 2013-01-24 Oncomed Pharmaceuticals, Inc. Rspo binding agents and uses thereof
CN104854132A (zh) 2012-07-13 2015-08-19 昂考梅德药品有限公司 Rspo3结合剂及其用途
WO2015004248A2 (en) * 2013-07-12 2015-01-15 B.R.A.H.M.S Gmbh Augurin immunoassay
WO2016044295A1 (en) 2014-09-16 2016-03-24 Oncomed Pharmaceuticals, Inc. Treatment of fibrotic diseases
CN115991737B (zh) * 2022-07-26 2023-08-25 河北生命原点生物科技有限公司 活性肽在制备促进脐带造血干细胞增殖的药物或培养基中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0953354A4 (en) 1996-08-13 2002-10-23 Fujisawa Pharmaceutical Co HEMATOPOIETIC STEM CELLS PROLIFERING ACTIVE SUBSTANCES
US6541217B2 (en) 1996-08-27 2003-04-01 Kyowa Hakko Kogyo Co., Ltd. Hematopoietic stem cell growth factor (SCGF)
WO1999003980A1 (en) * 1997-07-16 1999-01-28 Kirin Beer Kabushiki Kaisha Agm-derived stroma cells
JPH11155574A (ja) 1997-12-01 1999-06-15 Eisai Co Ltd Ｍｄｃ遺伝子ファミリーに属する新規蛋白質およびそれをコードするｄｎａ
CA2373227A1 (en) 1999-05-05 2000-11-09 Ohio University Growth hormone-regulatable brown adipose tissue genes and proteins and uses thereof
WO2002060942A2 (en) 2001-01-31 2002-08-08 Incyte Genomics, Inc. Protein modification and maintenance molecules
US6783969B1 (en) 2001-03-05 2004-08-31 Nuvelo, Inc. Cathepsin V-like polypeptides
US7320880B2 (en) 2001-06-11 2008-01-22 Nuvelo, Inc. Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same

Also Published As

Publication number Publication date
WO2002100898A2 (en) 2002-12-19
US7320880B2 (en) 2008-01-22
JP4251983B2 (ja) 2009-04-08
JP2005507240A (ja) 2005-03-17
EP1395610A2 (en) 2004-03-10
WO2002100898A3 (en) 2003-05-30
AU2002304249A1 (en) 2002-12-23
US20080227200A1 (en) 2008-09-18
US20040220396A1 (en) 2004-11-04

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued