JP4251983B2 - 造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna - Google Patents

造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna Download PDF

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JP4251983B2
JP4251983B2 JP2003503664A JP2003503664A JP4251983B2 JP 4251983 B2 JP4251983 B2 JP 4251983B2 JP 2003503664 A JP2003503664 A JP 2003503664A JP 2003503664 A JP2003503664 A JP 2003503664A JP 4251983 B2 JP4251983 B2 JP 4251983B2
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cells
hematopoietic stem
seq
scr
hematopoietic
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JP2005507240A (ja
JP2005507240A5 (enExample
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光郎 西川
ティー. ドルマナック,ラドジェ
ラバット,アイヴァン
リー,ジュイ
ワイ. タン,トム
スタシェ−クレイン,バージット
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Kyowa Kirin Co Ltd
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Kyowa Hakko Kirin Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003503664A 2001-06-11 2002-06-11 造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna Expired - Lifetime JP4251983B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29728601P 2001-06-11 2001-06-11
PCT/JP2002/005807 WO2002100898A2 (en) 2001-06-11 2002-06-11 Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same

Publications (3)

Publication Number Publication Date
JP2005507240A JP2005507240A (ja) 2005-03-17
JP2005507240A5 JP2005507240A5 (enExample) 2006-01-05
JP4251983B2 true JP4251983B2 (ja) 2009-04-08

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JP2003503664A Expired - Lifetime JP4251983B2 (ja) 2001-06-11 2002-06-11 造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna

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US (2) US7320880B2 (enExample)
EP (1) EP1395610A2 (enExample)
JP (1) JP4251983B2 (enExample)
AU (1) AU2002304249A1 (enExample)
CA (1) CA2449259A1 (enExample)
WO (1) WO2002100898A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2449259A1 (en) 2001-06-11 2002-12-19 Kirin Beer Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same
WO2003091280A1 (en) * 2002-04-26 2003-11-06 Kirin Beer Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell or hematopoietic progenitor cell, and dna coding for the same
DK1673475T3 (da) * 2003-10-10 2010-07-19 Deutsches Krebsforsch Sammensætninger til diagnose og terapi af sygdomme, som er forbundet med aberrant ekspression af futriner (R-Spondiner) og/eller Wnt
WO2005103234A1 (en) 2004-04-23 2005-11-03 Héma-Québec A new method of expanding cord blood cells
WO2007100695A2 (en) * 2006-02-28 2007-09-07 Trustees Of Boston University Metabolic regulators and uses thereof
WO2008046649A1 (en) 2006-10-20 2008-04-24 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Rspondins as modulators of angiogenesis and vasculogenesis
PT2173379E (pt) 2007-07-02 2015-11-24 Oncomed Pharm Inc Composições e métodos para o tratamento e diagnóstico de cancro
EP2731625B1 (en) 2011-07-15 2018-04-18 OncoMed Pharmaceuticals, Inc. Rspo binding agents and uses thereof
CN104854132A (zh) 2012-07-13 2015-08-19 昂考梅德药品有限公司 Rspo3结合剂及其用途
US10024872B2 (en) 2013-07-12 2018-07-17 B.R.A.H.M.S Gmbh Augurin immunoassay
MA40574A (fr) 2014-09-16 2016-03-24 Oncomed Pharm Inc Traitement de maladies fibrotiques
CN115991737B (zh) * 2022-07-26 2023-08-25 河北生命原点生物科技有限公司 活性肽在制备促进脐带造血干细胞增殖的药物或培养基中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495365B1 (en) * 1996-08-13 2002-12-17 Fujisawa Pharmaceutical Co., Ltd. Hematopoietic stem cell proliferating agents
CA2235867A1 (en) 1996-08-27 1998-03-05 Kyowa Hakko Kogyo Co., Ltd. Hematopoietic stem cell growth factor (scgf)
WO1999003980A1 (en) 1997-07-16 1999-01-28 Kirin Beer Kabushiki Kaisha Agm-derived stroma cells
JPH11155574A (ja) 1997-12-01 1999-06-15 Eisai Co Ltd Mdc遺伝子ファミリーに属する新規蛋白質およびそれをコードするdna
CA2373227A1 (en) 1999-05-05 2000-11-09 Ohio University Growth hormone-regulatable brown adipose tissue genes and proteins and uses thereof
AU2002253883A1 (en) 2001-01-31 2002-08-12 Incyte Genomics, Inc. Protein modification and maintenance molecules
US6783969B1 (en) 2001-03-05 2004-08-31 Nuvelo, Inc. Cathepsin V-like polypeptides
CA2449259A1 (en) 2001-06-11 2002-12-19 Kirin Beer Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same

Also Published As

Publication number Publication date
CA2449259A1 (en) 2002-12-19
US7320880B2 (en) 2008-01-22
JP2005507240A (ja) 2005-03-17
EP1395610A2 (en) 2004-03-10
US20080227200A1 (en) 2008-09-18
WO2002100898A3 (en) 2003-05-30
AU2002304249A1 (en) 2002-12-23
WO2002100898A2 (en) 2002-12-19
US20040220396A1 (en) 2004-11-04

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