JP4251983B2 - 造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna - Google Patents

造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna Download PDF

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JP4251983B2
JP4251983B2 JP2003503664A JP2003503664A JP4251983B2 JP 4251983 B2 JP4251983 B2 JP 4251983B2 JP 2003503664 A JP2003503664 A JP 2003503664A JP 2003503664 A JP2003503664 A JP 2003503664A JP 4251983 B2 JP4251983 B2 JP 4251983B2
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cells
hematopoietic stem
seq
scr
hematopoietic
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JP2005507240A (ja
JP2005507240A5 (enExample
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光郎 西川
ティー. ドルマナック,ラドジェ
ラバット,アイヴァン
リー,ジュイ
ワイ. タン,トム
スタシェ−クレイン,バージット
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Kyowa Kirin Co Ltd
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Kyowa Hakko Kirin Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003503664A 2001-06-11 2002-06-11 造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna Expired - Lifetime JP4251983B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29728601P 2001-06-11 2001-06-11
PCT/JP2002/005807 WO2002100898A2 (en) 2001-06-11 2002-06-11 Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same

Publications (3)

Publication Number Publication Date
JP2005507240A JP2005507240A (ja) 2005-03-17
JP2005507240A5 JP2005507240A5 (enExample) 2006-01-05
JP4251983B2 true JP4251983B2 (ja) 2009-04-08

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JP2003503664A Expired - Lifetime JP4251983B2 (ja) 2001-06-11 2002-06-11 造血幹細胞または造血前駆細胞の増殖または生存を支持し得るポリペプチドおよびそれをコードするdna

Country Status (6)

Country Link
US (2) US7320880B2 (enExample)
EP (1) EP1395610A2 (enExample)
JP (1) JP4251983B2 (enExample)
AU (1) AU2002304249A1 (enExample)
CA (1) CA2449259A1 (enExample)
WO (1) WO2002100898A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7320880B2 (en) 2001-06-11 2008-01-22 Nuvelo, Inc. Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same
EP1499637A1 (en) 2002-04-26 2005-01-26 Kirin Beer Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell or hematopoietic progenitor cell, and dna coding for the same
ATE466106T1 (de) * 2003-10-10 2010-05-15 Deutsches Krebsforsch Zusammensetzungen für die diagnose und therapie von erkrankungen, die im zusammenhang mit einer anomalen expression von futrinen (r-spondinen) stehen
WO2005103234A1 (en) 2004-04-23 2005-11-03 Héma-Québec A new method of expanding cord blood cells
CA2644046A1 (en) * 2006-02-28 2007-09-07 Trustees Of Boston University Metabolic regulators and uses thereof
HUE027179T2 (en) 2006-10-20 2016-10-28 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Angiogenesis and vasculogenesis modulator for Rspond
ES2694018T3 (es) 2007-07-02 2018-12-17 Oncomed Pharmaceuticals, Inc. Composiciones y métodos para el tratamiento y el diagnóstico del cáncer
WO2013012747A1 (en) 2011-07-15 2013-01-24 Oncomed Pharmaceuticals, Inc. Rspo binding agents and uses thereof
CN104854132A (zh) 2012-07-13 2015-08-19 昂考梅德药品有限公司 Rspo3结合剂及其用途
WO2015004248A2 (en) * 2013-07-12 2015-01-15 B.R.A.H.M.S Gmbh Augurin immunoassay
WO2016044295A1 (en) 2014-09-16 2016-03-24 Oncomed Pharmaceuticals, Inc. Treatment of fibrotic diseases
CN115991737B (zh) * 2022-07-26 2023-08-25 河北生命原点生物科技有限公司 活性肽在制备促进脐带造血干细胞增殖的药物或培养基中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0953354A4 (en) 1996-08-13 2002-10-23 Fujisawa Pharmaceutical Co HEMATOPOIETIC STEM CELLS PROLIFERING ACTIVE SUBSTANCES
US6541217B2 (en) 1996-08-27 2003-04-01 Kyowa Hakko Kogyo Co., Ltd. Hematopoietic stem cell growth factor (SCGF)
WO1999003980A1 (en) * 1997-07-16 1999-01-28 Kirin Beer Kabushiki Kaisha Agm-derived stroma cells
JPH11155574A (ja) 1997-12-01 1999-06-15 Eisai Co Ltd Mdc遺伝子ファミリーに属する新規蛋白質およびそれをコードするdna
CA2373227A1 (en) 1999-05-05 2000-11-09 Ohio University Growth hormone-regulatable brown adipose tissue genes and proteins and uses thereof
WO2002060942A2 (en) 2001-01-31 2002-08-08 Incyte Genomics, Inc. Protein modification and maintenance molecules
US6783969B1 (en) 2001-03-05 2004-08-31 Nuvelo, Inc. Cathepsin V-like polypeptides
US7320880B2 (en) 2001-06-11 2008-01-22 Nuvelo, Inc. Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same

Also Published As

Publication number Publication date
WO2002100898A2 (en) 2002-12-19
US7320880B2 (en) 2008-01-22
JP2005507240A (ja) 2005-03-17
EP1395610A2 (en) 2004-03-10
WO2002100898A3 (en) 2003-05-30
AU2002304249A1 (en) 2002-12-23
CA2449259A1 (en) 2002-12-19
US20080227200A1 (en) 2008-09-18
US20040220396A1 (en) 2004-11-04

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