CA2446228A1 - Compartiment pour organe destine a un systeme de support metabolique exsanguin - Google Patents
Compartiment pour organe destine a un systeme de support metabolique exsanguin Download PDFInfo
- Publication number
- CA2446228A1 CA2446228A1 CA002446228A CA2446228A CA2446228A1 CA 2446228 A1 CA2446228 A1 CA 2446228A1 CA 002446228 A CA002446228 A CA 002446228A CA 2446228 A CA2446228 A CA 2446228A CA 2446228 A1 CA2446228 A1 CA 2446228A1
- Authority
- CA
- Canada
- Prior art keywords
- organ
- chamber
- perfusion
- ems
- support member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Mechanical Engineering (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
L'invention concerne un système de support métabolique exsanguin permettant de maintenir un organe (40) ou un tissu à un rythme métabolique sensiblement normal. Ce système comprend un compartiment pour organe (32) renfermant un récipient (33) et un élément de support (36) conçu pour empêcher tout mouvement de l'organe (40) dans le récipient (33) lors d'une perfusion et/ou d'un transport. Le compartiment pour organe (32) comprend également un conduit (43) destiné à recevoir le débit veineux sortant d'une solution de perfusion et à empêcher tout contact de cette dernière avec les surfaces externes de l'organe (40). Un conduit (47) destiné à recevoir le produit organique permet de récupérer le produit organique d'un organe fonctionnel (40) lors d'une perfusion. L'invention concerne également l'utilisation de ce compartiment pour organe (32) pour une synthèse de novo ou continue des constituants nécessaires à un entretien à long terme des organes, pour la transplantation, la réanimation et la réparation active d'organes ayant subi des lésions ischémiques chaudes durables, et pour le transport d'organes isolés.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2001/040679 WO2002089571A1 (fr) | 2001-05-04 | 2001-05-04 | Compartiment pour organe destine a un systeme de support metabolique exsanguin |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2446228A1 true CA2446228A1 (fr) | 2002-11-14 |
Family
ID=21742936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002446228A Abandoned CA2446228A1 (fr) | 2001-05-04 | 2001-05-04 | Compartiment pour organe destine a un systeme de support metabolique exsanguin |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1392113A1 (fr) |
JP (1) | JP2004529938A (fr) |
CA (1) | CA2446228A1 (fr) |
WO (1) | WO2002089571A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116391705A (zh) * | 2023-02-27 | 2023-07-07 | 中国科学院苏州生物医学工程技术研究所 | 一种用于离体器官灌流的恒温容器 |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
US20040038192A1 (en) * | 1999-04-14 | 2004-02-26 | Breonics, Inc. | System for exsanguinous metabolic support of an organ or tissue |
US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
US8304181B2 (en) | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
IL273422B (en) | 2004-10-07 | 2022-07-01 | Transmedics Inc | Methods and systems for extracorporeal organ treatment |
US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
WO2008021577A2 (fr) | 2006-01-24 | 2008-02-21 | The Board Of Trustees Of The University Of Illinois | Milieux d'hémoglobine polymérisée et leur utilisation pour isoler et transplanter des îlots de langerhans |
JP5704818B2 (ja) * | 2007-03-01 | 2015-04-22 | ライフライン サイエンティフィック インコーポレイテッド | 潅流調節 |
US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
DE102007034132B4 (de) | 2007-07-21 | 2010-04-29 | Technische Universität Dresden | Perfusionsbeutel für explantierte Organe und Organteile |
EP2178364B1 (fr) | 2007-07-21 | 2011-04-27 | Technische Universität Dresden | Système et poche de perfusion pour la conservation d'organes et de fragments d'organes sensibles à la pression |
DE102007034130B4 (de) | 2007-07-21 | 2010-11-18 | Technische Universität Dresden | Vorrichtung zur Lagerung von druckempfindlichen Organen und Organteilen |
FR2919785B1 (fr) * | 2007-08-09 | 2017-10-20 | Hemarina Sa | Utilisation d'une globine, d'un protomere de globine ou d'une hemoglobine extracellulaire pour la preservation d'organes, de tissus, ou de cellules d'organes ou de tissus, ou de culture de cellules |
US9247728B2 (en) | 2008-01-31 | 2016-02-02 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
ES2328660B1 (es) * | 2008-05-14 | 2010-10-14 | Fundacio Privada Clinic Per A La Recerca Biomedica | Dispositivo para la preservacion de un injerto hepatico en condiciones de normotermia. |
FR2965254A1 (fr) * | 2010-09-28 | 2012-03-30 | Air Liquide | Conteneur de transport et de preservation de materiels biologiques |
US9119392B2 (en) * | 2010-11-09 | 2015-09-01 | Biomedinnovations, Llc | Articulating organ support |
US9867368B2 (en) | 2011-03-15 | 2018-01-16 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
US11178866B2 (en) | 2011-03-15 | 2021-11-23 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
US8828710B2 (en) | 2011-03-15 | 2014-09-09 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
US20210392873A1 (en) | 2011-03-15 | 2021-12-23 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
US9426979B2 (en) | 2011-03-15 | 2016-08-30 | Paragonix Technologies, Inc. | Apparatus for oxygenation and perfusion of tissue for organ preservation |
WO2012125782A2 (fr) | 2011-03-15 | 2012-09-20 | Paragonix Technologies, Inc. | Appareil utilisé pour oxygéner et perfuser un tissu de l'organisme pour sa préservation |
US12096765B1 (en) | 2011-03-15 | 2024-09-24 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
US9253976B2 (en) | 2011-03-15 | 2016-02-09 | Paragonix Technologies, Inc. | Methods and devices for preserving tissues |
DK2704560T3 (da) | 2011-04-14 | 2022-05-23 | Transmedics Inc | Organbehandlingsopløsning til maskinperfusion ex-vivo af donorlunger |
WO2012170633A1 (fr) * | 2011-06-09 | 2012-12-13 | Lifeline Scientific, Inc. | Enregistrement de données pour transport et/ou stockage d'organe comprenant un biomarqueur et informations d'événements |
CN102301993B (zh) * | 2011-07-07 | 2013-04-17 | 中国人民解放军南京军区福州总医院 | 一种胰腺充氧保存运送装置及其使用方法 |
WO2013032319A1 (fr) | 2011-09-02 | 2013-03-07 | Organ Assist B.V. | Appareil, système et méthode pour le conditionnement et la conservation d'un organe d'un donneur |
ES2388223B1 (es) * | 2012-06-29 | 2013-09-02 | Grifols Sa | Dispositivo para la perfusión de un injerto hepático |
US20140017665A1 (en) | 2012-07-10 | 2014-01-16 | Lifeline Scientific, Inc. | Organ transporter with oxygen generation |
US9560846B2 (en) | 2012-08-10 | 2017-02-07 | Paragonix Technologies, Inc. | System for hypothermic transport of biological samples |
US8785116B2 (en) | 2012-08-10 | 2014-07-22 | Paragonix Technologies, Inc. | Methods for evaluating the suitability of an organ for transplant |
DK3151663T3 (da) | 2014-06-02 | 2020-11-30 | Transmedics Inc | Ex vivo-organplejesystem |
USD765874S1 (en) | 2014-10-10 | 2016-09-06 | Paragonix Technologies, Inc. | Transporter for a tissue transport system |
CA2970117A1 (fr) | 2014-12-12 | 2016-06-16 | Darren FREED | Appareil et procede de perfusion d'organe |
CN107949419B (zh) | 2015-09-09 | 2021-03-05 | 特兰斯迈迪茨公司 | 离体器官护理系统用的主动脉插管 |
CN107183005A (zh) * | 2016-05-09 | 2017-09-22 | 多伦多Xor-Labs股份有限公司 | 器官灌注的设备与方法 |
US10091986B2 (en) * | 2016-05-09 | 2018-10-09 | Xor-Labs Toronto Inc. | Organ perfusion device and method |
EP3634127A4 (fr) | 2017-06-07 | 2021-03-17 | Paragonix Technologies Inc. | Appareil pour le transport et la conservation de tissu |
JP6988286B2 (ja) * | 2017-09-08 | 2022-01-05 | 株式会社ジェイ・エム・エス | 臓器及び生体組織の輸送装置 |
JP2020007297A (ja) * | 2018-06-27 | 2020-01-16 | 株式会社Screenホールディングス | 灌流装置および灌流方法 |
CN109221087A (zh) * | 2018-09-30 | 2019-01-18 | 南京国科医工科技发展有限公司 | 离体肝脏常温携氧机械灌注系统及灌注方法 |
CN109675648A (zh) * | 2019-01-25 | 2019-04-26 | 宁夏医科大学 | 实验鼠系统解剖脏器收集盘 |
CN110663680A (zh) * | 2019-10-25 | 2020-01-10 | 上海长海医院 | 一种供肾的机器灌注保存及转运仪器 |
US11632951B2 (en) | 2020-01-31 | 2023-04-25 | Paragonix Technologies, Inc. | Apparatus for tissue transport and preservation |
CA3202658A1 (fr) * | 2020-12-22 | 2022-06-30 | Michal Wszola | Systeme de stockage ou de culture d'un organe ou d'un modele de tissu et utilisations de celui-ci |
CN113384379B (zh) * | 2021-06-17 | 2022-12-02 | 深圳华越再生医学生物科技有限公司 | 一种用以包裹移植脏器的装置 |
USD1031028S1 (en) | 2022-09-08 | 2024-06-11 | Paragonix Technologies, Inc. | Tissue suspension adaptor |
PL442287A1 (pl) * | 2022-09-14 | 2024-03-18 | Health2Organ Spółka Z Ograniczoną Odpowiedzialnością | Pojemnik na organ do przeszczepu |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3639084A (en) * | 1970-04-06 | 1972-02-01 | Baxter Laboratories Inc | Mechanism for control pulsatile fluid flow |
WO1988005261A1 (fr) * | 1987-01-16 | 1988-07-28 | Tops Systems, Inc. | Systeme de perfusion totale pour organes |
US5051352A (en) * | 1987-10-07 | 1991-09-24 | The Regents Of The University Of California | Apparatus and method of preserving the viability of animal organs |
JPH02295901A (ja) * | 1989-05-09 | 1990-12-06 | Olympus Optical Co Ltd | 臓器保存装置 |
US5386014A (en) * | 1989-11-22 | 1995-01-31 | Enzon, Inc. | Chemically modified hemoglobin as an effective, stable, non-immunogenic red blood cell substitute |
AU5375496A (en) * | 1995-03-27 | 1996-10-16 | American National Red Cross, The | Organ evaluation and resuscitation device and method |
US5586438A (en) * | 1995-03-27 | 1996-12-24 | Organ, Inc. | Portable device for preserving organs by static storage or perfusion |
US5900402A (en) * | 1997-05-29 | 1999-05-04 | Enzon, Inc. | Method of reducing side effects associated with administration of oxygen-carrying proteins |
JP2001516768A (ja) * | 1997-09-23 | 2001-10-02 | ハッサネイン,ワリード,エイチ. | 臓器を維持するための組成物、方法及び装置 |
-
2001
- 2001-05-04 CA CA002446228A patent/CA2446228A1/fr not_active Abandoned
- 2001-05-04 EP EP01933402A patent/EP1392113A1/fr not_active Withdrawn
- 2001-05-04 WO PCT/US2001/040679 patent/WO2002089571A1/fr active Application Filing
- 2001-05-04 JP JP2002586724A patent/JP2004529938A/ja active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116391705A (zh) * | 2023-02-27 | 2023-07-07 | 中国科学院苏州生物医学工程技术研究所 | 一种用于离体器官灌流的恒温容器 |
CN116391705B (zh) * | 2023-02-27 | 2023-11-24 | 中国科学院苏州生物医学工程技术研究所 | 一种用于离体器官灌流的恒温容器 |
Also Published As
Publication number | Publication date |
---|---|
EP1392113A1 (fr) | 2004-03-03 |
WO2002089571A1 (fr) | 2002-11-14 |
JP2004529938A (ja) | 2004-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |