CA2437104C - Composes d'indole - Google Patents

Composes d'indole Download PDF

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Publication number
CA2437104C
CA2437104C CA2437104A CA2437104A CA2437104C CA 2437104 C CA2437104 C CA 2437104C CA 2437104 A CA2437104 A CA 2437104A CA 2437104 A CA2437104 A CA 2437104A CA 2437104 C CA2437104 C CA 2437104C
Authority
CA
Canada
Prior art keywords
trimethoxy
indol
phenyl
methanone
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2437104A
Other languages
English (en)
Other versions
CA2437104A1 (fr
Inventor
Hsing-Pang Hsieh
Jing-Ping Liou
Jang-Yang Chang
Chun-Wei Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Health Research Institutes
Original Assignee
National Health Research Institutes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Health Research Institutes filed Critical National Health Research Institutes
Priority to CA2437104A priority Critical patent/CA2437104C/fr
Publication of CA2437104A1 publication Critical patent/CA2437104A1/fr
Application granted granted Critical
Publication of CA2437104C publication Critical patent/CA2437104C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Abstract

La présente divulgation porte sur des composés d'indole de la formule générale ( voir la formule ci-dessus), utiles dans le traitement du cancer.
CA2437104A 2003-08-13 2003-08-13 Composes d'indole Expired - Fee Related CA2437104C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2437104A CA2437104C (fr) 2003-08-13 2003-08-13 Composes d'indole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2437104A CA2437104C (fr) 2003-08-13 2003-08-13 Composes d'indole

Publications (2)

Publication Number Publication Date
CA2437104A1 CA2437104A1 (fr) 2005-02-13
CA2437104C true CA2437104C (fr) 2012-03-06

Family

ID=34140444

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2437104A Expired - Fee Related CA2437104C (fr) 2003-08-13 2003-08-13 Composes d'indole

Country Status (1)

Country Link
CA (1) CA2437104C (fr)

Also Published As

Publication number Publication date
CA2437104A1 (fr) 2005-02-13

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Effective date: 20210813