CA2429254A1 - Distribution orale de nanospheres - Google Patents

Distribution orale de nanospheres Download PDF

Info

Publication number
CA2429254A1
CA2429254A1 CA002429254A CA2429254A CA2429254A1 CA 2429254 A1 CA2429254 A1 CA 2429254A1 CA 002429254 A CA002429254 A CA 002429254A CA 2429254 A CA2429254 A CA 2429254A CA 2429254 A1 CA2429254 A1 CA 2429254A1
Authority
CA
Canada
Prior art keywords
formulation
heparin
agent
nanospheres
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002429254A
Other languages
English (en)
Inventor
James M. Dunn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
PR Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PR Pharmaceuticals Inc filed Critical PR Pharmaceuticals Inc
Publication of CA2429254A1 publication Critical patent/CA2429254A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Abstract

L'invention concerne des préparations pharmaceutiques orales nanoparticulaires et des méthodes afférentes destinées à la libération régulée d'agents macromoléculaires et/ou chimiothérapeutiques.
CA002429254A 2000-11-20 2001-11-20 Distribution orale de nanospheres Abandoned CA2429254A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25207000P 2000-11-20 2000-11-20
US60/252,070 2000-11-20
PCT/US2001/043299 WO2002041829A2 (fr) 2000-11-20 2001-11-20 Distribution orale de nanospheres

Publications (1)

Publication Number Publication Date
CA2429254A1 true CA2429254A1 (fr) 2002-05-30

Family

ID=22954465

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002429254A Abandoned CA2429254A1 (fr) 2000-11-20 2001-11-20 Distribution orale de nanospheres

Country Status (3)

Country Link
AU (1) AU2002239279A1 (fr)
CA (1) CA2429254A1 (fr)
WO (1) WO2002041829A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE537845T1 (de) * 2000-10-31 2012-01-15 Pr Pharmaceuticals Inc Verfahren zur herstellung von formulierungen zur verbesserten abgabe von bioaktiven molekülen
DK2599502T3 (en) 2003-04-11 2017-04-18 Antriabio Inc Process for Preparation of Site-Specific Protein Conjugates
EP1774971A1 (fr) * 2005-10-14 2007-04-18 Advanced in Vitro Cell Technologies, S.L. Nanoparticules comprenant de chitosane et d'héparine
EP1834636A1 (fr) * 2006-03-08 2007-09-19 Sahajanand Medical Technologies PVT. ltd Compositions comprenant des articles poreux et leurs utilisations dans des dispositifs médicaux implantables
ES2310122B1 (es) * 2007-04-20 2009-10-30 Instituto Cientifico Y Tecnologico De Navarra, S.A Nanoparticulas que comprenden una ciclodextrina y una molecula biologicamente activa y sus aplicaciones.
US8778384B2 (en) 2008-03-24 2014-07-15 Advanced Bionutrition Corporation Compositions and methods for encapsulating vaccines for the oral vaccination and boostering of fish and other animals
NO2105129T3 (fr) * 2008-03-24 2018-06-16
EP2153821A1 (fr) * 2008-08-06 2010-02-17 BioAlliance Pharma Formules orales de dérivés de camptothécine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent

Also Published As

Publication number Publication date
WO2002041829A3 (fr) 2002-07-18
WO2002041829A2 (fr) 2002-05-30
AU2002239279A1 (en) 2002-06-03

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Legal Events

Date Code Title Description
FZDE Discontinued