CA2428799A1 - Therapie combinee abaissant et regulant la tension intraoculaire - Google Patents

Therapie combinee abaissant et regulant la tension intraoculaire Download PDF

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Publication number
CA2428799A1
CA2428799A1 CA002428799A CA2428799A CA2428799A1 CA 2428799 A1 CA2428799 A1 CA 2428799A1 CA 002428799 A CA002428799 A CA 002428799A CA 2428799 A CA2428799 A CA 2428799A CA 2428799 A1 CA2428799 A1 CA 2428799A1
Authority
CA
Canada
Prior art keywords
alkyl
integer
cooh
bond
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002428799A
Other languages
English (en)
Inventor
Abbot F. Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Research LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2428799A1 publication Critical patent/CA2428799A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Abstract

L'invention porte: sur une préparation ophtalmique combinant un angiostatique et un autre composé hypotenseur et traitant le glaucome et l'hypertension oculaire, et sur une méthode de traitement du glaucome et l'hypertension oculaire.
CA002428799A 2000-11-16 2000-11-16 Therapie combinee abaissant et regulant la tension intraoculaire Abandoned CA2428799A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/031557 WO2002040030A1 (fr) 2000-11-16 2000-11-16 Therapie combinee abaissant et regulant la tension intraoculaire

Publications (1)

Publication Number Publication Date
CA2428799A1 true CA2428799A1 (fr) 2002-05-23

Family

ID=21742004

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002428799A Abandoned CA2428799A1 (fr) 2000-11-16 2000-11-16 Therapie combinee abaissant et regulant la tension intraoculaire

Country Status (5)

Country Link
EP (1) EP1341541A4 (fr)
JP (1) JP2004522711A (fr)
AU (2) AU1770901A (fr)
CA (1) CA2428799A1 (fr)
WO (1) WO2002040030A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0316290D0 (en) 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
US7579335B2 (en) 2005-01-10 2009-08-25 Glaxo Group Limited Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
TW201010727A (en) * 2008-09-03 2010-03-16 Alcon Res Ltd Pharmaceutical composition having relatively low ionic strength
EP3006453A1 (fr) 2014-10-08 2016-04-13 Cosmo Technologies Ltd. 17alpha-monoesters et 17alpha, 21-diesters de cortexolone pour utilisation dans le traitement de tumeurs
CN108066283B (zh) * 2017-12-28 2020-03-24 兆科(广州)眼科药物有限公司 一种盐酸左倍他洛尔滴眼液的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599353A (en) * 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
US4904649A (en) * 1986-05-23 1990-02-27 New England Medical Center Hospitals, Inc. Method and solution for treating glaucoma
WO1987007141A1 (fr) * 1986-05-23 1987-12-03 New England Medical Center Hospitals, Inc. Methode de traitement du glaucome
US4876250A (en) * 1988-10-31 1989-10-24 Alcon Laboratories, Inc. Methods for controlling ocular hypertension with angiostatic steroids
US5371078A (en) * 1988-10-31 1994-12-06 Alcon Laboratories, Inc. Angiostatic steroids and methods and compositions for controlling ocular hypertension
US5153192A (en) * 1990-04-09 1992-10-06 Alcon Laboratories, Inc. Thiophene sulfonamides useful as carbonic anhydrase inhibitors
US5153193A (en) * 1991-10-01 1992-10-06 Hoechst-Roussel Pharmaceuticals Incorporated Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
EP1236471A3 (fr) * 1991-11-22 2004-12-15 Alcon Laboratories, Inc. Steroides angiostatiques
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
DK1069913T3 (da) * 1998-04-07 2003-11-17 Alcon Mfg Ltd Gelatinering af ophthalmiske sammensætninger indeholdende xanthangummi
US6486208B1 (en) * 1998-09-25 2002-11-26 Alcon Laboratories, Inc. Sustained release, and comfortable opthalmic composition and method for ocular therapy

Also Published As

Publication number Publication date
AU1770901A (en) 2002-05-27
EP1341541A1 (fr) 2003-09-10
WO2002040030A1 (fr) 2002-05-23
AU2001217709B2 (en) 2005-10-13
JP2004522711A (ja) 2004-07-29
EP1341541A4 (fr) 2004-11-17
WO2002040030A8 (fr) 2002-11-07

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead