CA2425747C - Solid support assay systems and methods utilizing non-standard bases - Google Patents
Solid support assay systems and methods utilizing non-standard bases Download PDFInfo
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- CA2425747C CA2425747C CA2425747A CA2425747A CA2425747C CA 2425747 C CA2425747 C CA 2425747C CA 2425747 A CA2425747 A CA 2425747A CA 2425747 A CA2425747 A CA 2425747A CA 2425747 C CA2425747 C CA 2425747C
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Classifications
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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| US09/861,292 US7422850B2 (en) | 2000-05-19 | 2001-05-18 | Materials and methods for detection of nucleic acids |
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| PCT/US2001/031993 WO2002033126A2 (en) | 2000-10-14 | 2001-10-15 | Solid support assay systems and methods utilizing non-standard bases |
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| US20030194705A1 (en) * | 2002-03-01 | 2003-10-16 | Schroth Gary P. | Methods of using unnatural nucleobases for decoding |
| CA2513626C (en) * | 2003-01-17 | 2013-03-19 | Eragen Biosciences, Inc. | Nucleic acid amplification using non-standard bases |
| US7820808B2 (en) | 2003-04-01 | 2010-10-26 | Eragen Biosciences, Inc. | Polymerase inhibitor and method of using same |
| US7282333B2 (en) * | 2003-10-20 | 2007-10-16 | Promega Corporation | Methods and compositions for nucleic acid analysis |
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2001
- 2001-10-15 EP EP01981538A patent/EP1358352B1/en not_active Expired - Lifetime
- 2001-10-15 DE DE60137649T patent/DE60137649D1/de not_active Expired - Lifetime
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- 2001-10-15 WO PCT/US2001/031993 patent/WO2002033126A2/en not_active Ceased
- 2001-10-15 AU AU1317502A patent/AU1317502A/xx active Pending
- 2001-10-15 AT AT01981538T patent/ATE422557T1/de not_active IP Right Cessation
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| US8217160B2 (en) | 2012-07-10 |
| JP2004531205A (ja) | 2004-10-14 |
| WO2002033126A3 (en) | 2003-08-28 |
| CA2425747A1 (en) | 2002-04-25 |
| US10240189B2 (en) | 2019-03-26 |
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| US20150132759A1 (en) | 2015-05-14 |
| AU2002213175B2 (en) | 2007-09-13 |
| US20040106108A1 (en) | 2004-06-03 |
| US20120295808A1 (en) | 2012-11-22 |
| US8518671B2 (en) | 2013-08-27 |
| EP1358352A2 (en) | 2003-11-05 |
| ATE422557T1 (de) | 2009-02-15 |
| EP1358352B1 (en) | 2009-02-11 |
| US7892796B2 (en) | 2011-02-22 |
| DE60137649D1 (de) | 2009-03-26 |
| JP4499987B2 (ja) | 2010-07-14 |
| US20140024550A1 (en) | 2014-01-23 |
| US6977161B2 (en) | 2005-12-20 |
| US20070087361A1 (en) | 2007-04-19 |
| WO2002033126A2 (en) | 2002-04-25 |
| AU1317502A (en) | 2002-04-29 |
| US20060078936A1 (en) | 2006-04-13 |
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