CA2425368A1 - Nouveaux sulphoxybenzamides - Google Patents
Nouveaux sulphoxybenzamides Download PDFInfo
- Publication number
- CA2425368A1 CA2425368A1 CA002425368A CA2425368A CA2425368A1 CA 2425368 A1 CA2425368 A1 CA 2425368A1 CA 002425368 A CA002425368 A CA 002425368A CA 2425368 A CA2425368 A CA 2425368A CA 2425368 A1 CA2425368 A1 CA 2425368A1
- Authority
- CA
- Canada
- Prior art keywords
- sulphoxybenzamides
- new
- medicaments
- preparing
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C305/00—Esters of sulfuric acids
- C07C305/22—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to carbon atoms of six-membered aromatic rings
- C07C305/24—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to carbon atoms of six-membered aromatic rings of non-condensed six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La présente invention concerne de nouveaux sulfooxybenzamides de la formule (I) dans laquelle Z<0> est un groupe choisi parmi les formules -X<1>-(CH2)r-X<2>- et -CR<4>R<5>- ; A<1> et A<2> sont indépendamment l'un de l'autre des groupes 1,4-phénylène ou 1,3-phénylène éventuellements substitués par un ou plusieurs atomes halogène, des groupes C1-C8-alkyl, des groupes C2-C8-alcényl, des groupes C1-C8-haloalkyl ou des groupes C1-C8-alkoxy, Z<1> et Z<2> sont indépendamment l'un de l'autre un groupe de formule -X<3>-(CH2)8-X<4>- ou une liaison simple ; et, m et n sont indépendamment l'un de l'autre 0 ou 1, les restes R<1>, R<2>, R<3>, R<4>, R<5>, X<1>, X<2>, X<3>, X<4>, r et s ayant la signification donnée dans le descriptif. L'invention concerne également des procédés de fabrication des composés selon l'invention, et leur utilisation en tant qu'agents pharmaceutiques, en particulier en tant qu'antagonistes de leucotriène B4(LTB4).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10052333A DE10052333A1 (de) | 2000-10-24 | 2000-10-24 | Neue Sulfooxybenzamide |
DE10052333.1 | 2000-10-24 | ||
PCT/EP2001/012127 WO2002034715A1 (fr) | 2000-10-24 | 2001-10-19 | Derives benzamidine comportant un groupe sulfate, servant d'antagonistes de ltb4 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2425368A1 true CA2425368A1 (fr) | 2003-04-08 |
CA2425368C CA2425368C (fr) | 2008-12-09 |
Family
ID=7660637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002425368A Expired - Fee Related CA2425368C (fr) | 2000-10-24 | 2001-10-19 | Nouveaux sulphoxybenzamides |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1332128A1 (fr) |
JP (1) | JP3917516B2 (fr) |
AU (1) | AU2002210558A1 (fr) |
CA (1) | CA2425368C (fr) |
DE (1) | DE10052333A1 (fr) |
MX (1) | MXPA03003465A (fr) |
PE (1) | PE20020542A1 (fr) |
WO (1) | WO2002034715A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE481968T1 (de) * | 2004-07-14 | 2010-10-15 | Inflammation Res Ct Company Lt | Verfahren zur hemmung von tumormetastasierung |
ATE460173T1 (de) * | 2005-07-08 | 2010-03-15 | Leopold Franzens Uni Innsbruck | Verwendung von extrakten und inhaltsstoffen aus leontopodium zur steigerung der cholinergen funktion |
CN100402494C (zh) * | 2005-08-25 | 2008-07-16 | 江苏吴中苏药医药开发有限责任公司 | 肌醇硫酸酯铝及其制备方法和口服组合物、应用 |
JP2014515734A (ja) | 2011-03-16 | 2014-07-03 | クリエイティブ セラポーティクス ゲーエムベーハー | 置換ジフェニル誘導体 |
US20200199168A1 (en) | 2017-05-12 | 2020-06-25 | Riken | Class a gpcr-binding compound modifier |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE59309630D1 (de) * | 1992-02-05 | 1999-07-08 | Boehringer Ingelheim Pharma | Neue amidinderivate, ihre herstellung und verwendung als arzneimittel mit ltb4-antagonistischer wirkung |
DE19546452A1 (de) * | 1995-12-13 | 1997-06-19 | Boehringer Ingelheim Kg | Neue Phenylamidinderivate, Verfahren zu ihrer Herstelung und ihre Verwendung als Arzneimittel |
DE19636689A1 (de) * | 1996-09-10 | 1998-03-12 | Boehringer Ingelheim Kg | Neue Benzamidinderivate |
-
2000
- 2000-10-24 DE DE10052333A patent/DE10052333A1/de not_active Withdrawn
-
2001
- 2001-10-19 JP JP2002537708A patent/JP3917516B2/ja not_active Expired - Fee Related
- 2001-10-19 EP EP01978439A patent/EP1332128A1/fr not_active Withdrawn
- 2001-10-19 WO PCT/EP2001/012127 patent/WO2002034715A1/fr active Application Filing
- 2001-10-19 MX MXPA03003465A patent/MXPA03003465A/es unknown
- 2001-10-19 AU AU2002210558A patent/AU2002210558A1/en not_active Abandoned
- 2001-10-19 CA CA002425368A patent/CA2425368C/fr not_active Expired - Fee Related
- 2001-10-22 PE PE2001001045A patent/PE20020542A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1332128A1 (fr) | 2003-08-06 |
DE10052333A1 (de) | 2002-05-02 |
AU2002210558A1 (en) | 2002-05-06 |
CA2425368C (fr) | 2008-12-09 |
PE20020542A1 (es) | 2002-07-16 |
MXPA03003465A (es) | 2004-12-06 |
JP2004512322A (ja) | 2004-04-22 |
WO2002034715A1 (fr) | 2002-05-02 |
JP3917516B2 (ja) | 2007-05-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY134892A (en) | Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and their use | |
WO2001032646A3 (fr) | Nouveaux composes | |
IL160440A (en) | Dihydropteridinones, method for producing the same and the use thereof as medicaments | |
WO2002048147A3 (fr) | Composes therapeutiques | |
CA2450093A1 (fr) | Polymorphe stable de flibanserine, procede de preparation associe et utilisation dudit polymorphe dans la preparation de medicaments | |
WO2003037860A3 (fr) | Analogues de purine presentant une activite inhibitrice de hsp90 | |
WO2003095455A3 (fr) | Composes therapeutiques | |
WO2003016282A3 (fr) | Nouveaux 1h-dihydropyrazoles substitues et leurs procedes de preparation et d'utilisation | |
WO2003006425A3 (fr) | Nouveaux composes convenant comme anti-inflammatoires, immuno-modulateurs et anti-proliferants | |
MXPA03011972A (es) | Arilaminas para tratamiento de condiciones asociadas con gsk-3. | |
WO2002008194A8 (fr) | Derives acridine et utilisation en tant qu'agents pharmaceutiques | |
CA2400268A1 (fr) | Derives de pyrrolopyrimidinone, procedes d'elaboration et d'utilisation | |
CA2378148A1 (fr) | Trifluorobutenes nematicides | |
MXPA02011370A (es) | Iminoazinas substituidas. | |
WO2001082909A3 (fr) | Derives de 2-acyl-indole et leur utilisation comme agents antitumoraux | |
CA2470809A1 (fr) | Derives de 6-aminomorphinane et methode de production et utilisation connexes | |
WO2002010152A3 (fr) | Nouveaux derives d'indol et leur utilisation comme medicaments | |
CA2462998A1 (fr) | Nouveaux composes oestrogeniques | |
CA2356985A1 (fr) | Antagonistes du recepteur 5ht1 pour therapie antidepressive | |
GB0229081D0 (en) | Multifunctional cationic photoinitiators, their preparation and use | |
CA2362217A1 (fr) | Methode de preparation d'intermediaires de pesticide a base de phenylpyrazole | |
WO2001049654A3 (fr) | Derives d'aminomethyle-phenyle-cyclohexane substitues | |
WO2002016322A3 (fr) | Nouveau procede | |
WO2000059862A3 (fr) | Procedes destines a la preparation de produits intermediaires pesticides | |
AU2002248531A1 (en) | Pyrazolopyriadine derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |