CA2421585A1 - Method and composition for treating tumors by selective induction of apoptosis - Google Patents
Method and composition for treating tumors by selective induction of apoptosis Download PDFInfo
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- CA2421585A1 CA2421585A1 CA002421585A CA2421585A CA2421585A1 CA 2421585 A1 CA2421585 A1 CA 2421585A1 CA 002421585 A CA002421585 A CA 002421585A CA 2421585 A CA2421585 A CA 2421585A CA 2421585 A1 CA2421585 A1 CA 2421585A1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US65877900A | 2000-09-11 | 2000-09-11 | |
US09/658,779 | 2000-09-11 | ||
PCT/US2001/028259 WO2002022175A2 (en) | 2000-09-11 | 2001-09-10 | Method and composition for treating tumors by selective induction of apoptosis |
Publications (1)
Publication Number | Publication Date |
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CA2421585A1 true CA2421585A1 (en) | 2002-03-21 |
Family
ID=24642656
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CA002421585A Abandoned CA2421585A1 (en) | 2000-09-11 | 2001-09-10 | Method and composition for treating tumors by selective induction of apoptosis |
Country Status (6)
Country | Link |
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EP (1) | EP1317288A2 (zh) |
JP (1) | JP2004526666A (zh) |
CN (1) | CN1744919A (zh) |
AU (1) | AU2001290720A1 (zh) |
CA (1) | CA2421585A1 (zh) |
WO (1) | WO2002022175A2 (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1621550A1 (en) * | 2004-07-29 | 2006-02-01 | Dompé S.P.A. | Tumor-homing cells engineered to produce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) |
CA2585775C (en) | 2004-10-29 | 2013-10-01 | Musc Foundation For Research Development | Cationic ceramides, and analogs thereof, and their use for preventing or treating cancer |
WO2006050265A2 (en) | 2004-10-29 | 2006-05-11 | Musc Foundation For Research Development | Ceramides and apoptosis-signaling ligand |
CN101144081B (zh) * | 2006-09-14 | 2011-06-22 | 复旦大学 | 核苷酸分子trail及其在制备治疗肿瘤药物中的应用 |
WO2010054223A1 (en) | 2008-11-06 | 2010-05-14 | Musc Foundation For Research Development | Lysosomotropic inhibitors of acid ceramidase |
CN102712933A (zh) * | 2009-11-05 | 2012-10-03 | 西马生物医学计划公司 | 调控的表达系统 |
KR101380840B1 (ko) * | 2010-04-01 | 2014-04-04 | 한국생명공학연구원 | Trail 센서타이저 타겟 유전자인 tip41의 발현 또는 활성 억제제를 함유하는 trail 감수성 증진용 조성물 |
US9428565B2 (en) * | 2011-01-31 | 2016-08-30 | The General Hospital Corporation | Treatment and bioluminescent visualization using multimodal TRAIL molecules |
WO2014018113A1 (en) | 2012-07-24 | 2014-01-30 | The General Hospital Corporation | Oncolytic virus therapy for resistant tumors |
EP2890720B1 (en) | 2012-08-30 | 2019-07-17 | The General Hospital Corporation | Compositions and methods for treating cancer |
JP6785653B2 (ja) | 2013-06-25 | 2020-11-18 | ザ・ウォルター・アンド・エリザ・ホール・インスティテュート・オブ・メディカル・リサーチ | 細胞内感染の処置方法 |
CN105126120B (zh) * | 2015-08-24 | 2018-12-21 | 浙江大学 | 长非编码rna h19与癌症铂类化疗药物耐药相关性 |
EP3464627B1 (en) * | 2016-06-03 | 2020-10-21 | Institut national de recherche pour l'agriculture, l'alimentation et l'environnement | Diet controlled expression of a nucleic acid encoding a pro-apoptotic protein |
US20200248149A1 (en) * | 2017-03-24 | 2020-08-06 | Ohio State Innovation Foundation | Novel recombinant adeno-associated viral vectors restricting off-target transduction in liver and uses thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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US6900185B1 (en) * | 2000-04-12 | 2005-05-31 | University Of Iowa Research Foundation | Method of inducing tumor cell apoptosis using trail/Apo-2 ligand gene transfer |
-
2001
- 2001-09-10 EP EP01970744A patent/EP1317288A2/en not_active Withdrawn
- 2001-09-10 CN CNA018173152A patent/CN1744919A/zh active Pending
- 2001-09-10 CA CA002421585A patent/CA2421585A1/en not_active Abandoned
- 2001-09-10 JP JP2002526423A patent/JP2004526666A/ja active Pending
- 2001-09-10 WO PCT/US2001/028259 patent/WO2002022175A2/en active Search and Examination
- 2001-09-10 AU AU2001290720A patent/AU2001290720A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2004526666A (ja) | 2004-09-02 |
EP1317288A2 (en) | 2003-06-11 |
WO2002022175A3 (en) | 2002-08-08 |
CN1744919A (zh) | 2006-03-08 |
WO2002022175A2 (en) | 2002-03-21 |
AU2001290720A1 (en) | 2002-03-26 |
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