CA2417813A1 - Improved solid pharmaceutical dosage formulation of hydrophobic drugs - Google Patents

Improved solid pharmaceutical dosage formulation of hydrophobic drugs Download PDF

Info

Publication number
CA2417813A1
CA2417813A1 CA002417813A CA2417813A CA2417813A1 CA 2417813 A1 CA2417813 A1 CA 2417813A1 CA 002417813 A CA002417813 A CA 002417813A CA 2417813 A CA2417813 A CA 2417813A CA 2417813 A1 CA2417813 A1 CA 2417813A1
Authority
CA
Canada
Prior art keywords
dosage formulation
deposit
polymer
substrate
formulation according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002417813A
Other languages
English (en)
French (fr)
Inventor
Ramaswamy Murari
Suggy S. Chrai
Jen-Chi Chen
Ashok Katdare
Gregory E. Parry
Marc S. Karetny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delsys Pharmaceutical Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2417813A1 publication Critical patent/CA2417813A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002417813A 2000-08-10 2001-08-09 Improved solid pharmaceutical dosage formulation of hydrophobic drugs Abandoned CA2417813A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22427500P 2000-08-10 2000-08-10
US60/224,275 2000-08-10
PCT/US2001/024949 WO2002013762A2 (en) 2000-08-10 2001-08-09 Improved solid pharmaceutical dosage formulation of hydrophobic drugs

Publications (1)

Publication Number Publication Date
CA2417813A1 true CA2417813A1 (en) 2002-02-21

Family

ID=22839969

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002417813A Abandoned CA2417813A1 (en) 2000-08-10 2001-08-09 Improved solid pharmaceutical dosage formulation of hydrophobic drugs

Country Status (10)

Country Link
US (1) US20020036154A1 (hu)
EP (1) EP1307097A4 (hu)
JP (1) JP2004505996A (hu)
KR (1) KR20030024849A (hu)
CN (1) CN1469707A (hu)
AU (1) AU2001284772A1 (hu)
CA (1) CA2417813A1 (hu)
HU (1) HUP0301668A2 (hu)
IL (1) IL154268A0 (hu)
WO (1) WO2002013762A2 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0114532D0 (en) * 2001-06-14 2001-08-08 Jagotec Ag Novel compositions
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
SI21402A (sl) * 2003-02-12 2004-08-31 LEK farmacevtska dru�ba d.d. Obloženi delci in farmacevtske oblike
WO2005058280A2 (en) * 2003-12-12 2005-06-30 Myogen, Inc. Enoximone formulations and their use in the treatment of cardiac hypertrophy and heart failure
SI1765292T1 (en) 2004-06-12 2018-04-30 Collegium Pharmaceutical, Inc. Formulations of medicines to discourage abuse
DE102004056576A1 (de) * 2004-11-23 2006-05-24 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Rapidcard
WO2008084828A1 (ja) * 2007-01-11 2008-07-17 Kaneka Corporation 補酵素ｑ10粒子の製造方法
KR20080076382A (ko) * 2007-02-15 2008-08-20 (주)아모레퍼시픽 실로스타졸의 제어방출 제제 및 그 제조방법
EP2200613B1 (en) 2007-09-21 2018-09-05 The Johns Hopkins University Phenazine derivatives and uses thereof
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
US11077134B1 (en) * 2020-11-10 2021-08-03 Mountain Valley Md Inc Water dissolvable macrocyclic lactone cyclodextrin complexes
KR20240103309A (ko) * 2022-12-27 2024-07-04 삼육대학교산학협력단 폴리에틸렌글라이콜 기반의 비이온성 계면활성제와 함께 안정화된 소수성약물을 담지한 초음파 감응 마이크로 버블 약물전달체 및 이의 제조방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344934A (en) * 1978-11-20 1982-08-17 American Home Products Corporation Therapeutic compositions with enhanced bioavailability
US4690824A (en) * 1983-07-07 1987-09-01 Redi-Rowell, Inc. Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range
US4640322A (en) * 1985-06-19 1987-02-03 Cozzoli Machine Co. Method and apparatus for filling a receptacle with a material
JPH02180265A (ja) * 1988-12-28 1990-07-13 Nippon Eranko Kk カプセル充填装置
US5046618A (en) * 1990-11-19 1991-09-10 R. P. Scherer Corporation Child-resistant blister pack
IT1242614B (it) * 1990-12-07 1994-05-16 Macofar Spa Macchina per il dosaggio e l'introduzione di prodotti polerulenti in contenitori.
US5343672A (en) * 1992-12-01 1994-09-06 Scherer Ltd R P Method for manufacturing freeze dried dosages in a multilaminate blister pack
US5972383A (en) * 1994-03-02 1999-10-26 Eli Lilly And Company Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
US5811120A (en) * 1994-03-02 1998-09-22 Eli Lilly And Company Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
GB9608719D0 (en) * 1996-04-26 1996-07-03 Scherer Ltd R P Pharmaceutical compositions
FR2748989B1 (fr) * 1996-05-22 1998-08-21 Henaux Claude Procede et dispositif d'ensachage multipoches et sachets ainsi obtenus
US5993858A (en) * 1996-06-14 1999-11-30 Port Systems L.L.C. Method and formulation for increasing the bioavailability of poorly water-soluble drugs
WO1998029141A1 (en) * 1996-12-31 1998-07-09 Inhale Therapeutic Systems, Inc. Processes for spray drying solutions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
CA2282439C (en) * 1997-03-05 2010-05-04 Sugen, Inc. Formulations for hydrophobic pharmaceutical agents
KR20010052734A (ko) * 1998-06-10 2001-06-25 낸시 엠. 그레이 약제학적 제품 및 이의 제조방법 및 제조장치
WO2002003914A2 (en) * 2000-07-06 2002-01-17 Delsys Pharmaceutical Corporation Improved thyroid hormone formulations

Also Published As

Publication number Publication date
EP1307097A4 (en) 2004-01-28
WO2002013762A2 (en) 2002-02-21
AU2001284772A1 (en) 2002-02-25
IL154268A0 (en) 2003-09-17
KR20030024849A (ko) 2003-03-26
HUP0301668A2 (hu) 2003-09-29
CN1469707A (zh) 2004-01-21
WO2002013762A3 (en) 2002-05-16
EP1307097A2 (en) 2003-05-07
JP2004505996A (ja) 2004-02-26
US20020036154A1 (en) 2002-03-28

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Legal Events

Date Code Title Description
FZDE Discontinued