CA2417392C - Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex - Google Patents

Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex Download PDF

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Publication number
CA2417392C
CA2417392C CA002417392A CA2417392A CA2417392C CA 2417392 C CA2417392 C CA 2417392C CA 002417392 A CA002417392 A CA 002417392A CA 2417392 A CA2417392 A CA 2417392A CA 2417392 C CA2417392 C CA 2417392C
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CA
Canada
Prior art keywords
dithiocarbamate
radiopharmaceutical
technetium
diagnostic imaging
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002417392A
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English (en)
French (fr)
Other versions
CA2417392A1 (en
Inventor
Adriano Duatti
Cristina Bolzati
Licia Uccelli
Alessandra Boschi
Fiorenzo Refosco
Francesco Tisato
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Nihon Medi Physics Co Ltd
Original Assignee
Nihon Medi Physics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Medi Physics Co Ltd filed Critical Nihon Medi Physics Co Ltd
Publication of CA2417392A1 publication Critical patent/CA2417392A1/en
Application granted granted Critical
Publication of CA2417392C publication Critical patent/CA2417392C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
CA002417392A 2000-07-28 2001-07-25 Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex Expired - Fee Related CA2417392C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-228898 2000-07-28
JP2000228898 2000-07-28
PCT/JP2001/006402 WO2002009771A1 (en) 2000-07-28 2001-07-25 Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex

Publications (2)

Publication Number Publication Date
CA2417392A1 CA2417392A1 (en) 2002-02-07
CA2417392C true CA2417392C (en) 2007-09-11

Family

ID=18722107

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002417392A Expired - Fee Related CA2417392C (en) 2000-07-28 2001-07-25 Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex

Country Status (14)

Country Link
US (2) US7445765B2 (da)
EP (1) EP1307239B1 (da)
JP (1) JP4338394B2 (da)
KR (1) KR100845449B1 (da)
AT (1) ATE410192T1 (da)
AU (2) AU2001276677B2 (da)
CA (1) CA2417392C (da)
DE (1) DE60136073D1 (da)
DK (1) DK1307239T3 (da)
ES (1) ES2315295T3 (da)
NO (1) NO328931B1 (da)
NZ (1) NZ523663A (da)
TW (1) TWI240634B (da)
WO (1) WO2002009771A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004096735A2 (en) * 2003-05-02 2004-11-11 Kamaluddin Abdur-Rashid Transfer hydrogenation processes and catalysts
EP1654005A4 (en) * 2003-07-24 2011-06-15 Bracco Imaging Spa STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR PREPARATION
JP2008037752A (ja) * 2004-11-19 2008-02-21 Nihon Medi Physics Co Ltd 新規放射性テクネチウム−ビスホスフィノアミン錯体および該錯体を含む放射性画像診断剤
WO2006080993A1 (en) * 2004-12-08 2006-08-03 Purdue Research Foundation Novel cationic metal complex radiopharmaceuticals
AU2006335853B2 (en) 2006-01-20 2011-12-08 Nihon Medi-Physics Co., Ltd. Intermediate compound of technetium nitride complex for radiodiagnostic imaging
CN101020697B (zh) * 2006-11-10 2012-09-05 北京师范大学 一种99mTc、188Re或186Re标记的葡萄糖衍生物配合物及其制备方法
GB0623482D0 (en) 2006-11-24 2007-01-03 Mallinckrodt Inc Technetium-99m (l) tricarbonyl complexes with tridentate chelators for myocardium imaging
CN101066982B (zh) * 2007-03-06 2012-09-05 北京师范大学 氨基酸-葡萄糖衍生物的99mTc配合物及其制备方法
US9021198B1 (en) * 2011-01-20 2015-04-28 Commvault Systems, Inc. System and method for sharing SAN storage
US20130195756A1 (en) 2012-01-31 2013-08-01 General Electric Company 99mTc IMAGING AGENTS AND METHODS OF USE
WO2018109164A1 (en) 2016-12-15 2018-06-21 Bracco Imaging Spa Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds
EP3704082B1 (en) * 2017-12-21 2021-12-15 University of the Free State Multinuclear complexes and their preparation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0403524B1 (fr) 1988-03-09 1993-02-10 Cis Bio International Preparation de complexes nitruro utilisables comme produits radiopharmaceutiques
JP3015970B2 (ja) 1988-11-25 2000-03-06 セ・イ・エス・ビオ・アンテルナショナル・ソシエテ・アノニム 遷移金属の窒化物錯体を含んでいる、心臓への向性を特に有する放射性医薬製品およびその製造方法
FR2664166A1 (fr) 1990-07-04 1992-01-10 Cis Bio Int Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques.
US5162534A (en) * 1990-07-14 1992-11-10 Korea Institute Of Science And Technology Process for the preparation of thiazoline derivatives
FR2679452B1 (fr) 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
DK0949265T3 (da) * 1996-12-18 2003-08-11 Nihon Mediphysics Co Ltd Nitrid-heterokomplekser af radioaktive overgangsmetaller
JP4228355B2 (ja) * 1998-03-19 2009-02-25 テイ・エス テック株式会社 面状弾性体による座面部を有するシート

Also Published As

Publication number Publication date
CA2417392A1 (en) 2002-02-07
EP1307239B1 (en) 2008-10-08
NO20030342D0 (no) 2003-01-23
US20040018147A1 (en) 2004-01-29
WO2002009771A1 (en) 2002-02-07
TWI240634B (en) 2005-10-01
DK1307239T3 (da) 2009-02-09
JP4338394B2 (ja) 2009-10-07
JP2004505064A (ja) 2004-02-19
ES2315295T3 (es) 2009-04-01
EP1307239A4 (en) 2005-01-26
DE60136073D1 (de) 2008-11-20
AU2001276677B2 (en) 2005-10-20
KR20030024809A (ko) 2003-03-26
NZ523663A (en) 2004-06-25
ATE410192T1 (de) 2008-10-15
NO328931B1 (no) 2010-06-21
NO20030342L (no) 2003-03-21
AU7667701A (en) 2002-02-13
US7445765B2 (en) 2008-11-04
US20080267868A1 (en) 2008-10-30
KR100845449B1 (ko) 2008-07-10
EP1307239A1 (en) 2003-05-07

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