CA2417392C - Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex - Google Patents
Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex Download PDFInfo
- Publication number
- CA2417392C CA2417392C CA002417392A CA2417392A CA2417392C CA 2417392 C CA2417392 C CA 2417392C CA 002417392 A CA002417392 A CA 002417392A CA 2417392 A CA2417392 A CA 2417392A CA 2417392 C CA2417392 C CA 2417392C
- Authority
- CA
- Canada
- Prior art keywords
- dithiocarbamate
- radiopharmaceutical
- technetium
- diagnostic imaging
- bis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000-228898 | 2000-07-28 | ||
JP2000228898 | 2000-07-28 | ||
PCT/JP2001/006402 WO2002009771A1 (en) | 2000-07-28 | 2001-07-25 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2417392A1 CA2417392A1 (en) | 2002-02-07 |
CA2417392C true CA2417392C (en) | 2007-09-11 |
Family
ID=18722107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002417392A Expired - Fee Related CA2417392C (en) | 2000-07-28 | 2001-07-25 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex |
Country Status (14)
Country | Link |
---|---|
US (2) | US7445765B2 (da) |
EP (1) | EP1307239B1 (da) |
JP (1) | JP4338394B2 (da) |
KR (1) | KR100845449B1 (da) |
AT (1) | ATE410192T1 (da) |
AU (2) | AU2001276677B2 (da) |
CA (1) | CA2417392C (da) |
DE (1) | DE60136073D1 (da) |
DK (1) | DK1307239T3 (da) |
ES (1) | ES2315295T3 (da) |
NO (1) | NO328931B1 (da) |
NZ (1) | NZ523663A (da) |
TW (1) | TWI240634B (da) |
WO (1) | WO2002009771A1 (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004096735A2 (en) * | 2003-05-02 | 2004-11-11 | Kamaluddin Abdur-Rashid | Transfer hydrogenation processes and catalysts |
EP1654005A4 (en) * | 2003-07-24 | 2011-06-15 | Bracco Imaging Spa | STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR PREPARATION |
JP2008037752A (ja) * | 2004-11-19 | 2008-02-21 | Nihon Medi Physics Co Ltd | 新規放射性テクネチウム−ビスホスフィノアミン錯体および該錯体を含む放射性画像診断剤 |
WO2006080993A1 (en) * | 2004-12-08 | 2006-08-03 | Purdue Research Foundation | Novel cationic metal complex radiopharmaceuticals |
AU2006335853B2 (en) | 2006-01-20 | 2011-12-08 | Nihon Medi-Physics Co., Ltd. | Intermediate compound of technetium nitride complex for radiodiagnostic imaging |
CN101020697B (zh) * | 2006-11-10 | 2012-09-05 | 北京师范大学 | 一种99mTc、188Re或186Re标记的葡萄糖衍生物配合物及其制备方法 |
GB0623482D0 (en) | 2006-11-24 | 2007-01-03 | Mallinckrodt Inc | Technetium-99m (l) tricarbonyl complexes with tridentate chelators for myocardium imaging |
CN101066982B (zh) * | 2007-03-06 | 2012-09-05 | 北京师范大学 | 氨基酸-葡萄糖衍生物的99mTc配合物及其制备方法 |
US9021198B1 (en) * | 2011-01-20 | 2015-04-28 | Commvault Systems, Inc. | System and method for sharing SAN storage |
US20130195756A1 (en) | 2012-01-31 | 2013-08-01 | General Electric Company | 99mTc IMAGING AGENTS AND METHODS OF USE |
WO2018109164A1 (en) | 2016-12-15 | 2018-06-21 | Bracco Imaging Spa | Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds |
EP3704082B1 (en) * | 2017-12-21 | 2021-12-15 | University of the Free State | Multinuclear complexes and their preparation |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0403524B1 (fr) | 1988-03-09 | 1993-02-10 | Cis Bio International | Preparation de complexes nitruro utilisables comme produits radiopharmaceutiques |
JP3015970B2 (ja) | 1988-11-25 | 2000-03-06 | セ・イ・エス・ビオ・アンテルナショナル・ソシエテ・アノニム | 遷移金属の窒化物錯体を含んでいる、心臓への向性を特に有する放射性医薬製品およびその製造方法 |
FR2664166A1 (fr) | 1990-07-04 | 1992-01-10 | Cis Bio Int | Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques. |
US5162534A (en) * | 1990-07-14 | 1992-11-10 | Korea Institute Of Science And Technology | Process for the preparation of thiazoline derivatives |
FR2679452B1 (fr) | 1991-07-22 | 1993-11-12 | Cis Bio International | Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation. |
DK0949265T3 (da) * | 1996-12-18 | 2003-08-11 | Nihon Mediphysics Co Ltd | Nitrid-heterokomplekser af radioaktive overgangsmetaller |
JP4228355B2 (ja) * | 1998-03-19 | 2009-02-25 | テイ・エス テック株式会社 | 面状弾性体による座面部を有するシート |
-
2001
- 2001-07-25 AU AU2001276677A patent/AU2001276677B2/en not_active Ceased
- 2001-07-25 ES ES01954337T patent/ES2315295T3/es not_active Expired - Lifetime
- 2001-07-25 CA CA002417392A patent/CA2417392C/en not_active Expired - Fee Related
- 2001-07-25 WO PCT/JP2001/006402 patent/WO2002009771A1/en active IP Right Grant
- 2001-07-25 AT AT01954337T patent/ATE410192T1/de not_active IP Right Cessation
- 2001-07-25 JP JP2002515323A patent/JP4338394B2/ja not_active Expired - Fee Related
- 2001-07-25 DE DE60136073T patent/DE60136073D1/de not_active Expired - Lifetime
- 2001-07-25 EP EP01954337A patent/EP1307239B1/en not_active Expired - Lifetime
- 2001-07-25 NZ NZ523663A patent/NZ523663A/en not_active IP Right Cessation
- 2001-07-25 DK DK01954337T patent/DK1307239T3/da active
- 2001-07-25 AU AU7667701A patent/AU7667701A/xx active Pending
- 2001-07-25 KR KR1020037001096A patent/KR100845449B1/ko not_active IP Right Cessation
- 2001-07-25 US US10/332,707 patent/US7445765B2/en not_active Expired - Fee Related
- 2001-07-27 TW TW090118475A patent/TWI240634B/zh not_active IP Right Cessation
-
2003
- 2003-01-23 NO NO20030342A patent/NO328931B1/no not_active IP Right Cessation
-
2007
- 2007-08-09 US US11/889,127 patent/US20080267868A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2417392A1 (en) | 2002-02-07 |
EP1307239B1 (en) | 2008-10-08 |
NO20030342D0 (no) | 2003-01-23 |
US20040018147A1 (en) | 2004-01-29 |
WO2002009771A1 (en) | 2002-02-07 |
TWI240634B (en) | 2005-10-01 |
DK1307239T3 (da) | 2009-02-09 |
JP4338394B2 (ja) | 2009-10-07 |
JP2004505064A (ja) | 2004-02-19 |
ES2315295T3 (es) | 2009-04-01 |
EP1307239A4 (en) | 2005-01-26 |
DE60136073D1 (de) | 2008-11-20 |
AU2001276677B2 (en) | 2005-10-20 |
KR20030024809A (ko) | 2003-03-26 |
NZ523663A (en) | 2004-06-25 |
ATE410192T1 (de) | 2008-10-15 |
NO328931B1 (no) | 2010-06-21 |
NO20030342L (no) | 2003-03-21 |
AU7667701A (en) | 2002-02-13 |
US7445765B2 (en) | 2008-11-04 |
US20080267868A1 (en) | 2008-10-30 |
KR100845449B1 (ko) | 2008-07-10 |
EP1307239A1 (en) | 2003-05-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2417392C (en) | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | |
US5300278A (en) | Process for the preparation of 99m Tc, 186 Re or 188 Re nitride complexes usable as radiopharmaceutical products | |
Boschi et al. | High-yield synthesis of the terminal 188Re≡ N multiple bond from generator-produced [188ReO4]− | |
JP3097755B2 (ja) | 遷移金属の窒化物錯体の製造方法 | |
US5288476A (en) | Radiopharmaceutical product more particularly having a cardiac tropism incorporating a nitride complex of a transition metal and its preparation process | |
Luo et al. | Rhenium (V) and technetium (V) complexes of bidentate (O, O) monobasic 3-oxy-4-pyronato and-4-pyridinonato ligands. X-ray structures of cis-bromobis (3-methyl-2-oxy-4-pyronato) oxorhenium (V), tetra-n-butylammonium tribromo (3-methyl-2-oxy-4-pyronato) oxorhenate (V), and tetra-n-butylammonium trichloro (3-methyl-2-oxy-4-pyronato) oxotechnetate (V) | |
AU2001276677A1 (en) | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | |
EP0441953B1 (en) | New cores for technetium radiopharmaceuticals | |
Baldas et al. | Effect of the Tc-nitrido group on the behaviour of 99mTc-radiopharmaceuticals | |
US4885100A (en) | Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes | |
US5420321A (en) | Tris(isonitrile)copper(i) sulfates for preparing radionuclide complexes | |
US5081232A (en) | Complexes of tc99m radiopharmaceuticals | |
Cattabriga et al. | Synthesis and structural characterization of technetium and rhenium complexes containing derivatized amino acids | |
Cox | The Chemistry and Pharmacy of Ida-Derivatives | |
Zmbova et al. | Synthesis and quality control of 99mTc-p-butyl IDA | |
Nock et al. | Reaction with glutathione. A possible mechanism involved in rodent brain retention of a {sup 99m} Tc SNS/S complex containing a pendant ester functionality | |
Johannsen | Advances in Radiochemistry of Tc99m | |
Luo | Chelate complexes of rhenium and technetium: toward their potential applications as radiopharmaceuticals | |
NZ314409A (en) | Preparation of a coordination complex of an isonitrile ligand and a radionuclide (typically technetium (tc)) by replacing copper in a sulphate complex |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20150727 |