CA2408293A1 - Nouveaux derives antagonistes du recepteur de la vitronectine - Google Patents
Nouveaux derives antagonistes du recepteur de la vitronectine Download PDFInfo
- Publication number
- CA2408293A1 CA2408293A1 CA002408293A CA2408293A CA2408293A1 CA 2408293 A1 CA2408293 A1 CA 2408293A1 CA 002408293 A CA002408293 A CA 002408293A CA 2408293 A CA2408293 A CA 2408293A CA 2408293 A1 CA2408293 A1 CA 2408293A1
- Authority
- CA
- Canada
- Prior art keywords
- amino
- tetrahydro
- oxo
- pyrimidinyl
- tyrosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0005859A FR2808798A1 (fr) | 2000-05-09 | 2000-05-09 | Nouveaux derives antagonistes du recepteur de la vitronectine |
| FR00/05859 | 2000-05-09 | ||
| PCT/FR2001/001357 WO2001085729A1 (fr) | 2000-05-09 | 2001-05-04 | Nouveaux derives antagonistes du recepteur de la vitronectine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2408293A1 true CA2408293A1 (fr) | 2001-11-15 |
Family
ID=8850000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002408293A Abandoned CA2408293A1 (fr) | 2000-05-09 | 2001-05-04 | Nouveaux derives antagonistes du recepteur de la vitronectine |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6838453B2 (OSRAM) |
| EP (1) | EP1282621B1 (OSRAM) |
| JP (1) | JP5143989B2 (OSRAM) |
| AT (1) | ATE304012T1 (OSRAM) |
| AU (1) | AU2001258489A1 (OSRAM) |
| CA (1) | CA2408293A1 (OSRAM) |
| DE (1) | DE60113248T2 (OSRAM) |
| ES (1) | ES2249431T3 (OSRAM) |
| FR (1) | FR2808798A1 (OSRAM) |
| IL (1) | IL152613A0 (OSRAM) |
| MX (1) | MXPA02011043A (OSRAM) |
| WO (1) | WO2001085729A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3332679B2 (ja) | 1995-08-08 | 2002-10-07 | 昭和電工株式会社 | 押継ぎ押出用ダイス |
| PL371841A1 (pl) | 2004-12-20 | 2006-06-26 | ADAMED Sp.z o.o. | Nowe związki pochodne kwasu 3-fenylopropionowego |
| PL372332A1 (pl) * | 2005-01-19 | 2006-07-24 | ADAMED Sp.z o.o. | Nowe związki, pochodne kwasu 3-fenylopropionowego |
| PL372356A1 (pl) * | 2005-01-20 | 2006-07-24 | ADAMED Sp.z o.o. | Nowe związki, pochodne kwasu 3-fenylopropionowego |
| MX2019000043A (es) | 2016-07-05 | 2019-07-04 | Univ Rockefeller | Antagonistas de integrina de tetrahidronaftiridinpentanamida. |
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|---|---|---|---|---|
| US5296486A (en) * | 1991-09-24 | 1994-03-22 | Boehringer Ingelheim Pharmaceuticals, Inc. | Leukotriene biosynthesis inhibitors |
| GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| DE19629816A1 (de) * | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| DE19629817A1 (de) * | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| EP0933367A1 (en) * | 1997-12-19 | 1999-08-04 | Hoechst Marion Roussel Deutschland GmbH | Novel acylguanidine derivates as inhibitors of bone resorption and as vitronectin receptor antagonists |
| JP2002501054A (ja) * | 1998-01-23 | 2002-01-15 | アヴェンティス ファルマ ドイチェラント ゲーエムベーハー | 骨吸収の阻害剤として及び細胞接着の阻害剤としての新規のスルホンアミド誘導体 |
| DZ2741A1 (fr) * | 1998-03-10 | 2003-09-08 | Smithkline Beecham Corp | Composés nouveaux antagonistes des récepteurs de vitronectine procédé pour leur préparation et compositions. |
| ATE253061T1 (de) * | 1998-06-29 | 2003-11-15 | Iaf Biochem Int | Zur behandlung von krebs nützliche thiophen- und furan-2,5-dicarboxamide |
| US6630488B1 (en) * | 1998-09-21 | 2003-10-07 | Biochem Pharma, Inc. | Quinolizinones as integrin inhibitors |
| GB9821061D0 (en) * | 1998-09-28 | 1998-11-18 | Celltech Therapeutics Ltd | Chemical compounds |
-
2000
- 2000-05-09 FR FR0005859A patent/FR2808798A1/fr active Pending
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2001
- 2001-05-04 AT AT01931789T patent/ATE304012T1/de not_active IP Right Cessation
- 2001-05-04 IL IL15261301A patent/IL152613A0/xx unknown
- 2001-05-04 MX MXPA02011043A patent/MXPA02011043A/es unknown
- 2001-05-04 EP EP01931789A patent/EP1282621B1/fr not_active Expired - Lifetime
- 2001-05-04 WO PCT/FR2001/001357 patent/WO2001085729A1/fr not_active Ceased
- 2001-05-04 DE DE60113248T patent/DE60113248T2/de not_active Expired - Lifetime
- 2001-05-04 JP JP2001582330A patent/JP5143989B2/ja not_active Expired - Fee Related
- 2001-05-04 AU AU2001258489A patent/AU2001258489A1/en not_active Abandoned
- 2001-05-04 CA CA002408293A patent/CA2408293A1/fr not_active Abandoned
- 2001-05-04 ES ES01931789T patent/ES2249431T3/es not_active Expired - Lifetime
- 2001-05-04 US US10/275,409 patent/US6838453B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2249431T3 (es) | 2006-04-01 |
| DE60113248D1 (de) | 2005-10-13 |
| WO2001085729A1 (fr) | 2001-11-15 |
| JP5143989B2 (ja) | 2013-02-13 |
| JP2003532732A (ja) | 2003-11-05 |
| US6838453B2 (en) | 2005-01-04 |
| US20040225111A1 (en) | 2004-11-11 |
| EP1282621A1 (fr) | 2003-02-12 |
| AU2001258489A1 (en) | 2001-11-20 |
| FR2808798A1 (fr) | 2001-11-16 |
| MXPA02011043A (es) | 2003-03-10 |
| EP1282621B1 (fr) | 2005-09-07 |
| IL152613A0 (en) | 2003-06-24 |
| ATE304012T1 (de) | 2005-09-15 |
| DE60113248T2 (de) | 2006-06-29 |
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