CA2405104A1 - Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides - Google Patents
Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides Download PDFInfo
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- CA2405104A1 CA2405104A1 CA002405104A CA2405104A CA2405104A1 CA 2405104 A1 CA2405104 A1 CA 2405104A1 CA 002405104 A CA002405104 A CA 002405104A CA 2405104 A CA2405104 A CA 2405104A CA 2405104 A1 CA2405104 A1 CA 2405104A1
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- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 1
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- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000005185 salting out Methods 0.000 description 1
- 238000013341 scale-up Methods 0.000 description 1
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- 230000003584 silencer Effects 0.000 description 1
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- 150000003384 small molecules Chemical class 0.000 description 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 1
- 229940048086 sodium pyrophosphate Drugs 0.000 description 1
- 229940054269 sodium pyruvate Drugs 0.000 description 1
- 229960001471 sodium selenite Drugs 0.000 description 1
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- 235000015921 sodium selenite Nutrition 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
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- 239000002904 solvent Substances 0.000 description 1
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- 230000000392 somatic effect Effects 0.000 description 1
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- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
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- 238000011200 topical administration Methods 0.000 description 1
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- 230000002463 transducing effect Effects 0.000 description 1
- 239000012581 transferrin Substances 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 230000010474 transient expression Effects 0.000 description 1
- 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 description 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
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- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
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- 239000004474 valine Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000037314 wound repair Effects 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54377400A | 2000-04-05 | 2000-04-05 | |
| US09/543,774 | 2000-04-05 | ||
| US21573300P | 2000-06-28 | 2000-06-28 | |
| US60/215,733 | 2000-06-28 | ||
| US75756201A | 2001-01-09 | 2001-01-09 | |
| US09/757,562 | 2001-01-09 | ||
| US26661401P | 2001-02-05 | 2001-02-05 | |
| US60/266,614 | 2001-02-05 | ||
| PCT/US2001/011208 WO2001077169A2 (en) | 2000-04-05 | 2001-04-05 | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2405104A1 true CA2405104A1 (en) | 2001-10-18 |
Family
ID=27499020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002405104A Abandoned CA2405104A1 (en) | 2000-04-05 | 2001-04-05 | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1268543A2 (enExample) |
| JP (1) | JP2003530124A (enExample) |
| AU (1) | AU5904101A (enExample) |
| CA (1) | CA2405104A1 (enExample) |
| WO (1) | WO2001077169A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7411052B2 (en) | 2001-03-05 | 2008-08-12 | Nuvelo, Inc. | Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides |
| CA2462795A1 (en) * | 2001-10-03 | 2003-04-10 | Incyte Genomics, Inc. | Secreted proteins |
| PL2157192T3 (pl) | 2003-10-10 | 2014-01-31 | Deutsches Krebsforsch | Kompozycje do diagnozowania i terapii chorób związanych z nieprawidłową ekspresją futrin (R-spondin) |
| AU2005208945A1 (en) * | 2004-01-27 | 2005-08-11 | Kyowa Hakko Kirin Co., Ltd. | Gastrointestinal proliferative factor and uses thereof |
| WO2007030290A2 (en) * | 2005-09-07 | 2007-03-15 | Maine Medical Center Research | Cristin/r-spondin ligands active in the wnt signaling pathway and methods, compositions and kits relating thereto |
| JP2009511017A (ja) * | 2005-10-07 | 2009-03-19 | ヌベロ インコーポレーティッド | 幹細胞因子様タンパク質ｓｃｆａ１及びその使用 |
| EA018260B1 (ru) | 2006-09-29 | 2013-06-28 | Онкомед Фармасьютикалз, Инк. | Антитела к дельта-подобному лиганду 4 человека и их применение |
| WO2008046649A1 (en) | 2006-10-20 | 2008-04-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Rspondins as modulators of angiogenesis and vasculogenesis |
| WO2008075796A1 (ja) * | 2006-12-21 | 2008-06-26 | Kyowa Hakko Kirin Co., Ltd. | 血球回復促進剤 |
| EP3424529A1 (en) | 2007-07-02 | 2019-01-09 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for treating and diagnosing cancer |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| EP3061808B1 (en) | 2009-02-03 | 2020-08-12 | Koninklijke Nederlandse Akademie van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising said stem cells |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| US20120039912A1 (en) | 2009-04-15 | 2012-02-16 | Galapagos Sasu | Rspondin-3 inhibition in bone disorders |
| US8551479B2 (en) | 2010-09-10 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| CN106167526A (zh) | 2011-07-15 | 2016-11-30 | 昂考梅德药品有限公司 | Rspo结合剂和其应用 |
| CN104349785A (zh) * | 2012-03-21 | 2015-02-11 | 达纳-法伯癌症研究所有限公司 | 人淋巴系器官源性抑制性基质细胞的分离和用途 |
| KR20150036603A (ko) | 2012-07-13 | 2015-04-07 | 온코메드 파마슈티칼스, 인크. | Rspo3 결합제 및 그의 용도 |
| TW201628648A (zh) | 2014-09-16 | 2016-08-16 | 安可美德藥物股份有限公司 | 纖維變性疾病之治療 |
| CN108607101A (zh) * | 2018-05-04 | 2018-10-02 | 广西中医药大学附属瑞康医院 | Zip1基因在制备抑制骨髓间充质干细胞凋亡的产品中的应用 |
| CN111420034A (zh) * | 2019-01-08 | 2020-07-17 | 上海莱馥医疗科技有限公司 | 一种用于治疗银屑病的混合干细胞制剂及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001527403A (ja) * | 1997-04-25 | 2001-12-25 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
| WO2000056755A1 (en) * | 1999-03-19 | 2000-09-28 | Human Genome Sciences, Inc. | 49 human secreted proteins |
| CN1297930A (zh) * | 1999-11-29 | 2001-06-06 | 上海博容基因开发有限公司 | 一种新的多肽——人凝血栓蛋白30和编码这种多肽的多核苷酸 |
| AU2001234944A1 (en) * | 2000-02-03 | 2001-08-14 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
-
2001
- 2001-04-05 JP JP2001575639A patent/JP2003530124A/ja not_active Withdrawn
- 2001-04-05 WO PCT/US2001/011208 patent/WO2001077169A2/en not_active Ceased
- 2001-04-05 CA CA002405104A patent/CA2405104A1/en not_active Abandoned
- 2001-04-05 AU AU5904101A patent/AU5904101A/xx active Pending
- 2001-04-05 EP EP01932523A patent/EP1268543A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1268543A2 (en) | 2003-01-02 |
| WO2001077169A2 (en) | 2001-10-18 |
| JP2003530124A (ja) | 2003-10-14 |
| WO2001077169A3 (en) | 2002-07-04 |
| WO2001077169A9 (en) | 2002-12-19 |
| AU5904101A (en) | 2001-10-23 |
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