CA2404858A1 - Treatment of neurodegenerative disease - Google Patents
Treatment of neurodegenerative disease Download PDFInfo
- Publication number
- CA2404858A1 CA2404858A1 CA002404858A CA2404858A CA2404858A1 CA 2404858 A1 CA2404858 A1 CA 2404858A1 CA 002404858 A CA002404858 A CA 002404858A CA 2404858 A CA2404858 A CA 2404858A CA 2404858 A1 CA2404858 A1 CA 2404858A1
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- CA
- Canada
- Prior art keywords
- kit
- group
- drug
- treatment
- disease
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19649700P | 2000-04-12 | 2000-04-12 | |
| US60/196,497 | 2000-04-12 | ||
| US21422100P | 2000-06-23 | 2000-06-23 | |
| US60/214,221 | 2000-06-23 | ||
| US24889000P | 2000-11-15 | 2000-11-15 | |
| US60/248,890 | 2000-11-15 | ||
| PCT/US2001/012484 WO2001078709A2 (en) | 2000-04-12 | 2001-04-12 | Treatment of neurodegenerative disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2404858A1 true CA2404858A1 (en) | 2001-10-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002404858A Abandoned CA2404858A1 (en) | 2000-04-12 | 2001-04-12 | Treatment of neurodegenerative disease |
Country Status (6)
| Country | Link |
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| US (1) | US20030060487A1 (enExample) |
| EP (1) | EP1328261A2 (enExample) |
| JP (1) | JP2003530432A (enExample) |
| AU (1) | AU2001253597A1 (enExample) |
| CA (1) | CA2404858A1 (enExample) |
| WO (1) | WO2001078709A2 (enExample) |
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| US20050148101A1 (en) * | 1999-01-23 | 2005-07-07 | Bamdad Cynthia C. | Interaction of colloid-immobilized species with species on non-colloidal structures |
| CA2424119A1 (en) | 2000-10-03 | 2002-04-11 | Cynthia C. Bamdad | Electronic detection of interaction and detection of interaction based on the interruption of flow |
| US7054758B2 (en) * | 2001-01-30 | 2006-05-30 | Sciona Limited | Computer-assisted means for assessing lifestyle risk factors |
| US20040096880A1 (en) * | 2001-08-07 | 2004-05-20 | Kmiec Eric B. | Compositions and methods for the treatment of diseases exhibiting protein misassembly and aggregation |
| EP1423537A4 (en) * | 2001-08-07 | 2006-11-29 | Univ Delaware | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING HUNTINGTON'S DISEASE |
| FR2828693B1 (fr) † | 2001-08-14 | 2004-06-18 | Exonhit Therapeutics Sa | Nouvelle cible moleculaire de la neurotoxicite |
| DE60236605D1 (de) | 2001-09-05 | 2010-07-15 | Minerva Biotechnologies Corp | Zusammensetzungen und deren verwendung zur behandlung von krebs |
| US20060280730A1 (en) * | 2001-10-12 | 2006-12-14 | Cedars-Sinai Medical Center | Induction of apoptosis of malignant cells by activation of calcium-activated potassium channels |
| WO2004059347A2 (en) | 2002-12-20 | 2004-07-15 | Minerva Biotechnologies Corporation | Optical devices and methods involving nanoparticles |
| ATE333881T1 (de) * | 2003-04-25 | 2006-08-15 | Neuro3D | Verwendung von piperazin- phenothiazin- derivaten zur herstellung eines arzneimittels mit neuroprotektiven und/oder neurotropischen wirkungen auf das zns und/oder pns |
| FR2856595B1 (fr) * | 2003-06-27 | 2008-05-30 | Exonhit Therapeutics Sa | Methodes et compositions pour le traitement de deficits cognitifs. |
| US20050059744A1 (en) * | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
| JP5281794B2 (ja) | 2005-10-25 | 2013-09-04 | 塩野義製薬株式会社 | アミノジヒドロチアジン誘導体 |
| WO2007120972A2 (en) * | 2006-02-10 | 2007-10-25 | University Of Virginia Patent Foundation | Method to treat sickle cell disease |
| WO2007097707A1 (en) * | 2006-02-24 | 2007-08-30 | Axelar Ab | Use of cyclolignans for the treatment of type 2 diabetes and as contraceptives |
| EP2147914B1 (en) | 2007-04-24 | 2014-06-04 | Shionogi&Co., Ltd. | Aminodihydrothiazine derivatives substituted with cyclic groups |
| EP2151435A4 (en) | 2007-04-24 | 2011-09-14 | Shionogi & Co | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
| WO2009005469A2 (en) * | 2007-07-03 | 2009-01-08 | David Erlinge | The use of compounds such as pyridoxal derivatives for the treatment of diabetes or diseases associated with the metabolic syndrome |
| JP5490692B2 (ja) | 2008-06-13 | 2014-05-14 | 塩野義製薬株式会社 | βセクレターゼ阻害作用を有する含硫黄複素環誘導体 |
| WO2010047372A1 (ja) | 2008-10-22 | 2010-04-29 | 塩野義製薬株式会社 | Bace1阻害活性を有する2-アミノピリミジン-4-オンおよび2-アミノピリジン誘導体 |
| UA110467C2 (uk) | 2009-12-11 | 2016-01-12 | Шионогі Енд Ко., Лтд. | Похідні оксазину |
| KR101351181B1 (ko) * | 2010-05-11 | 2014-01-14 | 가천대학교 산학협력단 | 단핵식세포계 세포 내에서 age-알부민의 합성 저해 또는 분비 저해에 의한 세포사 유도 저해 방법 |
| US20120101167A1 (en) | 2010-10-25 | 2012-04-26 | Langham Maurice E | Treatment of ocular and cerebral ischemia |
| EP2634188A4 (en) | 2010-10-29 | 2014-05-07 | Shionogi & Co | FUSIONED AMINODIHYDROPYRIMIDINE DERIVATIVE |
| EP2634186A4 (en) | 2010-10-29 | 2014-03-26 | Shionogi & Co | naphthyridine |
| CN103608345A (zh) | 2011-04-26 | 2014-02-26 | 盐野义制药株式会社 | 噁嗪衍生物和含有该噁嗪衍生物的bace1抑制剂 |
| US20140249180A1 (en) * | 2011-10-03 | 2014-09-04 | National Center For Geriatrics And Gerontology | Tau aggregation inhibitor |
| CN102381991A (zh) * | 2011-10-22 | 2012-03-21 | 杭州福斯特药业有限公司 | 一种章胺盐酸盐的合成方法 |
| EP2830620A4 (en) * | 2012-03-26 | 2015-12-09 | Univ Columbia | 4-AMINOPYRIDINE AS A THERAPEUTIC AGENT FOR SPINAL MUSCLE ATROPHY |
| JP2016501827A (ja) | 2012-10-24 | 2016-01-21 | 塩野義製薬株式会社 | Bace1阻害作用を有するジヒドロオキサジンまたはオキサゼピン誘導体 |
| JP6313750B2 (ja) | 2013-04-02 | 2018-04-18 | 学校法人同志社 | タウ凝集阻害剤 |
| EP3019865A4 (en) * | 2013-07-12 | 2017-04-05 | Immuneering Corporation | Systems, methods, and environment for automated review of genomic data to identify downregulated and/or upregulated gene expression indicative of a disease or condition |
| US11648212B2 (en) * | 2016-02-03 | 2023-05-16 | Intelgenx Corp. | Loxapine film oral dosage form |
| US11173144B2 (en) | 2016-05-13 | 2021-11-16 | The Board Of Trustees Of The Leland Stanford Junior University | Adrenergic receptor modulating compounds and methods of using the same |
| US20230395255A1 (en) * | 2020-10-22 | 2023-12-07 | Icahn School Of Medicine At Mount Sinai | Methods for identifying and targeting the molecular subtypes of alzheimer's disease |
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| US5525727A (en) * | 1982-05-18 | 1996-06-11 | University Of Florida | Brain-specific drug delivery |
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| US4452775A (en) * | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| CA1200416A (en) * | 1983-05-13 | 1986-02-11 | Societe Des Produits Nestle S.A. | Food process |
| US5075109A (en) * | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| EP0311313B1 (en) * | 1987-10-05 | 1995-05-10 | Yamanouchi Pharmaceutical Co. Ltd. | Heterocyclic spiro compounds and their preparation |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
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| JPH04167172A (ja) * | 1990-10-31 | 1992-06-15 | Nec Corp | ベクトルプロセッサ |
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| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
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| US5962463A (en) * | 1992-10-09 | 1999-10-05 | Massachusetts Institute Of Technology | Methods of stimulating non-amyloidogenic processing of the amyloid precursor protein |
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| IL112567A (en) * | 1994-02-10 | 2000-02-29 | Wyeth John & Brother Ltd | Substituted quinolines their preparation and pharmaceutical compositions containing them |
| US5620850A (en) * | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
| US5605911A (en) * | 1995-01-31 | 1997-02-25 | Washington University | Use of alpha-2 adrenergic drugs to prevent adverse effects of NMDA receptor hypofunction (NRH) |
| US5736152A (en) * | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| US6255347B1 (en) * | 1996-06-21 | 2001-07-03 | Advanced Research And Technology Institute | Methods and compositions comprising R-ibuprofen |
| WO1998007431A1 (en) * | 1996-08-22 | 1998-02-26 | New York University | Cholinesterase inhibitors for treatment of parkinson's disease |
| HUP9903557A2 (en) * | 1996-08-29 | 2002-08-28 | Takeda Chemical Industries Ltd | Cyclic ether compounds, producing and useing them |
| US6184248B1 (en) * | 1996-09-05 | 2001-02-06 | Robert K. K. Lee | Compositions and methods for treatment of neurological disorders and neurodegenerative diseases |
| JP4427639B2 (ja) * | 1996-12-12 | 2010-03-10 | イスム リサーチ ディベロップメント カンパニー オブ ザ ヘブライ ユニバーシティ オブ エルサレム | 合成アンチセンスオリゴデオキシヌクレオチド類およびそれらを含む医薬組成物 |
| FR2757161B1 (fr) * | 1996-12-13 | 1999-03-12 | Sanofi Sa | Diphenylalkyl-tetrahydropyridines |
| AU5727798A (en) * | 1996-12-23 | 1998-07-17 | Texas A & M University, The | Anti-amyloidogenic agents |
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| US6514686B2 (en) * | 1997-04-28 | 2003-02-04 | The University Of British Columbia | Method and composition for modulating amyloidosis |
| JP2002504895A (ja) * | 1997-04-28 | 2002-02-12 | ザ ユニバーシティー オブ ブリティッシュコロンビア | アミロイド症を調節する方法及び組成 |
| ZA985765B (en) * | 1997-07-02 | 1999-08-04 | Merck & Co Inc | Polymorphic form of a tachykinin receptor antagonist. |
| US6136559A (en) * | 1998-10-07 | 2000-10-24 | Ortho Pharmaceutical Corporation | DNA encoding as human histamine receptor of the H3 subtype |
| US6586475B1 (en) * | 1998-11-20 | 2003-07-01 | Takeda Chemical Industries, Ltd. | β-amyloid protein production/secretion inhibitors |
| EP1132372A3 (en) * | 2000-03-06 | 2003-11-19 | Solvias AG | Bicyclic 1,3-aminoalcohols, d8-metal complexes and hydrogenation processes |
| CA2424119A1 (en) * | 2000-10-03 | 2002-04-11 | Cynthia C. Bamdad | Electronic detection of interaction and detection of interaction based on the interruption of flow |
| WO2002039999A2 (en) * | 2000-11-15 | 2002-05-23 | Minerva Biotechnologies Corporation | Use of suramine, l-histidine, quisqualic acid or d-cycloserine for angiogenesis inhibition |
| CA2428732C (en) * | 2000-11-15 | 2018-07-31 | Minerva Biotechnologies Corporation | Methods and kit for simultaneous screening of interactions between a plurality of chemical or biological species and uses thereof |
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- 2001-04-12 US US09/835,099 patent/US20030060487A1/en not_active Abandoned
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| US20030060487A1 (en) | 2003-03-27 |
| EP1328261A2 (en) | 2003-07-23 |
| WO2001078709A2 (en) | 2001-10-25 |
| WO2001078709A3 (en) | 2003-04-17 |
| AU2001253597A1 (en) | 2001-10-30 |
| JP2003530432A (ja) | 2003-10-14 |
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