JP2003530432A - 神経変性疾患の治療 - Google Patents

神経変性疾患の治療

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Publication number
JP2003530432A
JP2003530432A JP2001576010A JP2001576010A JP2003530432A JP 2003530432 A JP2003530432 A JP 2003530432A JP 2001576010 A JP2001576010 A JP 2001576010A JP 2001576010 A JP2001576010 A JP 2001576010A JP 2003530432 A JP2003530432 A JP 2003530432A
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Japan
Prior art keywords
kit
disease
group
treatment
ring
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Pending
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JP2001576010A
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English (en)
Japanese (ja)
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JP2003530432A5 (enExample
Inventor
バムダッド，アール・ショシャナ
バムダッド，シンシア・シー
Original Assignee
ミナーヴァ・バイオテクノロジーズ・コーポレーション
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Publication of JP2003530432A publication Critical patent/JP2003530432A/ja
Publication of JP2003530432A5 publication Critical patent/JP2003530432A5/ja
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
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    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
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    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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JPWO2013051266A1 (ja) * 2011-10-03 2015-03-30 独立行政法人国立長寿医療研究センター タウ凝集阻害剤
JP2017119722A (ja) * 2011-10-03 2017-07-06 国立研究開発法人国立長寿医療研究センター タウ凝集阻害剤
US9907799B2 (en) 2013-04-02 2018-03-06 The Doshisha Tau aggregation inhibitor
JP2019521964A (ja) * 2016-05-13 2019-08-08 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー アドレナリン受容体調節化合物およびその使用方法

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