CA2386509A1 - Recepteurs couples par des proteines g exprimes dans le cerveau - Google Patents
Recepteurs couples par des proteines g exprimes dans le cerveau Download PDFInfo
- Publication number
- CA2386509A1 CA2386509A1 CA002386509A CA2386509A CA2386509A1 CA 2386509 A1 CA2386509 A1 CA 2386509A1 CA 002386509 A CA002386509 A CA 002386509A CA 2386509 A CA2386509 A CA 2386509A CA 2386509 A1 CA2386509 A1 CA 2386509A1
- Authority
- CA
- Canada
- Prior art keywords
- transmembrane receptor
- polypeptide
- seq
- amino acid
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Abstract
La présente invention concerne des gènes codant des récepteurs couplés par des protéines G jusqu'ici inconnus, des constructions et des cellules hôtes recombinées incorporant les gènes; les polypeptides GPCR codés par les gènes; des anticorps dirigés contre les polypeptides; et des méthodes de production et d'utilisation de tout ce qui est précité.
Applications Claiming Priority (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42785999A | 1999-10-27 | 1999-10-27 | |
US42802099A | 1999-10-27 | 1999-10-27 | |
US42811499A | 1999-10-27 | 1999-10-27 | |
US42765399A | 1999-10-27 | 1999-10-27 | |
US09/427,859 | 1999-10-27 | ||
US09/428,020 | 1999-10-27 | ||
US09/427,653 | 1999-10-27 | ||
US09/428,114 | 1999-10-27 | ||
US42969599A | 1999-10-28 | 1999-10-28 | |
US42967699A | 1999-10-28 | 1999-10-28 | |
US42955599A | 1999-10-28 | 1999-10-28 | |
US42951799A | 1999-10-28 | 1999-10-28 | |
US09/429,517 | 1999-10-28 | ||
US09/429,676 | 1999-10-28 | ||
US09/429,695 | 1999-10-28 | ||
US09/429,555 | 1999-10-28 | ||
US45439999A | 1999-12-03 | 1999-12-03 | |
US09/454,399 | 1999-12-03 | ||
US48179400A | 2000-01-12 | 2000-01-12 | |
US09/481,794 | 2000-01-12 | ||
PCT/US2000/029601 WO2001031014A2 (fr) | 1999-10-27 | 2000-10-27 | Recepteurs couples par des proteines g exprimes dans le cerveau |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2386509A1 true CA2386509A1 (fr) | 2001-05-03 |
Family
ID=27581260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002386509A Abandoned CA2386509A1 (fr) | 1999-10-27 | 2000-10-27 | Recepteurs couples par des proteines g exprimes dans le cerveau |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1230361A2 (fr) |
AU (1) | AU1575601A (fr) |
CA (1) | CA2386509A1 (fr) |
WO (1) | WO2001031014A2 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7119190B2 (en) | 1997-04-14 | 2006-10-10 | Arena Pharmaceuticals, Inc. | Endogenous and non-endogenous versions of human G protein-coupled receptors |
US6555339B1 (en) | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
WO2000050458A1 (fr) * | 1999-02-26 | 2000-08-31 | Smithkline Beecham Corporation | Clonage du recepteur 7tm (axor 17) du type p2y |
US6790631B1 (en) | 1999-10-05 | 2004-09-14 | Agensys, Inc. | G protein-coupled receptor up-regulated in prostate cancer and uses thereof |
US7361338B2 (en) | 1999-10-05 | 2008-04-22 | Agensys, Inc. | Methods to inhibit growth of prostate cancer cells |
WO2001036471A2 (fr) * | 1999-11-17 | 2001-05-25 | Arena Pharmaceuticals, Inc. | Versions endogenes et non-endogenes de recepteurs couples a la proteine g humaine |
GB0001700D0 (en) * | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Novel protein |
CA2408134A1 (fr) * | 2000-05-18 | 2001-11-22 | Incyte Genomics, Inc. | Recepteurs couples aux proteines g |
AU2001269014A1 (en) * | 2000-05-18 | 2001-11-26 | Bayer Aktiengesellschaft | Regulation of human follicle stimulating hormone-like g protein-coupled receptor |
WO2001094385A2 (fr) * | 2000-06-05 | 2001-12-13 | Bayer Aktiengesellschaft | Regulation du recepteur couple a la proteine humaine g de type hm74 |
US20030212255A1 (en) * | 2000-07-26 | 2003-11-13 | Muralidhara Padigaru | Novel proteins and nucleic acids encoding same |
AU2002352554A1 (en) * | 2001-06-26 | 2003-03-03 | Novartis Ag | G protein coupled receptors and dna sequences thereof |
US6902902B2 (en) | 2001-11-27 | 2005-06-07 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders |
JP2005512562A (ja) * | 2001-12-20 | 2005-05-12 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | 新規なg蛋白質結合受容体、gave7 |
RU2004125608A (ru) * | 2002-01-23 | 2005-04-20 | Авентис Фармасьютикалз Инк. (Us) | Нуклеиновая кислота, кодирующая рецептор, связанный с g-белком, и ее применение |
AU2003220913A1 (en) * | 2002-03-19 | 2003-09-29 | Tanabe Seiyaku Co., Ltd. | Novel g protein-coupled recepotrs and genes thereof |
US7527935B2 (en) | 2002-03-19 | 2009-05-05 | Mitsubishi Tanabe Pharma Corporation | G-protein coupled receptor having eicosanoid as ligand and gene thereof |
US20080260744A1 (en) | 2002-09-09 | 2008-10-23 | Omeros Corporation | G protein coupled receptors and uses thereof |
US7524638B1 (en) | 2003-06-27 | 2009-04-28 | Osi Pharmaceuticals, Inc. | Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease |
WO2006024449A2 (fr) * | 2004-09-01 | 2006-03-09 | Bayer Healthcare Ag | Diagnostic et traitement des maladies associees au recepteur 1 de cysteinyl leucotriene (cyslt1) |
WO2006040534A2 (fr) * | 2004-10-11 | 2006-04-20 | Paradigm Therapeutics Limited | Methode |
WO2008061209A2 (fr) * | 2006-11-15 | 2008-05-22 | Omeros Corporation | Récepteurs couplés à la protéine g et leurs utilisations |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5955308A (en) * | 1997-06-18 | 1999-09-21 | Smithkline Beecham Corporation | cDNA clone HEAOD54 that encodes a human 7-transmembrane receptor |
DE69931360T2 (de) * | 1998-03-12 | 2007-02-08 | Astellas Pharma Inc. | Neue, an ein g-protein gekoppelte rezeptorproteine |
US6071722A (en) * | 1998-04-24 | 2000-06-06 | Smithkline Beecham Corporation | Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1) |
AU5801099A (en) * | 1998-09-02 | 2000-03-21 | Millennium Pharmaceuticals, Inc. | 14926 receptor, a novel g-protein coupled receptor |
CA2348688A1 (fr) * | 1998-10-13 | 2000-04-20 | Arena Pharmaceuticals, Inc. | Recepteurs non-endogenes de la proteine g humaine ayant une activite constitutive |
ES2289610T3 (es) * | 1998-11-20 | 2008-02-01 | Arena Pharmaceuticals, Inc. | Receptor acoplado a proteina g humano huerfano rup3. |
EP1200587A2 (fr) * | 1999-07-21 | 2002-05-02 | Incyte Genomics, Inc. | Recepteurs et proteines associees |
-
2000
- 2000-10-27 AU AU15756/01A patent/AU1575601A/en not_active Abandoned
- 2000-10-27 EP EP00978278A patent/EP1230361A2/fr not_active Withdrawn
- 2000-10-27 CA CA002386509A patent/CA2386509A1/fr not_active Abandoned
- 2000-10-27 WO PCT/US2000/029601 patent/WO2001031014A2/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1230361A2 (fr) | 2002-08-14 |
WO2001031014A3 (fr) | 2002-06-06 |
WO2001031014A2 (fr) | 2001-05-03 |
AU1575601A (en) | 2001-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |