CA2385029A1 - Dispositif de traitement rapide d'echantillons d'adn a manipulation des liquides, thermocyclage, et purification integres - Google Patents
Dispositif de traitement rapide d'echantillons d'adn a manipulation des liquides, thermocyclage, et purification integres Download PDFInfo
- Publication number
- CA2385029A1 CA2385029A1 CA002385029A CA2385029A CA2385029A1 CA 2385029 A1 CA2385029 A1 CA 2385029A1 CA 002385029 A CA002385029 A CA 002385029A CA 2385029 A CA2385029 A CA 2385029A CA 2385029 A1 CA2385029 A1 CA 2385029A1
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- Prior art keywords
- capillaries
- capillary
- capillary cassette
- fluid
- cassette
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Water Supply & Treatment (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Genetics & Genomics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Saccharide Compounds (AREA)
Abstract
L'invention porte dans une exécution sur une cassette capilaire facilitant des dialyses rapides ou le thermocyclage, via des liquides ou des gaz d'échantillons inférieurs au microlitre. Dans une autre exécution la cassette est configurée pour être utilisée avec une machine de manipulation des fluides permettant un traitement automatique à fort débit, les dyalises et le thermocyclage s'effectuant lorsque la cassette est montée sur ladite machine. D'autres exécutions permettent des débits plus élevés en recourant à des hôtels effectuant le traitement simultané de plusieurs cassettes. Les capacités de ces hotels permettent la dyalise, le thermocyclage, le nettoyage et la régénération chimique. Citons à titre d'exemple des applications englobant non exclusivement la PCR, le séquencage de l'ADN, la ligation des oligonucléotides, la LCR, l'extension de nucléotides isolés, le traitement par l'exonucléase, et les essais d'hybridation d'oligonucléotides.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15529999P | 1999-09-21 | 1999-09-21 | |
US60/155,299 | 1999-09-21 | ||
PCT/US2000/025851 WO2001021310A2 (fr) | 1999-09-21 | 2000-09-21 | Dispositif de traitement rapide d'echantillons d'adn a manipulation des liquides, thermocyclage, et purification integres |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2385029A1 true CA2385029A1 (fr) | 2001-03-29 |
Family
ID=22554862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002385029A Abandoned CA2385029A1 (fr) | 1999-09-21 | 2000-09-21 | Dispositif de traitement rapide d'echantillons d'adn a manipulation des liquides, thermocyclage, et purification integres |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1214149A2 (fr) |
JP (1) | JP2004500552A (fr) |
AU (1) | AU7597900A (fr) |
CA (1) | CA2385029A1 (fr) |
WO (1) | WO2001021310A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150137015A1 (en) * | 2012-07-12 | 2015-05-21 | Agency For Science, Technology And Research | Connector for microfluidic device, a method for injecting fluid into microfluidic device using the connector and a method of providing and operating a valve |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0202415D0 (sv) * | 2001-12-11 | 2002-08-13 | Thomas Laurell | Dockable processing module |
US6833238B2 (en) | 2002-01-04 | 2004-12-21 | Applera Corporation | Petal-array support for use with microplates |
EP1525052A1 (fr) * | 2002-07-26 | 2005-04-27 | Applera Corporation | Particule d'echange ionique a exclusion de dimension |
DE10307227A1 (de) * | 2003-02-14 | 2004-08-26 | Cytocentrics Ccs Gmbh | Verfahren und Vorrichtung zum Kontaktieren einer Mikrofluidstruktur |
DE10349513B4 (de) * | 2003-10-23 | 2006-08-31 | Eads Space Transportation Gmbh | Experimentiervorrichtung |
EP1715954A1 (fr) * | 2004-02-18 | 2006-11-02 | Applera Corporation | Essais biologiques a etapes multiples sur des plates-formes d'applications micro-fluidiques modulaires |
CN101094722A (zh) * | 2004-08-04 | 2007-12-26 | 斯平克斯公司 | 用于将微流体装置与流体处理装置接口的装置和方法 |
DE102005026585A1 (de) * | 2005-05-03 | 2006-11-09 | Forschungszentrum Jülich GmbH | Verfahren zur Probenaufgabe in Module sowie Adapter |
EP1925364A1 (fr) * | 2006-11-23 | 2008-05-28 | Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO | Connecteur microfluidique multiple |
ES2538691T3 (es) | 2012-02-24 | 2015-06-23 | F. Hoffmann-La Roche Ag | Cierre con tira de septo |
EP2848309B1 (fr) * | 2013-09-13 | 2020-06-10 | NanoTemper Technologies GmbH | Support pour capillaires |
KR20160114494A (ko) * | 2015-03-24 | 2016-10-05 | 삼성전자주식회사 | 미세유동 장치 및 이를 포함하는 시료 분석장치 |
CN108136401B (zh) * | 2015-07-23 | 2021-06-15 | 塞弗德公司 | 热控设备及其使用方法 |
CA3107571A1 (fr) * | 2018-06-27 | 2020-01-02 | Qcdx Llc | Porte-echantillons biologiques et manipulateur |
GB201818936D0 (en) * | 2018-11-21 | 2019-01-02 | Univ Loughborough | Microfluid device |
EP3890887A4 (fr) * | 2018-12-07 | 2022-10-12 | Element Biosciences, Inc. | Dispositif de cellule d'écoulement et son utilisation |
WO2021155221A2 (fr) * | 2020-01-31 | 2021-08-05 | Western Connecticut Health Network, Inc. | Appareil et procédé de collecte d'échantillons liquides |
CN114854570B (zh) * | 2022-07-05 | 2022-09-02 | 鲲鹏基因(北京)科技有限责任公司 | 温控装置、液冷温控系统及pcr仪 |
GB202212732D0 (en) * | 2022-09-01 | 2022-10-19 | Remedy Biologics Ltd | Methods and systems of material recovery |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3915652A (en) * | 1973-08-16 | 1975-10-28 | Samuel Natelson | Means for transferring a liquid in a capillary open at both ends to an analyzing system |
US5840573A (en) * | 1994-02-01 | 1998-11-24 | Fields; Robert E. | Molecular analyzer and method of use |
US5976896A (en) * | 1994-06-06 | 1999-11-02 | Idexx Laboratories, Inc. | Immunoassays in capillary tubes |
US5560811A (en) * | 1995-03-21 | 1996-10-01 | Seurat Analytical Systems Incorporated | Capillary electrophoresis apparatus and method |
US5785926A (en) * | 1995-09-19 | 1998-07-28 | University Of Washington | Precision small volume fluid processing apparatus |
-
2000
- 2000-09-21 JP JP2001524729A patent/JP2004500552A/ja not_active Withdrawn
- 2000-09-21 AU AU75979/00A patent/AU7597900A/en not_active Abandoned
- 2000-09-21 EP EP00965231A patent/EP1214149A2/fr not_active Withdrawn
- 2000-09-21 WO PCT/US2000/025851 patent/WO2001021310A2/fr not_active Application Discontinuation
- 2000-09-21 CA CA002385029A patent/CA2385029A1/fr not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150137015A1 (en) * | 2012-07-12 | 2015-05-21 | Agency For Science, Technology And Research | Connector for microfluidic device, a method for injecting fluid into microfluidic device using the connector and a method of providing and operating a valve |
Also Published As
Publication number | Publication date |
---|---|
EP1214149A2 (fr) | 2002-06-19 |
WO2001021310A3 (fr) | 2002-01-17 |
WO2001021310A9 (fr) | 2002-10-03 |
JP2004500552A (ja) | 2004-01-08 |
WO2001021310A2 (fr) | 2001-03-29 |
AU7597900A (en) | 2001-04-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |